| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 2 | The EGF/hnRNP Q1 axis is involved in tumorigenesis via the regulation of cell cycle-related genes | Experimental and Molecular Medicine | 2018 | 547 |
| 3 | Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1 | Oncogene | 2017 | 454 |
| 4 | Nusinersen initiated in infants during the presymptomatic stage of spinal muscular atrophy: Interim efficacy and safety results from the Phase 2 NURTURE study | Neuromuscular Disorders | 2019 | 401 |
| 5 | Efficacy and Safety of Pegylated Interferon Combined with Ribavirin for the Treatment of Older Patients with Chronic Hepatitis C | Journal of Infectious Diseases | 2010 | 359 |
| 6 | Infections Caused by Carbapenem-Resistant Enterobacteriaceae: An Update on Therapeutic Options | Frontiers in Microbiology | 2019 | 313 |
| 7 | Adipocytokines and proinflammatory mediators from abdominal and epicardial adipose tissue in patients with coronary artery disease | International Journal of Obesity | 2008 | 300 |
| 8 | Rapid virological response and treatment duration for chronic hepatitis C genotype 1 patients: A randomized trial | Hepatology | 2008 | 299 |
| 9 | Symptoms of problematic cellular phone use, functional impairment and its association with depression among adolescents in Southern Taiwan | Journal of Adolescence | 2009 | 291 |
| 10 | The Associations Between Aggressive Behaviors and Internet Addiction and Online Activities in Adolescents | Journal of Adolescent Health | 2009 | 284 |
| 11 | New Insights into the Role of Inflammation in the Pathogenesis of Atherosclerosis | International Journal of Molecular Sciences | 2017 | 277 |
| 12 | Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction | Journal of Translational Medicine | 2011 | 270 |
| 13 | A randomised study of peginterferon and ribavirin for 16 versus 24 weeks in patients with genotype 2 chronic hepatitis C | Gut | 2007 | 257 |
| 14 | Psychiatric symptoms in adolescents with Internet addiction: Comparison with substance use | Psychiatry and Clinical Neurosciences | 2008 | 255 |
| 15 | Antiviral activity of Plantago major extracts and related compounds in vitro | Antiviral Research | 2002 | 251 |
| 16 | Standardization of Intraoperative Neuromonitoring of Recurrent Laryngeal Nerve in Thyroid Operation | World Journal of Surgery | 2010 | 241 |
| 17 | The precancer risk of betel quid chewing, tobacco use and alcohol consumption in oral leukoplakia and oral submucous fibrosis in southern Taiwan | British Journal of Cancer | 2003 | 236 |
| 18 | Epidemiology, impact and preventive care of chronic kidney disease in Taiwan | Nephrology | 2010 | 229 |
| 19 | Treatment of chronic hepatitis C in Asia: When East meets West | Journal of Gastroenterology and Hepatology (Australia) | 2009 | 227 |
| 20 | Psychometric Comparisons of 4 Measures for Assessing Upper-Extremity Function in People With Stroke | Physical Therapy | 2009 | 211 |
| 21 | Fresh ginger (Zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines | Journal of Ethnopharmacology | 2013 | 207 |
| 22 | Helium–Neon Laser Irradiation Stimulates Cell Proliferation through Photostimulatory Effects in Mitochondria | Journal of Investigative Dermatology | 2007 | 206 |
| 23 | Targeting B Cell Maturation Antigen (BCMA) in Multiple Myeloma: Potential Uses of BCMA-Based Immunotherapy | Frontiers in Immunology | 2018 | 205 |
| 24 | The characteristics of decision making, potential to take risks, and personality of college students with Internet addiction | Psychiatry Research | 2010 | 191 |
| 25 | Incidence, prevalence and mortality trends of dialysis end-stage renal disease in Taiwan from 1990 to 2001: the impact of national health insurance | Nephrology Dialysis Transplantation | 2008 | 190 |
| 26 | The Roles of MicroRNA in Lung Cancer | International Journal of Molecular Sciences | 2019 | 176 |
