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Top Articles

#TitleJournalYearCitations
1Use of Pharmacogenetic and Clinical Factors to Predict the Therapeutic Dose of WarfarinClinical Pharmacology and Therapeutics2008743
2Functions of autophagy in normal and diseased liverAutophagy2013384
3Curcumin Protects the Rat Liver from CCl4-Caused Injury and Fibrogenesis by Attenuating Oxidative Stress and Suppressing InflammationMolecular Pharmacology2008356
4Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cellsAutophagy2018296
5RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cellsAutophagy2020243
6Hepatitis C Virus NS5A Physically Associates with p53 and Regulates p21/waf1 Gene Expression in a p53-Dependent MannerJournal of Virology2001237
7Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker NanogProceedings of the National Academy of Sciences of the United States of America2009210
8Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytesHepatology2011179
9miRNA-29b Suppresses Prostate Cancer Metastasis by Regulating Epithelial–Mesenchymal Transition SignalingMolecular Cancer Therapeutics2012173
10Genetic-based dosing in orthopedic patients beginning warfarin therapyBlood2007164
11SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cellsPLoS Pathogens2020157
12Bitter Melon (Momordica charantia) Extract Inhibits Breast Cancer Cell Proliferation by Modulating Cell Cycle Regulatory Genes and Promotes ApoptosisCancer Research2010153
13Hepatitis C Virus Core Protein Promotes Immortalization of Primary Human HepatocytesVirology2000149
14Hepatitis C Virus Upregulates Beclin1 for Induction of Autophagy and Activates mTOR SignalingJournal of Virology2012145
15Hepatitis C virus core protein: intriguing properties and functional relevanceFEMS Microbiology Letters2001137
16Exosome-Mediated Intercellular Communication between Hepatitis C Virus-Infected Hepatocytes and Hepatic Stellate CellsJournal of Virology2017133
17Anti-miR-203 suppresses ER-positive breast cancer growth and stemness by targeting SOCS3Oncotarget2016132
18Efficacy of SERD/SERM Hybrid-CDK4/6 Inhibitor Combinations in Models of Endocrine Therapy–Resistant Breast CancerClinical Cancer Research2015126
19Knockdown of Autophagy Inhibits Infectious Hepatitis C Virus Release by the Exosomal PathwayJournal of Virology2016124
20N6-methyladenosine modification regulates ferroptosis through autophagy signaling pathway in hepatic stellate cellsRedox Biology2021117
21P53‐dependent induction of ferroptosis is required for artemether to alleviate carbon tetrachloride‐induced liver fibrosis and hepatic stellate cell activationIUBMB Life2019115
22Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cellsRedox Biology2018114
23MBP-1 Upregulates miR-29b, Which Represses Mcl-1, Collagens, and Matrix Metalloproteinase-2 in Prostate Cancer CellsGenes and Cancer2010113
24Mechanisms Underlying Hepatitis C Virus-Associated Hepatic FibrosisCells2019113
25Anti-miR-203 Upregulates SOCS3 Expression in Breast Cancer Cells and Enhances Cisplatin ChemosensitivityGenes and Cancer2011111
26Bitter melon extract inhibits breast cancer growth in preclinical model by inducing autophagic cell deathOncotarget2017107
27Idiopathic Inflammatory Myopathies: Clinical Approach and ManagementFrontiers in Neurology2016106
28Hepatitis C Virus NS5A Protein Impairs TNF-Mediated Hepatic Apoptosis, but Not by an Anti-FAS Antibody, in Transgenic MiceVirology2002105
29Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injuryAmerican Journal of Physiology - Renal Physiology2013105
30Curcumin inhibits gene expression of receptor for advanced glycation end‐products (RAGE) in hepatic stellate cells in vitro by elevating PPARγ activity and attenuating oxidative stressBritish Journal of Pharmacology2012100
31Telbivudine Improves Renal Function in Patients With Chronic Hepatitis BGastroenterology201499
32Curcumin inhibits connective tissue growth factor gene expression in activated hepatic stellate cells in vitro by blocking NF‐κB and ERK signallingBritish Journal of Pharmacology200898
33The BRD7-P53-SLC25A28 axis regulates ferroptosis in hepatic stellate cellsRedox Biology202098
34Interaction between autophagy and senescence is required for dihydroartemisinin to alleviate liver fibrosisCell Death and Disease201797
35Hepatitis C Virus Infection Modulates Expression of Interferon Stimulatory Gene IFITM1 by Upregulating miR-130AJournal of Virology201295
36Up-regulation of circulating miR-20a is correlated with hepatitis C virus-mediated liver disease progressionHepatology201395
37Attitudes Toward Victims of RapeJournal of Interpersonal Violence200593
38Extracellular vesicles: Novel mediator for cell to cell communications in liver pathogenesisMolecular Aspects of Medicine201893
39The interruption of the PDGF and EGF signaling pathways by curcumin stimulates gene expression of PPARγ in rat activated hepatic stellate cell in vitroLaboratory Investigation200792
40Involvement of c-Fos in the Promotion of Cancer Stem-like Cell Properties in Head and Neck Squamous Cell CarcinomaClinical Cancer Research201789
41Activation of peroxisome proliferator-activated receptor-γ by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cellsLaboratory Investigation200886
42NAFLD: Reporting Histologic Findings in Clinical PracticeHepatology202186
43Hepatitis C virus NS5A protein protects against TNF-α mediated apoptotic cell deathVirus Research200085
44Generation of Infectious Hepatitis C Virus in Immortalized Human HepatocytesJournal of Virology200684
45Curcumin suppresses expression of low‐density lipoprotein (LDL) receptor, leading to the inhibition of LDL‐induced activation of hepatic stellate cellsBritish Journal of Pharmacology200984
46Curcumin Eliminates Leptin’s Effects on Hepatic Stellate Cell Activation via Interrupting Leptin SignalingEndocrinology200983
47Autophagy regulates turnover of lipid droplets via ROS-dependent Rab25 activation in hepatic stellate cellRedox Biology201781
48Bitter Melon: Antagonist to CancerPharmaceutical Research201080
49Serum miR-30e and miR-223 as Novel Noninvasive Biomarkers for Hepatocellular CarcinomaAmerican Journal of Pathology201680
50Development and Testing of New Screening Method for Keratan Sulfate in Mucopolysaccharidosis IVAPediatric Research200479