# | Title | Journal | Year | Citations |
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1 | Improved binary PSO for feature selection using gene expression data | Computational Biology and Chemistry | 2008 | 485 |
2 | Antiviral Natural Products and Herbal Medicines | Journal of Traditional and Complementary Medicine | 2014 | 369 |
3 | Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins | Biochemical and Biophysical Research Communications | 2014 | 365 |
4 | Preparation, physicochemical characterization, and antioxidant effects of quercetin nanoparticles | International Journal of Pharmaceutics | 2008 | 313 |
5 | Antiviral activity of Plantago major extracts and related compounds in vitro | Antiviral Research | 2002 | 251 |
6 | Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells | Cancer Letters | 2009 | 251 |
7 | Curcumin Nanoparticles Improve the Physicochemical Properties of Curcumin and Effectively Enhance Its Antioxidant and Antihepatoma Activities | Journal of Agricultural and Food Chemistry | 2010 | 233 |
8 | Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties | Cancer Cell International | 2013 | 225 |
9 | Asiatic Acid, a Triterpene, Induces Apoptosis and Cell Cycle Arrest through Activation of Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Pathways in Human Breast Cancer Cells | Journal of Pharmacology and Experimental Therapeutics | 2005 | 207 |
10 | Naringenin-Loaded Nanoparticles Improve the Physicochemical Properties and the Hepatoprotective Effects of Naringenin in Orally-Administered Rats with CCl4-Induced Acute Liver Failure | Pharmaceutical Research | 2009 | 197 |
11 | Antioxidant and Free Radical Scavenging Activities of Terminalia chebula | Biological and Pharmaceutical Bulletin | 2003 | 195 |
12 | Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer A549 cells | Life Sciences | 2004 | 191 |
13 | Influenza A (H1N1) Antiviral and Cytotoxic Agents from Ferula assa-foetida | Journal of Natural Products | 2009 | 173 |
14 | Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entry | BMC Microbiology | 2013 | 162 |
15 | Comparison of 5-aminolevulinic acid-encapsulated liposome versus ethosome for skin delivery for photodynamic therapy | International Journal of Pharmaceutics | 2008 | 159 |
16 | The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines | Life Sciences | 2002 | 154 |
17 | Antiherpes simplex virus type 2 activity of casuarinin from the bark of Terminalia arjuna Linn. | Antiviral Research | 2002 | 153 |
18 | Hydrolyzable Tannins (Chebulagic Acid and Punicalagin) Target Viral Glycoprotein-Glycosaminoglycan Interactions To Inhibit Herpes Simplex Virus 1 Entry and Cell-to-Cell Spread | Journal of Virology | 2011 | 149 |
19 | Recent research and development of Antrodia cinnamomea | | 2013 | 147 |
20 | Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes | Scientific Reports | 2016 | 146 |
21 | Andrographolide exerts anti‐hepatitis C virus activity by up‐regulating haeme oxygenase‐1 via the p38 MAPK/Nrf2 pathway in human hepatoma cells | British Journal of Pharmacology | 2014 | 137 |
22 | The Influence of Type 2 Diabetes and Glucose-Lowering Therapies on Cancer Risk in the Taiwanese | Experimental Diabetes Research | 2012 | 136 |
23 | Emodin-induced apoptosis through p53-dependent pathway in human hepatoma cells | Life Sciences | 2004 | 130 |
24 | Chalcone inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis | Food and Chemical Toxicology | 2006 | 125 |
25 | Nanoparticles formulation of Cuscuta chinensis prevents acetaminophen-induced hepatotoxicity in rats | Food and Chemical Toxicology | 2008 | 125 |
26 | To use or not to use: an update on licit and illicit ketamine use | Substance Abuse and Rehabilitation | 2011 | 118 |
27 | Water extract of licorice had anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines | Journal of Ethnopharmacology | 2013 | 112 |
28 | Apoptotic effects of extract from Antrodia camphorata fruiting bodies in human hepatocellular carcinoma cell lines | Cancer Letters | 2005 | 110 |
29 | Oral Apomorphine Delivery from Solid Lipid Nanoparticles with Different Monostearate Emulsifiers: Pharmacokinetic and Behavioral Evaluations | Journal of Pharmaceutical Sciences | 2011 | 110 |
30 | The in vitro activity of geraniin and 1,3,4,6-tetra-O-galloyl-β-d-glucose isolated from Phyllanthus urinaria against herpes simplex virus type 1 and type 2 infection | Journal of Ethnopharmacology | 2007 | 108 |
31 | New Cytotoxic Cyclobutanoid Amides, a New Furanoid Lignan and Anti-Platelet Aggregation Constituents fromPiper arborescens | Planta Medica | 2005 | 107 |
32 | Topical delivery of 5-aminolevulinic acid-encapsulated ethosomes in a hyperproliferative skin animal model using the CLSM technique to evaluate the penetration behavior | European Journal of Pharmaceutics and Biopharmaceutics | 2009 | 107 |
33 | An epigenetic modifier enhances the production of anti-diabetic and anti-inflammatory sesquiterpenoids from Aspergillus sydowii | Bioorganic and Medicinal Chemistry | 2013 | 105 |
34 | Carbon Dot-Mediated Synthesis of Manganese Oxide Decorated Graphene Nanosheets for Supercapacitor Application | ACS Sustainable Chemistry and Engineering | 2016 | 104 |
35 | Antileukemic Activity of Bidens pilosa L. var. minor (Blume) Sherff and Houttuynia cordata Thunb. | The American Journal of Chinese Medicine | 2001 | 101 |
36 | Acacetin-induced cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells | Cancer Letters | 2004 | 99 |
37 | Saikosaponin b2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry | Journal of Hepatology | 2015 | 99 |
38 | Increase of Bax/ Bcl-XL ratio and arrest of cell cycle by luteolin in immortalized human hepatoma cell line | Life Sciences | 2005 | 96 |
39 | Efficacy of Low-Molecular-Weight Fucoidan as a Supplemental Therapy in Metastatic Colorectal Cancer Patients: A Double-Blind Randomized Controlled Trial | Marine Drugs | 2017 | 96 |
40 | Golden Berry-Derived 4β-hydroxywithanolide E for Selectively Killing Oral Cancer Cells by Generating ROS, DNA Damage, and Apoptotic Pathways | PLoS ONE | 2013 | 94 |
41 | Anti-Herpes Simplex Virus Activity of Bidens pilosa and Houttuynia cordata | The American Journal of Chinese Medicine | 2003 | 92 |
42 | The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A549 cells | Life Sciences | 2004 | 91 |
43 | Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress | BMC Complementary and Alternative Medicine | 2012 | 91 |
44 | Ensemble feature selection in medical datasets: Combining filter, wrapper, and embedded feature selection results | Expert Systems | 2020 | 91 |
45 | Acacetin inhibits the proliferation of Hep G2 by blocking cell cycle progression and inducing apoptosis | Biochemical Pharmacology | 2004 | 90 |
46 | Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide | International Journal of Nanomedicine | 2018 | 90 |
47 | Isoliquiritigenin induces apoptosis and cell cycle arrest through p53-dependent pathway in Hep G2 cells | Life Sciences | 2005 | 88 |
48 | Elastic liposomes as carriers for oral delivery and the brain distribution of (+)-catechin | Journal of Drug Targeting | 2011 | 88 |
49 | Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 Signaling | Oxidative Medicine and Cellular Longevity | 2019 | 87 |
50 | 4β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest | BMC Cancer | 2010 | 86 |