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Top Articles

#TitleJournalYearCitations
1Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activityNature Communications2014257
2Eukaryotic V-ATPase: Novel structural findings and functional insightsBiochimica Et Biophysica Acta - Bioenergetics2014150
3Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilmsNature Communications2016137
4Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer’s diseaseMolecular Brain2019117
5Novel metal(ii) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agentsChemical Science2013111
6The C-terminal 50 Amino Acid Residues of Dengue NS3 Protein Are Important for NS3-NS5 Interaction and Viral ReplicationJournal of Biological Chemistry2015105
7PtdIns(3)P-bound UVRAG coordinates Golgi–ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complexNature Cell Biology201391
8Design of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt‐resistance, and biocompatibilityBiotechnology and Bioengineering201484
9The polyelectrolyte properties of chromatinSoft Matter201276
10A Crystal Structure of the Dengue Virus Non-structural Protein 5 (NS5) Polymerase Delineates Interdomain Amino Acid Residues That Enhance Its Thermostability and de Novo Initiation ActivitiesJournal of Biological Chemistry201374
11Structural insights into the mechanisms of Mg 2+ uptake, transport, and gating by CorAProceedings of the National Academy of Sciences of the United States of America201266
12Insight of brain degenerative protein modifications in the pathology of neurodegeneration and dementia by proteomic profilingMolecular Brain201653
13An Advanced Coarse-Grained Nucleosome Core Particle Model for Computer Simulations of Nucleosome-Nucleosome Interactions under Varying Ionic ConditionsPLoS ONE201346
14Dual-site Interactions of p53 Protein Transactivation Domain with Anti-apoptotic Bcl-2 Family Proteins Reveal a Highly Convergent Mechanism of Divergent p53 PathwaysJournal of Biological Chemistry201342
15Exploring the structure and function of Thermotoga maritima CorA reveals the mechanism of gating and ion selectivity in Co2+/Mg2+ transportBiochemical Journal201342
16NanoSIMS analysis of an isotopically labelled organometallic ruthenium(ii) drug to probe its distribution and state in vitroChemical Communications201539
17Visualizing the Perturbation of Cellular Cyclic di-GMP Levels in Bacterial CellsJournal of the American Chemical Society201337
18Native chemical ubiquitination using a genetically incorporated azidonorleucineChemical Communications201437
19Modelling chromatin structure and dynamics: status and prospectsCurrent Opinion in Structural Biology201236
20Semisynthetic UbH2A reveals different activities of deubiquitinases and inhibitory effects of H2A K119 ubiquitination on H3K36 methylation in mononucleosomesOrganic and Biomolecular Chemistry201636
21P. falciparumRH5-Basigin interaction induces changes in the cytoskeleton of the host RBCCellular Microbiology201736
22Cryo-electron Microscopic Structure of SecA Protein Bound to the 70S RibosomeJournal of Biological Chemistry201435
23A novel strategy for the discrimination of gelatinous Chinese medicines based on enzymatic digestion followed by nano-flow liquid chromatography in tandem with orbitrap mass spectrum detectionInternational Journal of Nanomedicine201535
24Molecular Basis of Bcl-XL-p53 Interaction: Insights from Molecular Dynamics SimulationsPLoS ONE201130
25Dementia-linked amyloidosis is associated with brain protein deamidation as revealed by proteomic profiling of human brain tissuesMolecular Brain201630
26Facile Synthesis of Peptidyl Salicylaldehyde Esters and Its Use in Cyclic Peptide SynthesisOrganic Letters201329
27Solution Structure of the PAS Domain of a Thermophilic YybT Protein Homolog Reveals a Potential Ligand-binding SiteJournal of Biological Chemistry201327
28VP22 core domain from Herpes simplex virus 1 reveals a surprising structural conservation in both the Alpha- and Gammaherpesvirinae subfamiliesJournal of General Virology201526
29Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthaseJournal of Lipid Research201324
30Structural insights into the dual-targeting mechanism of Nutlin-3Biochemical and Biophysical Research Communications201222
31Molecular dynamics simulations demonstrate the regulation of DNA‐DNA attraction by H4 histone tail acetylations and mutationsBiopolymers201422
32The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factorNucleic Acids Research201319
33Principles of electrostatic interactions and self-assembly in lipid/peptide/DNA systems: Applications to gene deliveryAdvances in Colloid and Interface Science201418
34Genetic incorporation of 1,2-aminothiol functionality for site-specific protein modification via thiazolidine formationOrganic and Biomolecular Chemistry201618
35NMR Structure, Localization, and Vesicle Fusion of Chikungunya Virus Fusion PeptideBiochemistry201216
36Structure of the Varicella Zoster Virus Thymidylate Synthase Establishes Functional and Structural Similarities as the Human Enzyme and Potentiates Itself as a Target of BrivudinePLoS ONE201516
37Kefir peptides exhibit antidepressant-like activity in mice through the BDNF/TrkB pathwayJournal of Dairy Science202116
38Functional Evolution in Orthologous Cell-encoded RNA-dependent RNA PolymerasesJournal of Biological Chemistry201613
39Quantitative analysis and comparison of four major flavonol glycosides in the leaves of Toona sinensis (A. Juss.) roemer (chinese toon) from various origins by high-performance liquid chromatography-diode array detector and hierarchical clustering analysisPharmacognosy Magazine201611
40Study of nickel and copper biosorption on brown algaeSargassum angustifolium: application of response surface methodology (RSM)Environmental Technology (United Kingdom)201310
41Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channelJournal of Structural Biology201410
42Suprafenacine, an Indazole-Hydrazide Agent, Targets Cancer Cells Through Microtubule DestabilizationPLoS ONE201410
43Insight into the molecular interaction between the cyclic nucleotide‐binding homology domain and the eag domain of the hERG channelFEBS Letters20149
44Identification of Cellular Targets of MicroRNA-181a in HepG2 Cells: A New Approach for Functional Analysis of MicroRNAsPLoS ONE20159
45Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro StudiesACS Omega20179
46Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteinsBiochemical and Biophysical Research Communications20148
47Computational Study of Uracil Tautomeric Forms in the Ribosome: The Case of Uracil and 5-Oxyacetic Acid Uracil in the First Anticodon Position of tRNAJournal of Physical Chemistry B20188
48Metal-mediated crystallization of the xylose transporter XylE from Escherichia coli in three different crystal formsJournal of Structural Biology20137
49Crystal structure of Plasmodium vivax FK506‐binding protein 25 reveals conformational changes responsible for its noncanonical activityProteins: Structure, Function and Bioinformatics20146
50Rational Design of Fluorescent Biosensor for Cyclic di‐GMPChemBioChem20115