197(top 1%)
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Top Articles

#TitleJournalYearCitations
1EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: definition, characterization, and clinical implicationEuropace2016471
2Preferential blockade of presynaptic α-adrenoceptors by yohimbineEuropean Journal of Pharmacology1975454
3EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: Definition, characterization, and clinical implicationHeart Rhythm2017442
4Cellular and Molecular Mechanisms of Atrial Arrhythmogenesis in Patients With Paroxysmal Atrial FibrillationCirculation2014386
5Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial FibrillationCirculation2018376
6Postoperative atrial fibrillation: mechanisms, manifestations and managementNature Reviews Cardiology2019296
7Atrial Fibrillation Promotion by Endurance ExerciseJournal of the American College of Cardiology2013252
8Presynaptic receptor systems in catecholaminergic transmissionBiochemical Pharmacology1977236
9G-protein β3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia 1 ☆Gastroenterology2004225
10Molecular Basis of Atrial Fibrillation Pathophysiology and TherapyCirculation Research2020222
11Muscarinic receptors in the Mammalian HeartPharmacological Research2001217
12The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysisCardiovascular Research2016166
13Mutation E169K in Junctophilin-2 Causes Atrial Fibrillation Due to Impaired RyR2 StabilizationJournal of the American College of Cardiology2013165
14Ryanodine Receptor–Mediated Calcium Leak Drives Progressive Development of an Atrial Fibrillation Substrate in a Transgenic Mouse ModelCirculation2014160
15Enkephalin: A potential modulator of noradrenaline release in rat brainEuropean Journal of Pharmacology1976135
16MicroRNA Regulation and Cardiac Calcium SignalingCirculation Research2014117
17Role of inflammatory signaling in atrial fibrillationInternational Journal of Cardiology2019105
18COVID-19 associated atrial fibrillation: Incidence, putative mechanisms and potential clinical implicationsIJC Heart and Vasculature2020104
19Function and regulation of serine/threonine phosphatases in the healthy and diseased heartJournal of Molecular and Cellular Cardiology2013101
20Loss of MicroRNA-106b-25 Cluster Promotes Atrial Fibrillation by Enhancing Ryanodine Receptor Type-2 Expression and Calcium ReleaseCirculation: Arrhythmia and Electrophysiology2014101
21Sphingosine-1-phosphate and sphingosylphosphorylcholine constrict renal and mesenteric microvessels in vitroBritish Journal of Pharmacology200095
22Role of autonomic nervous system in atrial fibrillationInternational Journal of Cardiology201995
23EHRA/HRS/APHRS/SOLAECE expert consensus on Atrial cardiomyopathies: Definition, characterisation, and clinical implicationJournal of Arrhythmia201692
24Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived CardiomyocytesStem Cell Reports201892
25Fibroblast Inward-Rectifier Potassium Current Upregulation in Profibrillatory Atrial RemodelingCirculation Research201579
26Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial FibrillationFrontiers in Physiology201877
27Presynaptic α-adrenoceptorsGeneral Pharmacology197676
28Current controversies in determining the main mechanisms of atrial fibrillationJournal of Internal Medicine201676
29Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeuticsJournal of Physiology201776
30Atrial Fibrillation Activates AMP-Dependent Protein Kinase and its Regulation of Cellular Calcium HandlingJournal of the American College of Cardiology201575
31Somatostatin selectively inhibits noradrenaline release from hypothalamic neuronesNature198074
32Inverse remodelling of K2P3.1 K+channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapyEuropean Heart Journal201774
33Modulation of serotonin release in the brain via presynaptic receptorsTrends in Pharmacological Sciences198271
34Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studiesProgress in Biophysics and Molecular Biology202069
35Influence of drugs with affinity for α-adrenoceptors on noradrenaline release by potassium, tyramine and dimethylphenylpiperaziniumEuropean Journal of Pharmacology197468
36Coexistence of β1 and β2-Adrenoceptors in the Rabbit HeartJournal of Cardiovascular Pharmacology198268
37NLRP3 inflammasome is a key driver of obesity-induced atrial arrhythmiasCardiovascular Research202167
38Opportunities and Challenges for Drug Development: Public–Private Partnerships, Adaptive Designs and Big DataFrontiers in Pharmacology201660
39α-Adrenoceptors in the ventricular myocardium: clonidine, naphazoline and methoxamine as partial α-agonists exerting a competitive dualism in action to phenylephrineEuropean Journal of Pharmacology197657
40Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillationCardiovascular Research201456
41An update on atrial fibrillation in 2014: From pathophysiology to treatmentInternational Journal of Cardiology201656
42Calcium dysregulation in atrial fibrillation: the role of CaMKIIFrontiers in Pharmacology201455
43Computational models of atrial cellular electrophysiology and calcium handling, and their role in atrial fibrillationJournal of Physiology201654
44α-ADRENOCEPTORS MEDIATING POSITIVE INOTROPIC EFFECTS ON THE VENTRICULAR MYOCARDIUM: SOME ASPECTS OF STRUCTURE-ACTIVITY RELATIONSHIP OF SYMPATHOMIMETIC AMINESThe Japanese Journal of Pharmacology197653
45Cardiomyocyte Inflammasome Signaling in Cardiomyopathies and Atrial Fibrillation: Mechanisms and Potential Therapeutic ImplicationsFrontiers in Physiology201853
46JAK-STAT signalling and the atrial fibrillation promoting fibrotic substrateCardiovascular Research201752
47The contamination of valsartan and other sartans, part 1: New findingsJournal of Pharmaceutical and Biomedical Analysis201952
48Modulation of noradrenaline release in human saphenous vein via presynaptic α2-adrenoceptorsEuropean Journal of Pharmacology198451
49Thrombin receptor PAR4 drives canonical NLRP3 inflammasome signaling in the heartBasic Research in Cardiology202051
50The role of amiodarone in contemporary management of complex cardiac arrhythmiasPharmacological Research202050