| # | Title | Journal | Year | Citations |
|---|
| 1 | Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes | New England Journal of Medicine | 2017 | 5,629 |
| 2 | Parkinson disease | Nature Reviews Disease Primers | 2017 | 3,048 |
| 3 | Genomic analyses identify molecular subtypes of pancreatic cancer | Nature | 2016 | 2,700 |
| 4 | 2020 International Society of Hypertension Global Hypertension Practice Guidelines | Hypertension | 2020 | 1,895 |
| 5 | Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study | Lancet, The | 2017 | 1,634 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 7 | Extent of illicit drug use and dependence, and their contribution to the global burden of disease | Lancet, The | 2012 | 1,074 |
| 8 | Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy | Cell | 2014 | 871 |
| 9 | Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk | JAMA - Journal of the American Medical Association | 2019 | 830 |
| 10 | The global burden of rheumatoid arthritis: estimates from the Global Burden of Disease 2010 study | Annals of the Rheumatic Diseases | 2014 | 820 |
| 11 | The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness | Lancet Psychiatry,the | 2019 | 815 |
| 12 | The efficacy of smartphone‐based mental health interventions for depressive symptoms: a meta‐analysis of randomized controlled trials | World Psychiatry | 2017 | 755 |
| 13 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
| 14 | Instruction manual for the ILAE 2017 operational classification of seizure types | Epilepsia | 2017 | 699 |
| 15 | Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 578 |
| 16 | A single-cell and spatially resolved atlas of human breast cancers | Nature Genetics | 2021 | 535 |
| 17 | Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats | PLoS ONE | 2011 | 508 |
| 18 | Chronic kidney disease | Lancet, The | 2021 | 478 |
| 19 | Road to resilience: a systematic review and meta-analysis of resilience training programmes and interventions | BMJ Open | 2018 | 460 |
| 20 | Inflammation, Coagulation and Cardiovascular Disease in HIV-Infected Individuals | PLoS ONE | 2012 | 456 |
| 21 | Controversies and priorities in amyotrophic lateral sclerosis | Lancet Neurology, The | 2013 | 454 |
| 22 | 2020 International Society of Hypertension global hypertension practice guidelines | Journal of Hypertension | 2020 | 452 |
| 23 | CD68/macrosialin: not just a histochemical marker | Laboratory Investigation | 2017 | 447 |
| 24 | Aerosol transmission of SARS-CoV-2? Evidence, prevention and control | Environment International | 2020 | 439 |
| 25 | Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection | Journal of Neurochemistry | 2001 | 438 |
| 26 | Mathematical assessment of the impact of non-pharmaceutical interventions on curtailing the 2019 novel Coronavirus | Mathematical Biosciences | 2020 | 438 |
| 27 | Use of and barriers to access to opioid analgesics: a worldwide, regional, and national study | Lancet, The | 2016 | 424 |
| 28 | A meta‐review of “lifestyle psychiatry”: the role of exercise, smoking, diet and sleep in the prevention and treatment of mental disorders | World Psychiatry | 2020 | 424 |
| 29 | Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis | Environmental Health Perspectives | 2016 | 415 |
| 30 | Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue | PLoS ONE | 2012 | 414 |
| 31 | Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies | BMJ: British Medical Journal | 2011 | 411 |
| 32 | Suicide Rates After Discharge From Psychiatric Facilities | JAMA Psychiatry | 2017 | 409 |
| 33 | Canagliflozin for Primary and Secondary Prevention of Cardiovascular Events | Circulation | 2018 | 393 |
| 34 | Estimating the demand for radiotherapy from the evidence: A review of changes from 2003 to 2012 | Radiotherapy and Oncology | 2014 | 387 |
| 35 | High-Intensity Intermittent Exercise and Fat Loss | Journal of Obesity | 2011 | 382 |
| 36 | Reduction of secondary transmission of SARS-CoV-2 in households by face mask use, disinfection and social distancing: a cohort study in Beijing, China | BMJ Global Health | 2020 | 382 |
| 37 | Childhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life | Lancet Respiratory Medicine,the | 2018 | 381 |
| 38 | Health sector accreditation research: a systematic review | International Journal for Quality in Health Care | 2008 | 378 |
| 39 | When Conversation Is Better Than Computation | Journal of the American Medical Informatics Association: JAMIA | 2000 | 374 |
| 40 | The effects of high-intensity intermittent exercise training on fat loss and fasting insulin levels of young women | International Journal of Obesity | 2008 | 373 |
| 41 | A cluster randomised trial of cloth masks compared with medical masks in healthcare workers | BMJ Open | 2015 | 349 |
| 42 | Relative risk of cardiovascular disease among people living with HIV: a systematic review and meta‐analysis | HIV Medicine | 2012 | 346 |
| 43 | Motivating factors and barriers towards exercise in severe mental illness: a systematic review and meta-analysis | Psychological Medicine | 2016 | 345 |
| 44 | Brain potential evidence for an auditory sensory memory deficit in schizophrenia | American Journal of Psychiatry | 1995 | 335 |
| 45 | Prevalence and pattern of neuropsychological impairment in human immunodeficiency virus–infected/acquired immunodeficiency syndrome (HIV/AIDS) patients across pre- and post-highly active antiretroviral therapy eras: A combined study of two cohorts Clinical Report | Journal of NeuroVirology | 2004 | 330 |
| 46 | Effectiveness of Family Integrated Care in neonatal intensive care units on infant and parent outcomes: a multicentre, multinational, cluster-randomised controlled trial | The Lancet Child and Adolescent Health | 2018 | 322 |
| 47 | Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies | Pain | 2018 | 321 |
| 48 | Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype | Journal of Neurology, Neurosurgery and Psychiatry | 2015 | 320 |
| 49 | Association between prediabetes and risk of all cause mortality and cardiovascular disease: updated meta-analysis | BMJ, The | 2020 | 319 |
| 50 | Sustainability science: an integrated approach for health-programme planning | Lancet, The | 2008 | 316 |
