# | Title | Journal | Year | Citations |
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1 | Lipopolysaccharide-mediated Reactive Oxygen Species and Signal Transduction in the Regulation of Interleukin-1 Gene Expression | Journal of Biological Chemistry | 2002 | 450 |
2 | Seselin from Plumbago zeylanica inhibits phytohemagglutinin (PHA)-stimulated cell proliferation in human peripheral blood mononuclear cells | Journal of Ethnopharmacology | 2008 | 263 |
3 | Overexpression of osteopontin is associated with intrahepatic metastasis, early recurrence, and poorer prognosis of surgically resected hepatocellular carcinoma | Cancer | 2003 | 243 |
4 | Acetylation of Snail Modulates the Cytokinome of Cancer Cells to Enhance the Recruitment of Macrophages | Cancer Cell | 2014 | 158 |
5 | Ligands of Macrophage Scavenger Receptor Induce Cytokine Expression via Differential Modulation of Protein Kinase Signaling Pathways | Journal of Biological Chemistry | 2001 | 148 |
6 | Extract of Reishi Polysaccharides Induces Cytokine Expression via TLR4-Modulated Protein Kinase Signaling Pathways | Journal of Immunology | 2004 | 143 |
7 | Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinoma | Oncogene | 2003 | 134 |
8 | Phosphorylation and Stabilization of HURP by Aurora-A: Implication of HURP as a Transforming Target of Aurora-A | Molecular and Cellular Biology | 2005 | 109 |
9 | Regulation of glucose/lipid metabolism and insulin sensitivity by interleukin-4 | International Journal of Obesity | 2012 | 88 |
10 | Clinical applications of fucoidan in translational medicine for adjuvant cancer therapy | Clinical and Translational Medicine | 2019 | 87 |
11 | FLJ10540-elicited cell transformation is through the activation of PI3-kinase/AKT pathway | Oncogene | 2007 | 81 |
12 | Parallel Hybridization Analysis of Multiple Protein Kinase Genes: Identification of Gene Expression Patterns Characteristic of Human Hepatocellular Carcinoma | Genomics | 1998 | 77 |
13 | LTA and LPS mediated activation of protein kinases in the regulation of inflammatory cytokines expression in macrophages | Clinica Chimica Acta | 2006 | 71 |
14 | Immunodetection of pentamer and modified C-reactive protein using surface plasmon resonance biosensing | Biosensors and Bioelectronics | 2006 | 71 |
15 | Fructus Corni suppresses hepatic gluconeogenesis related gene transcription, enhances glucose responsiveness of pancreatic beta-cells, and prevents toxin induced beta-cell death | Journal of Ethnopharmacology | 2008 | 65 |
16 | Overexpression of a Novel Imprinted Gene, PEG10, in Human Hepatocellular Carcinoma and in Regenerating Mouse Livers | Journal of Biomedical Science | 2003 | 63 |
17 | Genetic and antigenic analyses of enterovirus 71 isolates in Taiwan during 1998–2005 | Clinical Microbiology and Infection | 2007 | 63 |
18 | Mutations in PI3K/AKT pathway genes and amplifications of PIK3CA are associated with patterns of recurrence in gastric cancers | Oncotarget | 2016 | 61 |
19 | Tumor Necrosis Factor-α-mediated Protein Kinases in Regulation of Scavenger Receptor and Foam Cell Formation on Macrophage | Journal of Biological Chemistry | 2000 | 54 |
20 | Crystal Structure of Bacillus subtilis Guanine Deaminase | Journal of Biological Chemistry | 2004 | 52 |
21 | A Novel Six-Rhodopsin System in a Single Archaeon | Journal of Bacteriology | 2010 | 49 |
22 | Incorporating hidden Markov models for identifying protein kinase-specific phosphorylation sites | Journal of Computational Chemistry | 2005 | 47 |
23 | Correlation between Ceftriaxone Resistance of Salmonella enterica Serovar Typhimurium and Expression of Outer Membrane Proteins OmpW and Ail/OmpX-Like Protein, Which Are Regulated by BaeR of a Two-Component System | Antimicrobial Agents and Chemotherapy | 2005 | 47 |
24 | POINeT: protein interactome with sub-network analysis and hub prioritization | BMC Bioinformatics | 2009 | 47 |
25 | Translesion-synthesis DNA polymerases participate in replication of the telomeres in Streptomyces | Nucleic Acids Research | 2012 | 43 |
26 | Selective inhibition of enterovirus 71 replication by short hairpin RNAs | Biochemical and Biophysical Research Communications | 2004 | 42 |
