| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies: 2015 update | Annals of the Rheumatic Diseases | 2016 | 743 |
| 3 | Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines | Nature Medicine | 2014 | 734 |
| 4 | Consensus guidelines for the detection of immunogenic cell death | OncoImmunology | 2014 | 686 |
| 5 | Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment | Nature Reviews Rheumatology | 2012 | 675 |
| 6 | Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin | Journal of Clinical Investigation | 2012 | 606 |
| 7 | Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer | Nature | 2010 | 507 |
| 8 | Treatment of psoriatic arthritis in a phase 3 randomised, placebo-controlled trial with apremilast, an oral phosphodiesterase 4 inhibitor | Annals of the Rheumatic Diseases | 2014 | 372 |
| 9 | Vascular occlusion by neutrophil extracellular traps in COVID-19 | EBioMedicine | 2020 | 369 |
| 10 | EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis | Annals of the Rheumatic Diseases | 2012 | 354 |
| 11 | How Cytokine Networks Fuel Inflammation: Toward a cytokine-based disease taxonomy | Nature Medicine | 2013 | 341 |
| 12 | Blockade of TNF-α rapidly inhibits pain responses in the central nervous system | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 308 |
| 13 | Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus | Nature Genetics | 2016 | 283 |
| 14 | TNF-induced structural joint damage is mediated by IL-1 | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 273 |
| 15 | Diabetes Is an Independent Predictor for Severe Osteoarthritis | Diabetes Care | 2013 | 270 |
| 16 | Finalisation and validation of the rheumatoid arthritis impact of disease score, a patient-derived composite measure of impact of rheumatoid arthritis: a EULAR initiative | Annals of the Rheumatic Diseases | 2011 | 238 |
| 17 | Tapering biologic and conventional DMARD therapy in rheumatoid arthritis: current evidence and future directions | Annals of the Rheumatic Diseases | 2016 | 232 |
| 18 | Platelet-derived serotonin links vascular disease and tissue fibrosis | Journal of Experimental Medicine | 2011 | 222 |
| 19 | Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss | Nature Communications | 2015 | 212 |
| 20 | Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus | Nature Medicine | 2013 | 211 |
| 21 | Effects of inflammatory and anti‐inflammatory cytokines on the bone | European Journal of Clinical Investigation | 2011 | 209 |
| 22 | EULAR definition of arthralgia suspicious for progression to rheumatoid arthritis | Annals of the Rheumatic Diseases | 2017 | 209 |
| 23 | PMA and crystal‐induced neutrophil extracellular trap formation involves RIPK1‐RIPK3‐MLKL signaling | European Journal of Immunology | 2016 | 200 |
| 24 | Elaboration of the preliminary Rheumatoid Arthritis Impact of Disease (RAID) score: a EULAR initiative | Annals of the Rheumatic Diseases | 2009 | 190 |
| 25 | Regulatory T Cells Protect from Local and Systemic Bone Destruction in Arthritis | Journal of Immunology | 2010 | 184 |
| 26 | Relapse rates in patients with rheumatoid arthritis in stable remission tapering or stopping antirheumatic therapy: interim results from the prospective randomised controlled RETRO study | Annals of the Rheumatic Diseases | 2016 | 165 |
| 27 | Sodium Overload and Water Influx Activate the NALP3 Inflammasome | Journal of Biological Chemistry | 2011 | 162 |
| 28 | Incidences and Risk Factors of Organ Manifestations in the Early Course of Systemic Sclerosis: A Longitudinal EUSTAR Study | PLoS ONE | 2016 | 158 |
| 29 | Microbiota from Obese Mice Regulate Hematopoietic Stem Cell Differentiation by Altering the Bone Niche | Cell Metabolism | 2015 | 148 |
| 30 | Additive effect of anti-citrullinated protein antibodies and rheumatoid factor on bone erosions in patients with RA | Annals of the Rheumatic Diseases | 2015 | 143 |
| 31 | 12/15-Lipoxygenase Counteracts Inflammation and Tissue Damage in Arthritis | Journal of Immunology | 2009 | 138 |
| 32 | Predictors of progression in systemic sclerosis patients with interstitial lung disease | European Respiratory Journal | 2020 | 134 |
| 33 | Chronic skin inflammation leads to bone loss by IL-17–mediated inhibition of Wnt signaling in osteoblasts | Science Translational Medicine | 2016 | 133 |
| 34 | Nanoparticles size-dependently initiate self-limiting NETosis-driven inflammation | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 128 |
| 35 | Physical phenotype of blood cells is altered in COVID-19 | Biophysical Journal | 2021 | 118 |
| 36 | Src kinases in systemic sclerosis: Central roles in fibroblast activation and in skin fibrosis | Arthritis and Rheumatism | 2008 | 111 |
| 37 | Paraneoplastic syndromes in rheumatology | Nature Reviews Rheumatology | 2014 | 109 |
| 38 | Reactive Oxygen Species Deficiency Induces Autoimmunity with Type 1 Interferon Signature | Antioxidants and Redox Signaling | 2014 | 107 |
| 39 | Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS) | Annals of the Rheumatic Diseases | 2017 | 107 |
| 40 | Repair of bone erosions in rheumatoid arthritis treated with tumour necrosis factor inhibitors is based on bone apposition at the base of the erosion | Annals of the Rheumatic Diseases | 2011 | 102 |
| 41 | GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways | Nature Communications | 2019 | 100 |
| 42 | Risk of infections in rheumatoid arthritis patients treated with tocilizumab | Rheumatology | 2012 | 99 |
| 43 | Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up | Human Molecular Genetics | 2012 | 98 |
| 44 | Interleukin-6 receptor blockade induces limited repair of bone erosions in rheumatoid arthritis: a micro CT study | Annals of the Rheumatic Diseases | 2013 | 98 |
| 45 | Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis | Annals of the Rheumatic Diseases | 2013 | 98 |
| 46 | Successful treatment of inflammatory knee osteoarthritis with tumour necrosis factor blockade | Annals of the Rheumatic Diseases | 2006 | 96 |
| 47 | Animal models for arthritis: innovative tools for prevention and treatment | Annals of the Rheumatic Diseases | 2011 | 92 |
| 48 | Molecular mechanisms of inflammatory bone damage: emerging targets for therapy | Trends in Molecular Medicine | 2008 | 91 |
| 49 | Structural damage in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: traditional views, novel insights gained from TNF blockade, and concepts for the future | Arthritis Research and Therapy | 2011 | 86 |
| 50 | Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis | Annals of the Rheumatic Diseases | 2013 | 81 |
