# | Title | Journal | Year | Citations |
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1 | EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: definition, characterization, and clinical implication | Europace | 2016 | 471 |
2 | Preferential blockade of presynaptic α-adrenoceptors by yohimbine | European Journal of Pharmacology | 1975 | 454 |
3 | EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: Definition, characterization, and clinical implication | Heart Rhythm | 2017 | 442 |
4 | Cellular and Molecular Mechanisms of Atrial Arrhythmogenesis in Patients With Paroxysmal Atrial Fibrillation | Circulation | 2014 | 386 |
5 | Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation | Circulation | 2018 | 376 |
6 | Postoperative atrial fibrillation: mechanisms, manifestations and management | Nature Reviews Cardiology | 2019 | 296 |
7 | Atrial Fibrillation Promotion by Endurance Exercise | Journal of the American College of Cardiology | 2013 | 252 |
8 | Presynaptic receptor systems in catecholaminergic transmission | Biochemical Pharmacology | 1977 | 236 |
9 | G-protein β3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia 1 ☆ | Gastroenterology | 2004 | 225 |
10 | Molecular Basis of Atrial Fibrillation Pathophysiology and Therapy | Circulation Research | 2020 | 222 |
11 | Muscarinic receptors in the Mammalian Heart | Pharmacological Research | 2001 | 217 |
12 | The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis | Cardiovascular Research | 2016 | 166 |
13 | Mutation E169K in Junctophilin-2 Causes Atrial Fibrillation Due to Impaired RyR2 Stabilization | Journal of the American College of Cardiology | 2013 | 165 |
14 | Ryanodine Receptor–Mediated Calcium Leak Drives Progressive Development of an Atrial Fibrillation Substrate in a Transgenic Mouse Model | Circulation | 2014 | 160 |
15 | Enkephalin: A potential modulator of noradrenaline release in rat brain | European Journal of Pharmacology | 1976 | 135 |
16 | MicroRNA Regulation and Cardiac Calcium Signaling | Circulation Research | 2014 | 117 |
17 | Role of inflammatory signaling in atrial fibrillation | International Journal of Cardiology | 2019 | 105 |
18 | COVID-19 associated atrial fibrillation: Incidence, putative mechanisms and potential clinical implications | IJC Heart and Vasculature | 2020 | 104 |
19 | Function and regulation of serine/threonine phosphatases in the healthy and diseased heart | Journal of Molecular and Cellular Cardiology | 2013 | 101 |
20 | Loss of MicroRNA-106b-25 Cluster Promotes Atrial Fibrillation by Enhancing Ryanodine Receptor Type-2 Expression and Calcium Release | Circulation: Arrhythmia and Electrophysiology | 2014 | 101 |
21 | Sphingosine-1-phosphate and sphingosylphosphorylcholine constrict renal and mesenteric microvessels in vitro | British Journal of Pharmacology | 2000 | 95 |
22 | Role of autonomic nervous system in atrial fibrillation | International Journal of Cardiology | 2019 | 95 |
23 | EHRA/HRS/APHRS/SOLAECE expert consensus on Atrial cardiomyopathies: Definition, characterisation, and clinical implication | Journal of Arrhythmia | 2016 | 92 |
24 | Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes | Stem Cell Reports | 2018 | 92 |
25 | Fibroblast Inward-Rectifier Potassium Current Upregulation in Profibrillatory Atrial Remodeling | Circulation Research | 2015 | 79 |
26 | Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation | Frontiers in Physiology | 2018 | 77 |
27 | Presynaptic α-adrenoceptors | General Pharmacology | 1976 | 76 |
28 | Current controversies in determining the main mechanisms of atrial fibrillation | Journal of Internal Medicine | 2016 | 76 |
29 | Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics | Journal of Physiology | 2017 | 76 |
30 | Atrial Fibrillation Activates AMP-Dependent Protein Kinase and its Regulation of Cellular Calcium Handling | Journal of the American College of Cardiology | 2015 | 75 |
31 | Somatostatin selectively inhibits noradrenaline release from hypothalamic neurones | Nature | 1980 | 74 |
32 | Inverse remodelling of K2P3.1 K+channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapy | European Heart Journal | 2017 | 74 |
33 | Modulation of serotonin release in the brain via presynaptic receptors | Trends in Pharmacological Sciences | 1982 | 71 |
34 | Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies | Progress in Biophysics and Molecular Biology | 2020 | 69 |
35 | Influence of drugs with affinity for α-adrenoceptors on noradrenaline release by potassium, tyramine and dimethylphenylpiperazinium | European Journal of Pharmacology | 1974 | 68 |
36 | Coexistence of β1 and β2-Adrenoceptors in the Rabbit Heart | Journal of Cardiovascular Pharmacology | 1982 | 68 |
37 | NLRP3 inflammasome is a key driver of obesity-induced atrial arrhythmias | Cardiovascular Research | 2021 | 67 |
38 | Opportunities and Challenges for Drug Development: Public–Private Partnerships, Adaptive Designs and Big Data | Frontiers in Pharmacology | 2016 | 60 |
39 | α-Adrenoceptors in the ventricular myocardium: clonidine, naphazoline and methoxamine as partial α-agonists exerting a competitive dualism in action to phenylephrine | European Journal of Pharmacology | 1976 | 57 |
40 | Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation | Cardiovascular Research | 2014 | 56 |
41 | An update on atrial fibrillation in 2014: From pathophysiology to treatment | International Journal of Cardiology | 2016 | 56 |
42 | Calcium dysregulation in atrial fibrillation: the role of CaMKII | Frontiers in Pharmacology | 2014 | 55 |
43 | Computational models of atrial cellular electrophysiology and calcium handling, and their role in atrial fibrillation | Journal of Physiology | 2016 | 54 |
44 | α-ADRENOCEPTORS MEDIATING POSITIVE INOTROPIC EFFECTS ON THE VENTRICULAR MYOCARDIUM: SOME ASPECTS OF STRUCTURE-ACTIVITY RELATIONSHIP OF SYMPATHOMIMETIC AMINES | The Japanese Journal of Pharmacology | 1976 | 53 |
45 | Cardiomyocyte Inflammasome Signaling in Cardiomyopathies and Atrial Fibrillation: Mechanisms and Potential Therapeutic Implications | Frontiers in Physiology | 2018 | 53 |
46 | JAK-STAT signalling and the atrial fibrillation promoting fibrotic substrate | Cardiovascular Research | 2017 | 52 |
47 | The contamination of valsartan and other sartans, part 1: New findings | Journal of Pharmaceutical and Biomedical Analysis | 2019 | 52 |
48 | Modulation of noradrenaline release in human saphenous vein via presynaptic α2-adrenoceptors | European Journal of Pharmacology | 1984 | 51 |
49 | Thrombin receptor PAR4 drives canonical NLRP3 inflammasome signaling in the heart | Basic Research in Cardiology | 2020 | 51 |
50 | The role of amiodarone in contemporary management of complex cardiac arrhythmias | Pharmacological Research | 2020 | 50 |