27 | Study on the Antiinflammatory Activity of Methanol Extract from SeagrassZostera japonica | Journal of Agricultural and Food Chemistry | 2006 | 42 |
28 | Sensitization of a Tumor, but not Normal Tissue, to the Cytotoxic Effect of Ionizing Radiation using Panax Notoginseng Extract | The American Journal of Chinese Medicine | 2001 | 36 |
29 | Selenite-induced Survival of HuH7 Hepatoma Cells Involves Activation of Focal Adhesion Kinase-Phosphatidylinositol 3-Kinase-Akt Pathway and Rac1 | Journal of Biological Chemistry | 2003 | 33 |
30 | Lysophosphatidic acid-induced oxidized low-density lipoprotein uptake is class A scavenger receptor-dependent in macrophages | Prostaglandins and Other Lipid Mediators | 2008 | 33 |
31 | Identification of mutations in the arginine vasopressin receptor 2 gene causing nephrogenic diabetes insipidus in Chinese patients | Journal of Human Genetics | 2002 | 30 |
32 | Helicobacter pylori stool antigen test in patients with bleeding peptic ulcers | Helicobacter | 2004 | 30 |
33 | Integrative genomics based identification of potential human hepatocarcinogenesis-associated cell cycle regulators: RHAMM as an example | Biochemical and Biophysical Research Communications | 2005 | 30 |
34 | Lysophosphatidic acid-induced interleukin-1β expression is mediated through Gi/Rho and the generation of reactive oxygen species in macrophages | Journal of Biomedical Science | 2008 | 29 |
35 | New Structural Proteins of Halobacterium salinarum Gas Vesicle Revealed by Comparative Proteomics Analysis | Journal of Proteome Research | 2011 | 29 |
36 | Monascus purpureus-fermented rice inhibits tumor necrosis factor-α-induced upregulation of matrix metalloproteinase 2 and 9 in human aortic smooth muscle cells | Journal of Pharmacy and Pharmacology | 2011 | 29 |
37 | Automated Lipid A Structure Assignment from Hierarchical Tandem Mass Spectrometry Data | Journal of the American Society for Mass Spectrometry | 2011 | 26 |
38 | From Midbody Protein−Protein Interaction Network Construction to Novel Regulators in Cytokinesis | Journal of Proteome Research | 2009 | 24 |
39 | Specific repression of mutant K-RAS by 10–23 DNAzyme: Sensitizing cancer cell to anti-cancer therapies | Biochemical and Biophysical Research Communications | 2009 | 22 |
40 | Single point mutation of microRNA may cause butterfly effect on alteration of global gene expression | Biochemical and Biophysical Research Communications | 2011 | 22 |
41 | Ganoderma lucidum polysaccharides prevent platelet‐derived growth factor‐stimulated smooth muscle cell proliferation in vitro and neointimal hyperplasia in the endothelial‐denuded artery in vivo | Journal of Cellular Physiology | 2012 | 21 |
42 | Bioengineering radioresistance by overproduction of RPA, a mammalian-type single-stranded DNA-binding protein, in a halophilic archaeon | Applied Microbiology and Biotechnology | 2014 | 21 |
43 | miR-122-mediated translational repression of PEG10 and its suppression in human hepatocellular carcinoma | Journal of Translational Medicine | 2016 | 21 |
44 | Sequence polymorphism of the group 1 allergen of Bermuda grass pollen | Clinical and Experimental Allergy | 1999 | 20 |
45 | dsAAV type 2-mediated gene transfer of MORS196A-EGFP into spinal cord as a pain management paradigm | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 20 |
46 | Using mass spectrometry to detect buffalo salivary odorant‐binding protein and its post‐translational modifications | Rapid Communications in Mass Spectrometry | 2010 | 20 |
47 | Anti-inflammatory strategies for homocysteine-related cardiovascular disease | Frontiers in Bioscience - Landmark | 2009 | 20 |
48 | Norcantharidin reduced cyclins and cytokines production in human peripheral blood mononuclear cells | Life Sciences | 2009 | 19 |
49 | Identification of lncRNA functions in lung cancer based on associated protein-protein interaction modules | Scientific Reports | 2016 | 18 |
50 | Prevalence of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Taiwanese patients with Type 2 diabetic mellitus | Clinical Biochemistry | 2011 | 17 |