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Top Articles

#TitleJournalYearCitations
1Improved binary PSO for feature selection using gene expression dataComputational Biology and Chemistry2008485
2Antiviral Natural Products and Herbal MedicinesJournal of Traditional and Complementary Medicine2014369
3Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteinsBiochemical and Biophysical Research Communications2014365
4Preparation, physicochemical characterization, and antioxidant effects of quercetin nanoparticlesInternational Journal of Pharmaceutics2008313
5Antiviral activity of Plantago major extracts and related compounds in vitroAntiviral Research2002251
6Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cellsCancer Letters2009251
7Curcumin Nanoparticles Improve the Physicochemical Properties of Curcumin and Effectively Enhance Its Antioxidant and Antihepatoma ActivitiesJournal of Agricultural and Food Chemistry2010233
8Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer propertiesCancer Cell International2013225
9Asiatic Acid, a Triterpene, Induces Apoptosis and Cell Cycle Arrest through Activation of Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Pathways in Human Breast Cancer CellsJournal of Pharmacology and Experimental Therapeutics2005207
10Naringenin-Loaded Nanoparticles Improve the Physicochemical Properties and the Hepatoprotective Effects of Naringenin in Orally-Administered Rats with CCl4-Induced Acute Liver FailurePharmaceutical Research2009197
11Antioxidant and Free Radical Scavenging Activities of Terminalia chebulaBiological and Pharmaceutical Bulletin2003195
12Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer A549 cellsLife Sciences2004191
13Influenza A (H1N1) Antiviral and Cytotoxic Agents from Ferula assa-foetidaJournal of Natural Products2009173
14Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entryBMC Microbiology2013162
15Comparison of 5-aminolevulinic acid-encapsulated liposome versus ethosome for skin delivery for photodynamic therapyInternational Journal of Pharmaceutics2008159
16The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell linesLife Sciences2002154
17Antiherpes simplex virus type 2 activity of casuarinin from the bark of Terminalia arjuna Linn.Antiviral Research2002153
18Hydrolyzable Tannins (Chebulagic Acid and Punicalagin) Target Viral Glycoprotein-Glycosaminoglycan Interactions To Inhibit Herpes Simplex Virus 1 Entry and Cell-to-Cell SpreadJournal of Virology2011149
19Recent research and development of Antrodia cinnamomea2013147
20Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytesScientific Reports2016146
21Andrographolide exerts anti‐hepatitis C virus activity by up‐regulating haeme oxygenase‐1 via the p38 MAPK/Nrf2 pathway in human hepatoma cellsBritish Journal of Pharmacology2014137
22The Influence of Type 2 Diabetes and Glucose-Lowering Therapies on Cancer Risk in the TaiwaneseExperimental Diabetes Research2012136
23Emodin-induced apoptosis through p53-dependent pathway in human hepatoma cellsLife Sciences2004130
24Chalcone inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosisFood and Chemical Toxicology2006125
25Nanoparticles formulation of Cuscuta chinensis prevents acetaminophen-induced hepatotoxicity in ratsFood and Chemical Toxicology2008125
26To use or not to use: an update on licit and illicit ketamine useSubstance Abuse and Rehabilitation2011118
27Water extract of licorice had anti-viral activity against human respiratory syncytial virus in human respiratory tract cell linesJournal of Ethnopharmacology2013112
28Apoptotic effects of extract from Antrodia camphorata fruiting bodies in human hepatocellular carcinoma cell linesCancer Letters2005110
29Oral Apomorphine Delivery from Solid Lipid Nanoparticles with Different Monostearate Emulsifiers: Pharmacokinetic and Behavioral EvaluationsJournal of Pharmaceutical Sciences2011110
30The in vitro activity of geraniin and 1,3,4,6-tetra-O-galloyl-β-d-glucose isolated from Phyllanthus urinaria against herpes simplex virus type 1 and type 2 infectionJournal of Ethnopharmacology2007108
31New Cytotoxic Cyclobutanoid Amides, a New Furanoid Lignan and Anti-Platelet Aggregation Constituents fromPiper arborescensPlanta Medica2005107
32Topical delivery of 5-aminolevulinic acid-encapsulated ethosomes in a hyperproliferative skin animal model using the CLSM technique to evaluate the penetration behaviorEuropean Journal of Pharmaceutics and Biopharmaceutics2009107
33An epigenetic modifier enhances the production of anti-diabetic and anti-inflammatory sesquiterpenoids from Aspergillus sydowiiBioorganic and Medicinal Chemistry2013105
34Carbon Dot-Mediated Synthesis of Manganese Oxide Decorated Graphene Nanosheets for Supercapacitor ApplicationACS Sustainable Chemistry and Engineering2016104
35Antileukemic Activity of Bidens pilosa L. var. minor (Blume) Sherff and Houttuynia cordata Thunb.The American Journal of Chinese Medicine2001101
36Acacetin-induced cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cellsCancer Letters200499
37Saikosaponin b2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entryJournal of Hepatology201599
38Increase of Bax/ Bcl-XL ratio and arrest of cell cycle by luteolin in immortalized human hepatoma cell lineLife Sciences200596
39Efficacy of Low-Molecular-Weight Fucoidan as a Supplemental Therapy in Metastatic Colorectal Cancer Patients: A Double-Blind Randomized Controlled TrialMarine Drugs201796
40Golden Berry-Derived 4β-hydroxywithanolide E for Selectively Killing Oral Cancer Cells by Generating ROS, DNA Damage, and Apoptotic PathwaysPLoS ONE201394
41Anti-Herpes Simplex Virus Activity of Bidens pilosa and Houttuynia cordataThe American Journal of Chinese Medicine200392
42The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A549 cellsLife Sciences200491
43Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stressBMC Complementary and Alternative Medicine201291
44Ensemble feature selection in medical datasets: Combining filter, wrapper, and embedded feature selection resultsExpert Systems202091
45Acacetin inhibits the proliferation of Hep G2 by blocking cell cycle progression and inducing apoptosisBiochemical Pharmacology200490
46Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolideInternational Journal of Nanomedicine201890
47Isoliquiritigenin induces apoptosis and cell cycle arrest through p53-dependent pathway in Hep G2 cellsLife Sciences200588
48Elastic liposomes as carriers for oral delivery and the brain distribution of (+)-catechinJournal of Drug Targeting201188
49Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 SignalingOxidative Medicine and Cellular Longevity201987
504β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrestBMC Cancer201086