| # | Title | Journal | Year | Citations |
|---|
| 1 | The structure and properties of the sense of coherence scale | Social Science and Medicine | 1993 | 2,563 |
| 2 | Consolidated Health Economic Evaluation Reporting Standards (CHEERS)—Explanation and Elaboration: A Report of the ISPOR Health Economic Evaluation Publication Guidelines Good Reporting Practices Task Force | Value in Health | 2013 | 1,657 |
| 3 | Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking | Nature Genetics | 1996 | 1,451 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 5 | Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement | BMJ, The | 2013 | 1,082 |
| 6 | Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood | Nature Neuroscience | 2006 | 1,072 |
| 7 | Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study | Gastroenterology | 2021 | 913 |
| 8 | Temporal trends in sperm count: a systematic review and meta-regression analysis | Human Reproduction Update | 2017 | 899 |
| 9 | IL-1 is required for tumor invasiveness and angiogenesis | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 890 |
| 10 | Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity | Nature Reviews Endocrinology | 2020 | 790 |
| 11 | A reference map of the human binary protein interactome | Nature | 2020 | 724 |
| 12 | Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement | Lancet Diabetes and Endocrinology,the | 2019 | 687 |
| 13 | Acute generalized exanthematous pustulosis (AGEP) - A clinical reaction pattern | Journal of Cutaneous Pathology | 2001 | 616 |
| 14 | Translation and validation of study instruments for cross-cultural research | Gastroenterology | 2004 | 608 |
| 15 | The fundamental link between pneumococcal carriage and disease | Expert Review of Vaccines | 2012 | 519 |
| 16 | Consolidated Health Economic Evaluation Reporting Standards (CHEERS) Statement | Value in Health | 2013 | 513 |
| 17 | Macrophage Infiltration into OmentalVersusSubcutaneous Fat across Different Populations: Effect of Regional Adiposity and the Comorbidities of Obesity | Journal of Clinical Endocrinology and Metabolism | 2007 | 497 |
| 18 | Lycopene is a more potent inhibitor of human cancer cell proliferation than either α‐carotene or β‐carotene | Nutrition and Cancer | 1995 | 496 |
| 19 | The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions | Cancer and Metastasis Reviews | 2006 | 495 |
| 20 | Gestational diabetes: the need for a common ground | Lancet, The | 2009 | 493 |
| 21 | Effect of a Probiotic Infant Formula on Infections in Child Care Centers: Comparison of Two Probiotic Agents | Pediatrics | 2005 | 492 |
| 22 | Bioengineered Cardiac Grafts : A New Approach to Repair the Infarcted Myocardium? | Circulation | 2000 | 482 |
| 23 | IL-1α and IL-1β Recruit Different Myeloid Cells and Promote Different Stages of Sterile Inflammation | Journal of Immunology | 2011 | 446 |
| 24 | Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes | Diabetes | 1998 | 406 |
| 25 | Classification of current anticancer immunotherapies | Oncotarget | 2014 | 395 |
| 26 | The global prevalence of IBS in adults remains elusive due to the heterogeneity of studies: a Rome Foundation working team literature review | Gut | 2017 | 368 |
| 27 | Prior Statin Therapy Is Associated With a Decreased Rate of Severe Sepsis | Circulation | 2004 | 366 |
| 28 | Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding | Journal of Lipid Research | 2008 | 366 |
| 29 | Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1 | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 362 |
| 30 | Irritable bowel syndrome | Lancet, The | 2020 | 348 |
| 31 | Attributable Mortality Rate for Carbapenem-Resistant Klebsiella pneumoniae Bacteremia | Infection Control and Hospital Epidemiology | 2009 | 345 |
| 32 | Reduction of Nasopharyngeal Carriage ofStreptococcus pneumoniaeafter Administration of a 9‐Valent Pneumococcal Conjugate Vaccine to Toddlers Attending Day Care Centers | Journal of Infectious Diseases | 2002 | 338 |
| 33 | Pseudohypoaldosteronism in a preterm infant: Intrauterine presentation as hydramnios | Journal of Pediatrics | 1992 | 331 |
| 34 | Recurrent Implantation Failure-update overview on etiology, diagnosis, treatment and future directions | Reproductive Biology and Endocrinology | 2018 | 330 |
| 35 | Lycopene Interferes With Cell Cycle Progression and Insulin-Like Growth Factor I Signaling in Mammary Cancer Cells | Nutrition and Cancer | 2000 | 315 |
| 36 | Comprehensive Survival Analysis of a Cohort of Patients with Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis | Journal of Investigative Dermatology | 2013 | 312 |
| 37 | Maternal anemia during pregnancy is an independent risk factor for low birthweight and preterm delivery | European Journal of Obstetrics, Gynecology and Reproductive Biology | 2005 | 311 |
| 38 | Efficacy of Thalamocortical and Intracortical Synaptic Connections | Neuron | 1999 | 310 |
| 39 | Hospital Incidence and Outcomes of the Acute Respiratory Distress Syndrome Using the Kigali Modification of the Berlin Definition | American Journal of Respiratory and Critical Care Medicine | 2016 | 303 |
| 40 | Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti–PD-1 for tumor abrogation | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 302 |
| 41 | Cerebrospinal Cytokine Levels in Patients with Acute Depression | Neuropsychobiology | 1999 | 297 |
| 42 | A CSF and postmortem brain study of d-serine metabolic parameters in schizophrenia | Schizophrenia Research | 2007 | 294 |
| 43 | Vitamin D supplementation to prevent acute respiratory infections: a systematic review and meta-analysis of aggregate data from randomised controlled trials | Lancet Diabetes and Endocrinology,the | 2021 | 292 |
| 44 | Autonomic dysfunction in patients with fibromyalgia: Application of power spectral analysis of heart rate variability | Seminars in Arthritis and Rheumatism | 2000 | 289 |
| 45 | Low Penetrance, Broad Resistance, and Favorable Outcome of Interleukin 12 Receptor β1 Deficiency | Journal of Experimental Medicine | 2003 | 286 |
| 46 | Anatomy and physiology of the blood–brain barrier | Seminars in Cell and Developmental Biology | 2015 | 286 |
| 47 | CONSOLIDATED HEALTH ECONOMIC EVALUATION REPORTING STANDARDS (CHEERS) STATEMENT | International Journal of Technology Assessment in Health Care | 2013 | 281 |
| 48 | Propagating Neuronal Discharges in Neocortical Slices: Computational and Experimental Study | Journal of Neurophysiology | 1997 | 278 |
| 49 | Overview and introduction: The blood–brain barrier in health and disease | Epilepsia | 2012 | 275 |
| 50 | Anti-Inflammatory Activity of Natural Products | Molecules | 2016 | 272 |
