| # | Title | Journal | Year | Citations |
|---|
| 1 | Shear-induced endothelial mechanotransduction: the interplay between reactive oxygen species (ROS) and nitric oxide (NO) and the pathophysiological implications | Journal of Biomedical Science | 2014 | 245 |
| 2 | Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies | ACS Nano | 2021 | 189 |
| 3 | Oxidative stress-modulating drugs have preferential anticancer effects - involving the regulation of apoptosis, DNA damage, endoplasmic reticulum stress, autophagy, metabolism, and migration | Seminars in Cancer Biology | 2019 | 144 |
| 4 | Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals | Analytical Chemistry | 2016 | 139 |
| 5 | Natural Compounds from Herbs that can Potentially Execute as Autophagy Inducers for Cancer Therapy | International Journal of Molecular Sciences | 2017 | 113 |
| 6 | Oral Apomorphine Delivery from Solid Lipid Nanoparticles with Different Monostearate Emulsifiers: Pharmacokinetic and Behavioral Evaluations | Journal of Pharmaceutical Sciences | 2011 | 110 |
| 7 | Drug Repurposing Screening Identifies Tioconazole as an ATG4 Inhibitor that Suppresses Autophagy and Sensitizes Cancer Cells to Chemotherapy | Theranostics | 2018 | 106 |
| 8 | Analytical Measurement of PEGylated Molecules | Bioconjugate Chemistry | 2012 | 103 |
| 9 | Anticancer drugs for the modulation of endoplasmic reticulum stress and oxidative stress | Tumor Biology | 2015 | 96 |
| 10 | 1,4-Naphthoquinones: Some Biological Properties and Application | Chemical and Pharmaceutical Bulletin | 2020 | 95 |
| 11 | Golden Berry-Derived 4β-hydroxywithanolide E for Selectively Killing Oral Cancer Cells by Generating ROS, DNA Damage, and Apoptotic Pathways | PLoS ONE | 2013 | 94 |
| 12 | Global DNA methylation, DNMT1, and MBD2 in patients with rheumatoid arthritis | Immunology Letters | 2011 | 91 |
| 13 | Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress | BMC Complementary and Alternative Medicine | 2012 | 91 |
| 14 | Antifouling Compounds from Marine Macroalgae | Marine Drugs | 2017 | 89 |
| 15 | 4β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest | BMC Cancer | 2010 | 86 |
| 16 | Antiproliferation and Induction of Apoptosis in Ca9-22 Oral Cancer Cells by Ethanolic Extract of Gracilaria tenuistipitata | Molecules | 2012 | 86 |
| 17 | An Activity-Based Near-Infrared Glucuronide Trapping Probe for Imaging β-Glucuronidase Expression in Deep Tissues | Journal of the American Chemical Society | 2012 | 83 |
| 18 | DNA methylation, histone acetylation and methylation of epigenetic modifications as a therapeutic approach for cancers | Cancer Letters | 2016 | 82 |
| 19 | Cell damage and apoptosis in the hepatopancreas of Eriocheir sinensis induced by cadmium | Aquatic Toxicology | 2017 | 81 |
| 20 | Unfolded Protein Response (UPR) in Survival, Dormancy, Immunosuppression, Metastasis, and Treatments of Cancer Cells | International Journal of Molecular Sciences | 2019 | 81 |
| 21 | Effectiveness of wastewater treatment systems in removing microbial agents: a systematic review | Globalization and Health | 2020 | 80 |
| 22 | Recent progress in TGF-β inhibitors for cancer therapy | Biomedicine and Pharmacotherapy | 2021 | 77 |
| 23 | Combinational Polymorphisms of Seven CXCL12-Related Genes Are Protective against Breast Cancer in Taiwan | OMICS A Journal of Integrative Biology | 2009 | 70 |
| 24 | 6‐Mercaptopurine‐Induced Fluorescence Quenching of Monolayer MoS2 Nanodots: Applications to Glutathione Sensing, Cellular Imaging, and Glutathione‐Stimulated Drug Delivery | Advanced Functional Materials | 2017 | 69 |
| 25 | Withaferin A Induces Oxidative Stress-Mediated Apoptosis and DNA Damage in Oral Cancer Cells | Frontiers in Physiology | 2017 | 67 |
| 26 | Anti-metastatic activities of Antrodia camphorata against human breast cancer cells mediated through suppression of the MAPK signaling pathway | Food and Chemical Toxicology | 2011 | 66 |
