| # | Title | Journal | Year | Citations |
|---|
| 1 | Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet, The | 2017 | 1,749 |
| 2 | Nivolumab plus chemotherapy versus placebo plus chemotherapy in patients with HER2-negative, untreated, unresectable advanced or recurrent gastric or gastro-oesophageal junction cancer (ATTRACTION-4): a randomised, multicentre, double-blind, placebo-controlled, phase 3 trial | Lancet Oncology, The | 2022 | 268 |
| 3 | Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with biological disease-modifying anti-rheumatic drugs (COAST-V): 16 week results of a phase 3 randomised, double-blind, active-controlled and placebo-controlled trial | Lancet, The | 2018 | 251 |
| 4 | Screening and eradication of Helicobacter pylori for gastric cancer prevention: the Taipei global consensus | Gut | 2020 | 239 |
| 5 | Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IκB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia | European Journal of Pharmacology | 2005 | 228 |
| 6 | Gallic Acid Induces Apoptosis via Caspase-3 and Mitochondrion-Dependent Pathways in Vitro and Suppresses Lung Xenograft Tumor Growth in Vivo | Journal of Agricultural and Food Chemistry | 2009 | 188 |
| 7 | A phase 3 study of nivolumab in previously treated advanced gastric or gastroesophageal junction cancer (ATTRACTION-2): 2-year update data | Gastric Cancer | 2020 | 155 |
| 8 | Complete Induction of Autophagy Is Essential for Cardioprotection in Sepsis | Annals of Surgery | 2011 | 150 |
| 9 | Anti–IFN-γ autoantibodies in adults with disseminated nontuberculous mycobacterial infections are associated with HLA-DRB1*16:02 and HLA-DQB1*05:02 and the reactivation of latent varicella-zoster virus infection | Blood | 2013 | 145 |
| 10 | Identification of α-Enolase as an Autoantigen in Lung Cancer: Its Overexpression Is Associated with Clinical Outcomes | Clinical Cancer Research | 2006 | 138 |
| 11 | NADPH oxidase‐derived superoxide Anion‐induced apoptosis is mediated via the JNK‐dependent activation of NF‐κB in cardiomyocytes exposed to high glucose | Journal of Cellular Physiology | 2012 | 97 |
| 12 | Identification and Characterization of a Novel Integrin-Linked Kinase Inhibitor | Journal of Medicinal Chemistry | 2011 | 83 |
| 13 | Efficacy and safety of ixekizumab through 52 weeks in two phase 3, randomised, controlled clinical trials in patients with active radiographic axial spondyloarthritis (COAST-V and COAST-W) | Annals of the Rheumatic Diseases | 2020 | 76 |
| 14 | Exploring Markers of Exhausted CD8 T Cells to Predict Response to Immune Checkpoint Inhibitor Therapy for Hepatocellular Carcinoma | Liver Cancer | 2021 | 70 |
| 15 | Epidemiology and antifungal susceptibility of candidemia isolates of non- albicans Candida species from cancer patients | Emerging Microbes and Infections | 2017 | 69 |
| 16 | 2020 Taiwan consensus statement on the management of hepatitis C: Part (II) special populations | Journal of the Formosan Medical Association | 2020 | 69 |
| 17 | Menatetrenone, a Vitamin K2 Analogue, Inhibits Hepatocellular Carcinoma Cell Growth by Suppressing Cyclin D1 Expression through Inhibition of Nuclear Factor κB Activation | Clinical Cancer Research | 2007 | 68 |
| 18 | Increased Risk of Dementia in Patients With Chronic Obstructive Pulmonary Disease | Medicine (United States) | 2015 | 61 |
| 19 | Nivolumab in previously treated advanced gastric cancer (ATTRACTION-2): 3-year update and outcome of treatment beyond progression with nivolumab | Gastric Cancer | 2021 | 61 |
| 20 | 2020 Taiwan consensus statement on the management of hepatitis C: part (I) general population | Journal of the Formosan Medical Association | 2020 | 60 |
| 21 | Telbivudine plus pegylated interferon alfa-2a in a randomized study in chronic hepatitis B is associated with an unexpected high rate of peripheral neuropathy | Journal of Hepatology | 2015 | 59 |
| 22 | A targeted next‐generation sequencing in the molecular risk stratification of adult acute myeloid leukemia: implications for clinical practice | Cancer Medicine | 2017 | 48 |
| 23 | Exploratory subgroup analysis of patients with prior trastuzumab use in the ATTRACTION-2 trial: a randomized phase III clinical trial investigating the efficacy and safety of nivolumab in patients with advanced gastric/gastroesophageal junction cancer | Gastric Cancer | 2020 | 45 |
| 24 | Comprehensive review of genetic association studies and meta-analysis on miRNA polymorphisms and rheumatoid arthritis and systemic lupus erythematosus susceptibility | Human Immunology | 2016 | 44 |
