| # | Title | Journal | Year | Citations |
|---|
| 1 | The Human Microbiome Project | Nature | 2007 | 4,750 |
| 2 | PyNAST: a flexible tool for aligning sequences to a template alignment | Bioinformatics | 2010 | 3,400 |
| 3 | The Impact of the Gut Microbiota on Human Health: An Integrative View | Cell | 2012 | 2,920 |
| 4 | Quantitative and Qualitative β Diversity Measures Lead to Different Insights into Factors That Structure Microbial Communities | Applied and Environmental Microbiology | 2007 | 2,418 |
| 5 | Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer | Nature Genetics | 2005 | 1,710 |
| 6 | O/C and OM/OC Ratios of Primary, Secondary, and Ambient Organic Aerosols with High-Resolution Time-of-Flight Aerosol Mass Spectrometry | Environmental Science & Technology | 2008 | 1,524 |
| 7 | Worlds within worlds: evolution of the vertebrate gut microbiota | Nature Reviews Microbiology | 2008 | 1,342 |
| 8 | ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure | Cell | 2016 | 1,213 |
| 9 | Stability of Protein Structure and Hydrophobic Interaction | Advances in Protein Chemistry | 1988 | 1,175 |
| 10 | FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT | Cell | 2006 | 1,019 |
| 11 | A small catalytic oligoribonucleotide | Nature | 1987 | 1,012 |
| 12 | Mechanical memory and dosing influence stem cell fate | Nature Materials | 2014 | 943 |
| 13 | Defining seasonal marine microbial community dynamics | ISME Journal | 2012 | 928 |
| 14 | PySCF: the Python‐based simulations of chemistry framework | Wiley Interdisciplinary Reviews: Computational Molecular Science | 2018 | 894 |
| 15 | Defining the human microbiome | Nutrition Reviews | 2012 | 789 |
| 16 | Understanding atmospheric organic aerosols via factor analysis of aerosol mass spectrometry: a review | Analytical and Bioanalytical Chemistry | 2011 | 764 |
| 17 | Longitudinal analysis of microbial interaction between humans and the indoor environment | Science | 2014 | 751 |
| 18 | Microbiota Regulate Intestinal Absorption and Metabolism of Fatty Acids in the Zebrafish | Cell Host and Microbe | 2012 | 717 |
| 19 | Mapping protein post-translational modifications with mass spectrometry | Nature Methods | 2007 | 694 |
| 20 | Light-driven dinitrogen reduction catalyzed by a CdS:nitrogenase MoFe protein biohybrid | Science | 2016 | 676 |
| 21 | Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions | Nature Structural Biology | 1998 | 657 |
| 22 | Structural features that give rise to the unusual stability of RNA hairpins containing GNRA loops | Science | 1991 | 649 |
| 23 | Organocatalyzed atom transfer radical polymerization driven by visible light | Science | 2016 | 649 |
| 24 | Short pyrosequencing reads suffice for accurate microbial community analysis | Nucleic Acids Research | 2007 | 638 |
| 25 | Heat‐ or Water‐Driven Malleability in a Highly Recyclable Covalent Network Polymer | Advanced Materials | 2014 | 636 |
| 26 | Deconvolution and Quantification of Hydrocarbon-like and Oxygenated Organic Aerosols Based on Aerosol Mass Spectrometry | Environmental Science & Technology | 2005 | 617 |
| 27 | Experimental and analytical tools for studying the human microbiome | Nature Reviews Genetics | 2012 | 601 |
| 28 | Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function | Cell | 2013 | 600 |
| 29 | Distinct stages in stress granule assembly and disassembly | ELife | 2016 | 593 |
| 30 | DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration | Nature | 2011 | 573 |
| 31 | Recent advances in understanding secondary organic aerosol: Implications for global climate forcing | Reviews of Geophysics | 2017 | 548 |
| 32 | Subsampled open-reference clustering creates consistent, comprehensive OTU definitions and scales to billions of sequences | PeerJ | 2014 | 535 |
| 33 | DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88 | Cell | 2012 | 526 |
| 34 | Accurate taxonomy assignments from 16S rRNA sequences produced by highly parallel pyrosequencers | Nucleic Acids Research | 2008 | 508 |
| 35 | Using QIIME to Analyze 16S rRNA Gene Sequences from Microbial Communities | Current Protocols in Bioinformatics | 2011 | 507 |
| 36 | The generality of self-splicing RNA: Relationship to nuclear mRNA splicing | Cell | 1986 | 493 |
| 37 | Structural visualization of key steps in human transcription initiation | Nature | 2013 | 490 |
| 38 | Ultrathin Direct Atomic Layer Deposition on Composite Electrodes for Highly Durable and Safe Li‐Ion Batteries | Advanced Materials | 2010 | 486 |
| 39 | Using QIIME to Analyze 16S rRNA Gene Sequences from Microbial Communities | Current Protocols in Microbiology | 2012 | 486 |
| 40 | Using coherence to enhance function in chemical and biophysical systems | Nature | 2017 | 477 |
| 41 | Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine | Nature | 2004 | 471 |
| 42 | Fast-Find: a novel computational approach to analyzing combinatorial motifs | BMC Bioinformatics | 2006 | 467 |
| 43 | Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice | Cell Metabolism | 2013 | 464 |
| 44 | Microbiota restoration: natural and supplemented recovery of human microbial communities | Nature Reviews Microbiology | 2011 | 461 |
| 45 | Repairable Woven Carbon Fiber Composites with Full Recyclability Enabled by Malleable Polyimine Networks | Advanced Materials | 2016 | 455 |
| 46 | Nucleic Acid Recognition by OB-Fold Proteins | Annual Review of Biophysics and Biomolecular Structure | 2003 | 448 |
| 47 | Evidence that opioids may have toll-like receptor 4 and MD-2 effects | Brain, Behavior, and Immunity | 2010 | 447 |
| 48 | Human Alu RNA Is a Modular Transacting Repressor of mRNA Transcription during Heat Shock | Molecular Cell | 2008 | 423 |
| 49 | Fast airborne aerosol size and chemistry measurements above Mexico City and Central Mexico during the MILAGRO campaign | Atmospheric Chemistry and Physics | 2008 | 411 |
| 50 | Modularity in promoters and enhancers | Cell | 1989 | 408 |