| 27 | The interplay of autophagy and oxidative stress in the pathogenesis and therapy of retinal degenerative diseases | Cell and Bioscience | 2022 | 66 |
| 28 | Global variability in seawater Mg:Ca and Sr:Ca ratios in the modern ocean | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 62 |
| 29 | Screening strains for microbial biosorption technology of cadmium | Chemosphere | 2020 | 60 |
| 30 | Aqueous Extracts of the Edible Gracilaria tenuistipitata are Protective Against H2O2-Induced DNA Damage, Growth Inhibition, and Cell Cycle Arrest | Molecules | 2012 | 59 |
| 31 | Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy | Nature Communications | 2017 | 56 |
| 32 | Species delimitation with gene flow: A methodological comparison and population genomics approach to elucidate cryptic species boundaries in Malaysian Torrent Frogs | Molecular Ecology | 2017 | 56 |
| 33 | Detecting Epstein-Barr virus DNA from peripheral blood mononuclear cells in adult patients with systemic lupus erythematosus in Taiwan | Medical Microbiology and Immunology | 2005 | 52 |
| 34 | Synthesis and antiproliferative evaluation of 6-arylindeno[1,2-c]quinoline derivatives | Bioorganic and Medicinal Chemistry | 2009 | 52 |
| 35 | Global DNA methylation, DNMT1, and MBD2 in patients with systemic lupus erythematosus | Lupus | 2011 | 52 |
| 36 | Synthesis and antiproliferative evaluation of 3-phenylquinolinylchalcone derivatives against non-small cell lung cancers and breast cancers | European Journal of Medicinal Chemistry | 2013 | 52 |
| 37 | Identification of an iridium(III) complex with anti-bacterial and anti-cancer activity | Scientific Reports | 2015 | 52 |
| 38 | Quinacrine induces apoptosis in human leukemia K562 cells via p38 MAPK-elicited BCL2 down-regulation and suppression of ERK/c-Jun-mediated BCL2L1 expression | Toxicology and Applied Pharmacology | 2015 | 52 |
| 39 | Fern Plant–Derived Protoapigenone Leads to DNA Damage, Apoptosis, and G2/M Arrest in Lung Cancer Cell Line H1299 | DNA and Cell Biology | 2009 | 51 |
| 40 | Evaluation of Breast Cancer Susceptibility Using Improved Genetic Algorithms to Generate Genotype SNP Barcodes | IEEE/ACM Transactions on Computational Biology and Bioinformatics | 2013 | 50 |
| 41 | A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol | Nature Communications | 2017 | 50 |
| 42 | Lactobacillus acidophilus attenuates Salmonella-induced intestinal inflammation via TGF-β signaling | BMC Microbiology | 2015 | 48 |
| 43 | Tenuifolide B from Cinnamomum tenuifolium Stem Selectively Inhibits Proliferation of Oral Cancer Cells via Apoptosis, ROS Generation, Mitochondrial Depolarization, and DNA Damage | Toxins | 2016 | 48 |
| 44 | Assessing bisphenol A (BPA) exposure risk from long-term dietary intakes in Taiwan | Science of the Total Environment | 2016 | 48 |
| 45 | Role of Peptidergic Nerve Terminals in the Skin: Reversal of Thermal Sensation by Calcitonin Gene-Related Peptide in TRPV1-Depleted Neuropathy | PLoS ONE | 2012 | 47 |
| 46 | Preparation and Characterization of Naringenin-Loaded Elastic Liposomes for Topical Application | PLoS ONE | 2015 | 47 |
| 47 | Anemia risk in relation to lead exposure in lead-related manufacturing | BMC Public Health | 2017 | 47 |
| 48 | One-step mixing with humanized anti-mPEG bispecific antibody enhances tumor accumulation and therapeutic efficacy of mPEGylated nanoparticles | Biomaterials | 2014 | 45 |
| 49 | Concentration effects of grape seed extracts in anti-oral cancer cells involving differential apoptosis, oxidative stress, and DNA damage | BMC Complementary and Alternative Medicine | 2015 | 45 |
| 50 | Microemulsion formulation design and evaluation for hydrophobic compound: Catechin topical application | Colloids and Surfaces B: Biointerfaces | 2018 | 42 |