| 25 | Taurine prevents free fatty acid-induced hepatic insulin resistance in association with inhibiting JNK1 activation and improving insulin signaling in vivo | Diabetes Research and Clinical Practice | 2010 | 43 |
| 26 | Anti- -enolase Autoantibodies Are Down-regulated in Advanced Cancer Patients | Japanese Journal of Clinical Oncology | 2010 | 42 |
| 27 | Bufalin induces apoptosis in vitro and has Antitumor activity against human lung cancer xenografts in vivo | Environmental Toxicology | 2017 | 40 |
| 28 | The association between chronic obstructive pulmonary disease and Parkinson’s disease: a nationwide population-based retrospective cohort study | QJM - Monthly Journal of the Association of Physicians | 2015 | 39 |
| 29 | Increased Risks of Deep Vein Thrombosis and Pulmonary Embolism in Sjögren Syndrome: A Nationwide Cohort Study | Journal of Rheumatology | 2014 | 35 |
| 30 | Neonatal jaundice and risks of childhood allergic diseases: a population-based cohort study | Pediatric Research | 2015 | 33 |
| 31 | Angiotensin-(1-7) Inhibits Thrombin-Induced Endothelial Phenotypic Changes and Reactive Oxygen Species Production via NADPH Oxidase 5 Downregulation | Frontiers in Physiology | 2017 | 33 |
| 32 | People with tuberculosis are associated with a subsequent risk of depression | European Journal of Internal Medicine | 2014 | 32 |
| 33 | The Incidence of Hepatitis B Surface Antigen Loss Between Hepatitis B E Antigen-Negative Noncirrhotic Patients Who Discontinued or Continued Entecavir Therapy | Journal of Infectious Diseases | 2019 | 32 |
| 34 | Protective effect of Fisetin against angiotensin II-induced apoptosis by activation of IGF-IR-PI3K-Akt signaling in H9c2 cells and spontaneous hypertension rats | Phytomedicine | 2019 | 32 |
| 35 | Icodextrin decreases technique failure and improves patient survival in peritoneal dialysis patients | Nephrology | 2015 | 31 |
| 36 | Fusidic acid resistance among clinical isolates of methicillin-resistant Staphylococcus aureus in a Taiwanese hospital | BMC Microbiology | 2011 | 29 |
| 37 | Factors associated with treatment failure of direct‐acting antivirals for chronic hepatitis C: A real‐world nationwide hepatitis C virus registry programme in Taiwan | Liver International | 2021 | 29 |
| 38 | Hearing Loss is Associated With Risk of Alzheimer’s Disease: A Case-Control Study in Older People | Journal of Epidemiology | 2015 | 28 |
| 39 | A phase 3b study of sofosbuvir plus ribavirin in Taiwanese patients with chronic genotype 2 hepatitis C virus infection | Liver International | 2016 | 28 |
| 40 | Social and Cultural Context of Betel Quid Consumption in Taiwan and Implications for Prevention and Cessation Interventions | Substance Use and Misuse | 2017 | 28 |
| 41 | Adiponectin attenuates kidney injury and fibrosis in deoxycorticosterone acetate-salt and angiotensin II-induced CKD mice | American Journal of Physiology - Renal Physiology | 2018 | 28 |
| 42 | Noninvasive assessment of liver fibrosis via spleen stiffness measurement using acoustic radiation force impulse sonoelastography in patients with chronic hepatitis B or C | Journal of Viral Hepatitis | 2012 | 27 |
| 43 | Adiponectin retards the progression of diabetic nephropathy in db/db mice by counteracting angiotensin II | Physiological Reports | 2014 | 27 |
| 44 | Systemic sclerosis increases the risks of deep vein thrombosis and pulmonary thromboembolism: a nationwide cohort study | Rheumatology | 2014 | 27 |
| 45 | Bufalin Inhibits NCI-H460 Human Lung Cancer Cell MetastasisIn Vitroby Inhibiting MAPKs, MMPs, and NF-κB Pathways | The American Journal of Chinese Medicine | 2015 | 27 |
| 46 | New methyl 5-(halomethyl)-1-aryl-1H-1,2,4-triazole-3-carboxylates as selective COX-2 inhibitors and anti-inflammatory agents: Design, synthesis, biological evaluation, and docking study | Bioorganic Chemistry | 2020 | 26 |
| 47 | Analysis of technique and patient survival over time in patients undergoing peritoneal dialysis | International Urology and Nephrology | 2016 | 25 |
| 48 | Splenectomy Correlates With Increased Risk of Pyogenic Liver Abscess: A Nationwide Cohort Study in Taiwan | Journal of Epidemiology | 2015 | 24 |
| 49 | Occurrence of Common Allergic Diseases in Children with Idiopathic Nephrotic Syndrome | Journal of Epidemiology | 2015 | 24 |
| 50 | Factors Associated with Lung Cancer Patients Refusing Treatment and Their Survival: A National Cohort Study under a Universal Health Insurance in Taiwan | PLoS ONE | 2014 | 24 |
