| # | Title | Journal | Year | Citations |
|---|
| 1 | In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers | Nature Medicine | 2012 | 1,299 |
| 2 | Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper | Journal of Extracellular Vesicles | 2015 | 1,020 |
| 3 | Large-scale genotyping identifies 41 new loci associated with breast cancer risk | Nature Genetics | 2013 | 960 |
| 4 | State of the art and future directions of scaffold-based bone engineering from a biomaterials perspective | Journal of Tissue Engineering and Regenerative Medicine | 2007 | 835 |
| 5 | Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 | JAMA Oncology | 2022 | 719 |
| 6 | Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches | Science | 2019 | 676 |
| 7 | Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium | Stem Cell Research | 2008 | 531 |
| 8 | Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer | Nature Genetics | 2015 | 513 |
| 9 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer | Nature Genetics | 2013 | 493 |
| 10 | Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration | Osteoarthritis and Cartilage | 2016 | 480 |
| 11 | Genome-wide association studies identify four ER negative–specific breast cancer risk loci | Nature Genetics | 2013 | 374 |
| 12 | Oncogenic Pathway Combinations Predict Clinical Prognosis in Gastric Cancer | PLoS Genetics | 2009 | 354 |
| 13 | MSC exosome as a cell-free MSC therapy for cartilage regeneration: Implications for osteoarthritis treatment | Seminars in Cell and Developmental Biology | 2017 | 351 |
| 14 | Derivation of Clinically Compliant MSCs from CD105+, CD24− Differentiated Human ESCs | Stem Cells | 2007 | 303 |
| 15 | Titin-truncating variants affect heart function in disease cohorts and the general population | Nature Genetics | 2017 | 255 |
| 16 | MSC exosome works through a protein-based mechanism of action | Biochemical Society Transactions | 2018 | 252 |
| 17 | Tracking transplanted cells in live animal using upconversion fluorescent nanoparticles | Biomaterials | 2009 | 248 |
| 18 | Elucidating the Secretion Proteome of Human Embryonic Stem Cell-derived Mesenchymal Stem Cells | Molecular and Cellular Proteomics | 2007 | 240 |
| 19 | Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease | Immunity | 2021 | 233 |
| 20 | A High-Dimensional Atlas of Human T Cell Diversity Reveals Tissue-Specific Trafficking and Cytokine Signatures | Immunity | 2016 | 232 |
| 21 | Determinants of burnout and other aspects of psychological well-being in healthcare workers during the Covid-19 pandemic: A multinational cross-sectional study | PLoS ONE | 2021 | 215 |
| 22 | Immunogenic Tumor Cell Death Induced by Chemoradiotherapy in Patients with Esophageal Squamous Cell Carcinoma | Cancer Research | 2012 | 209 |
| 23 | Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2 | Nature | 2017 | 199 |
| 24 | Lamin B1 fluctuations have differential effects on cellular proliferation and senescence | Journal of Cell Biology | 2013 | 193 |
| 25 | Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism | Cell Metabolism | 2016 | 186 |
| 26 | Repair of Calvarial Defects with Customised Tissue-Engineered Bone Grafts II. Evaluation of Cellular Efficiency and Efficacyin Vivo | Tissue Engineering | 2003 | 181 |
| 27 | Investigation of hemodynamics in the development of dissecting aneurysm within patient-specific dissecting aneurismal aortas using computational fluid dynamics (CFD) simulations | Journal of Biomechanics | 2011 | 180 |
| 28 | ‘See-saw’ expression of microRNA-198 and FSTL1 from a single transcript in wound healing | Nature | 2013 | 178 |
| 29 | CD44v8-10 Is a Cancer-Specific Marker for Gastric Cancer Stem Cells | Cancer Research | 2014 | 176 |
| 30 | Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer | Cancer Cell | 2018 | 175 |
| 31 | microRNA‐122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma | Molecular Systems Biology | 2010 | 169 |
| 32 | Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia | Nature Medicine | 2016 | 169 |
| 33 | Interleukin 17A Promotes Hepatocellular Carcinoma Metastasis via NF-kB Induced Matrix Metalloproteinases 2 and 9 Expression | PLoS ONE | 2011 | 168 |
| 34 | In vitro characterization of natural and synthetic dermal matrices cultured with human dermal fibroblasts | Biomaterials | 2004 | 162 |
| 35 | Strategies for directing the differentiation of stem cells into the cardiomyogenic lineage in vitro | Cardiovascular Research | 2004 | 159 |
| 36 | Role of Vascular Smooth Muscle Cell Plasticity and Interactions in Vessel Wall Inflammation | Frontiers in Immunology | 2020 | 153 |
| 37 | The Challenge to Measure Cell Proliferation in Two and Three Dimensions | Tissue Engineering | 2005 | 152 |
| 38 | Bioinspired Cell-Derived Nanovesicles versus Exosomes as Drug Delivery Systems: a Cost-Effective Alternative | Scientific Reports | 2017 | 146 |
| 39 | Biocompatibility of electroactive polymers in tissues | Journal of Biomedical Materials Research Part B | 2000 | 143 |
| 40 | Fabrication of monodispersed Taxol-loaded particles using electrohydrodynamic atomization | Journal of Controlled Release | 2005 | 141 |
| 41 | Derivation and characterization of human fetal MSCs: An alternative cell source for large-scale production of cardioprotective microparticles | Journal of Molecular and Cellular Cardiology | 2010 | 137 |
| 42 | Longer Examination Time Improves Detection of Gastric Cancer During Diagnostic Upper Gastrointestinal Endoscopy | Clinical Gastroenterology and Hepatology | 2015 | 136 |
| 43 | Human Skin Keloid Fibroblasts Display Bioenergetics of Cancer Cells | Journal of Investigative Dermatology | 2008 | 132 |
| 44 | Tubular nanofiber scaffolds for tissue engineered small‐diameter vascular grafts | Journal of Biomedical Materials Research - Part A | 2009 | 132 |
| 45 | Inhibition of escherichia coli and proteus mirabilis adhesion and biofilm formation on medical grade silicone surface | Biotechnology and Bioengineering | 2012 | 131 |
| 46 | Female Breast Cancer Incidence Among Asian and Western Populations: More Similar Than Expected | Journal of the National Cancer Institute | 2015 | 127 |
| 47 | ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer | Gastroenterology | 2016 | 127 |
| 48 | Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles | Cytotherapy | 2021 | 125 |
| 49 | Repair of Calvarial Defects with Customized Tissue-Engineered Bone Grafts I. Evaluation of Osteogenesis in a Three-Dimensional Culture System | Tissue Engineering | 2003 | 121 |
| 50 | Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antrum of Mice | Gastroenterology | 2017 | 121 |
