| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor | Nature | 2011 | 1,514 |
| 3 | Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring | Nature | 2010 | 1,214 |
| 4 | Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging | Cell | 2013 | 1,134 |
| 5 | Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial | Lancet, The | 2017 | 908 |
| 6 | The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice | Cell Metabolism | 2014 | 768 |
| 7 | Early human use of marine resources and pigment in South Africa during the Middle Pleistocene | Nature | 2007 | 725 |
| 8 | Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement | Lancet Diabetes and Endocrinology,the | 2019 | 687 |
| 9 | Immune and inflammatory mechanisms in neuropathic pain | Brain Research Reviews | 2006 | 670 |
| 10 | Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication | PLoS Biology | 2013 | 663 |
| 11 | Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study | BMJ: British Medical Journal | 2006 | 634 |
| 12 | Chemotherapy‐induced peripheral neurotoxicity: A critical analysis | Ca-A Cancer Journal for Clinicians | 2013 | 547 |
| 13 | The neuro-immune balance in neuropathic pain: Involvement of inflammatory immune cells, immune-like glial cells and cytokines | Journal of Neuroimmunology | 2010 | 513 |
| 14 | Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats | PLoS ONE | 2011 | 508 |
| 15 | Kynurenine Pathway Metabolites in Humans: Disease and Healthy States | International Journal of Tryptophan Research | 2009 | 501 |
| 16 | Microglia contact induces synapse formation in developing somatosensory cortex | Nature Communications | 2016 | 495 |
| 17 | Dual microglia effects on blood brain barrier permeability induced by systemic inflammation | Nature Communications | 2019 | 492 |
| 18 | Interventions to Slow Aging in Humans: Are We Ready? | Aging Cell | 2015 | 481 |
| 19 | Controversies and priorities in amyotrophic lateral sclerosis | Lancet Neurology, The | 2013 | 454 |
| 20 | Kynurenine is an endothelium-derived relaxing factor produced during inflammation | Nature Medicine | 2010 | 418 |
| 21 | Quinolinic acid, the inescapable neurotoxin | FEBS Journal | 2012 | 418 |
| 22 | Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials | BMJ, The | 2015 | 416 |
| 23 | Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue | PLoS ONE | 2012 | 414 |
| 24 | Microglia: actively surveying and shaping neuronal circuit structure and function | Trends in Neurosciences | 2013 | 403 |
| 25 | An examination of the anxiolytic effects of exercise for people with anxiety and stress-related disorders: A meta-analysis | Psychiatry Research | 2017 | 402 |
| 26 | Defining analytical performance specifications: Consensus Statement from the 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine | Clinical Chemistry and Laboratory Medicine | 2015 | 398 |
| 27 | Mitochondrial dysfunction and insulin resistance: an update | Endocrine Connections | 2015 | 393 |
| 28 | VDJdb: a curated database of T-cell receptor sequences with known antigen specificity | Nucleic Acids Research | 2018 | 391 |
| 29 | High-Intensity Intermittent Exercise and Fat Loss | Journal of Obesity | 2011 | 382 |
| 30 | Contralateral effects of unilateral strength training: evidence and possible mechanisms | Journal of Applied Physiology | 2006 | 375 |
| 31 | ABCA1 and ABCG1 Synergize to Mediate Cholesterol Export to ApoA-I | Arteriosclerosis, Thrombosis, and Vascular Biology | 2006 | 375 |
| 32 | Cytokine aberrations in autism spectrum disorder: a systematic review and meta-analysis | Molecular Psychiatry | 2015 | 371 |
| 33 | The effects of high‐intensity interval training vs. moderate‐intensity continuous training on body composition in overweight and obese adults: a systematic review and meta‐analysis | Obesity Reviews | 2017 | 365 |
| 34 | Tolerance of Whole-Genome Doubling Propagates Chromosomal Instability and Accelerates Cancer Genome Evolution | Cancer Discovery | 2014 | 359 |
| 35 | Changes in Gut Microbiota in Rats Fed a High Fat Diet Correlate with Obesity-Associated Metabolic Parameters | PLoS ONE | 2015 | 353 |
| 36 | Motivating factors and barriers towards exercise in severe mental illness: a systematic review and meta-analysis | Psychological Medicine | 2016 | 345 |
| 37 | Redox Control of Endothelial Function and Dysfunction: Molecular Mechanisms and Therapeutic Opportunities | Antioxidants and Redox Signaling | 2008 | 339 |
| 38 | Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging | Cell | 2018 | 333 |
| 39 | Defining severe familial hypercholesterolaemia and the implications for clinical management: a consensus statement from the International Atherosclerosis Society Severe Familial Hypercholesterolemia Panel | Lancet Diabetes and Endocrinology,the | 2016 | 329 |
| 40 | Phenotypic approaches to obstructive sleep apnoea – New pathways for targeted therapy | Sleep Medicine Reviews | 2018 | 325 |
| 41 | Faecal Microbiota Transplantation for Inflammatory Bowel Disease: A Systematic Review and Meta-analysis | Journal of Crohn's and Colitis | 2017 | 323 |
| 42 | The effects of female sex, viral genotype, andIL28Bgenotype on spontaneous clearance of acute hepatitis C virus infection | Hepatology | 2014 | 320 |
| 43 | Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype | Journal of Neurology, Neurosurgery and Psychiatry | 2015 | 320 |
| 44 | Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis | American Journal of Pathology | 2010 | 304 |
| 45 | Forced Disruption of Anatomy Education in Australia and New Zealand: An Acute Response to the Covid‐19 Pandemic | Anatomical Sciences Education | 2020 | 300 |
| 46 | Uveitis: a global perspective | Ocular Immunology and Inflammation | 2002 | 293 |
| 47 | Inflammation-associated S100 proteins: new mechanisms that regulate function | Amino Acids | 2011 | 290 |
| 48 | Pathogenesis of pterygia: role of cytokines, growth factors, and matrix metalloproteinases | Progress in Retinal and Eye Research | 2004 | 287 |
| 49 | Connecting inflammation with glutamate agonism in suicidality | Neuropsychopharmacology | 2013 | 287 |
| 50 | How much physical activity do people with schizophrenia engage in? A systematic review, comparative meta-analysis and meta-regression | Schizophrenia Research | 2016 | 284 |