| 27 | Significant Predictive Factors for Prognosis of Primary Upper Urinary Tract Cancer after Radical Nephroureterectomy in Taiwanese Patients | European Urology | 2008 | 175 |
| 28 | Low-intensity Extracorporeal Shock Wave Treatment Improves Erectile Function: A Systematic Review and Meta-analysis | European Urology | 2017 | 173 |
| 29 | Green tea catechin enhances osteogenesis in a bone marrow mesenchymal stem cell line | Osteoporosis International | 2005 | 162 |
| 30 | The association between harmful alcohol use and Internet addiction among college students: Comparison of personality | Psychiatry and Clinical Neurosciences | 2009 | 162 |
| 31 | Multi‐dimensional discriminative factors for Internet addiction among adolescents regarding gender and age | Psychiatry and Clinical Neurosciences | 2009 | 162 |
| 32 | Hypoxic Lung-Cancer-Derived Extracellular Vesicle MicroRNA-103a Increases the Oncogenic Effects of Macrophages by Targeting PTEN | Molecular Therapy | 2018 | 155 |
| 33 | Early Improvement As a Predictor of Later Response to Antipsychotics in Schizophrenia: A Diagnostic Test Review | American Journal of Psychiatry | 2015 | 150 |
| 34 | Epidemiology and antimicrobial susceptibility profiles of Gram-negative bacteria causing urinary tract infections in the Asia-Pacific region: 2009–2010 results from the Study for Monitoring Antimicrobial Resistance Trends (SMART) | International Journal of Antimicrobial Agents | 2012 | 147 |
| 35 | Helium–Neon Laser Irradiation Stimulates Migration and Proliferation in Melanocytes and Induces Repigmentation in Segmental-Type Vitiligo | Journal of Investigative Dermatology | 2003 | 146 |
| 36 | Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes | Scientific Reports | 2016 | 146 |
| 37 | Impact of the clinical conditions at dialysis initiation on mortality in incident haemodialysis patients: a national cohort study in Taiwan | Nephrology Dialysis Transplantation | 2010 | 141 |
| 38 | 6-Shogaol, an Active Constituent of Dietary Ginger, Induces Autophagy by Inhibiting the AKT/mTOR Pathway in Human Non-Small Cell Lung Cancer A549 Cells | Journal of Agricultural and Food Chemistry | 2009 | 138 |
| 39 | Superoxide anion radical, lipid peroxides and antioxidant status in the blood of patients with breast cancer | Clinica Chimica Acta | 2005 | 137 |
| 40 | Andrographolide exerts anti‐hepatitis C virus activity by up‐regulating haeme oxygenase‐1 via the p38 MAPK/Nrf2 pathway in human hepatoma cells | British Journal of Pharmacology | 2014 | 137 |
| 41 | The sodium–glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure rats | Cardiovascular Diabetology | 2019 | 135 |
| 42 | Psychometric Comparisons of 3 Functional Ambulation Measures for Patients With Stroke | Stroke | 2010 | 134 |
| 43 | MALAT1 long non-coding RNA is overexpressed in multiple myeloma and may serve as a marker to predict disease progression | BMC Cancer | 2014 | 134 |
| 44 | Arctigenin, a dietary phytoestrogen, induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation | Free Radical Biology and Medicine | 2014 | 134 |
| 45 | Honokiol and Magnolol as Multifunctional Antioxidative Molecules for Dermatologic Disorders | Molecules | 2010 | 133 |
| 46 | Urban particulate matter down-regulates filaggrin via COX2 expression/PGE2 production leading to skin barrier dysfunction | Scientific Reports | 2016 | 131 |
| 47 | The importance of classification in sympathetic surgery and a proposed mechanism for compensatory hyperhidrosis: experience with 464 cases | Surgical Endoscopy and Other Interventional Techniques | 2006 | 130 |
| 48 | Anti-proliferative effect of apigenin and its apoptotic induction in human Hep G2 cells | Cancer Letters | 2006 | 129 |
| 49 | Hyperglycaemic conditions decrease cultured keratinocyte mobility: implications for impaired wound healing in patients with diabetes | British Journal of Dermatology | 2008 | 129 |
| 50 | Novel Biodegradable Porous Scaffold Applied to Skin Regeneration | PLoS ONE | 2013 | 128 |
