| # | Title | Journal | Year | Citations |
|---|
| 1 | Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers | JAMA - Journal of the American Medical Association | 2017 | 1,898 |
| 2 | Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial | Lancet Oncology, The | 2017 | 1,376 |
| 3 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
| 4 | Large-scale genotyping identifies 41 new loci associated with breast cancer risk | Nature Genetics | 2013 | 960 |
| 5 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 6 | Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes | American Journal of Human Genetics | 2019 | 711 |
| 7 | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci | Nature Genetics | 2018 | 652 |
| 8 | Lung cancer susceptibility locus at 5p15.33 | Nature Genetics | 2008 | 514 |
| 9 | Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer | Nature Genetics | 2015 | 513 |
| 10 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer | Nature Genetics | 2013 | 493 |
| 11 | Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array | Nature Genetics | 2013 | 492 |
| 12 | Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma | Cell | 2019 | 430 |
| 13 | CHEK2 Is a Multiorgan Cancer Susceptibility Gene | American Journal of Human Genetics | 2004 | 426 |
| 14 | A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer | Nature Genetics | 2014 | 408 |
| 15 | Association of Type and Location ofBRCA1andBRCA2Mutations With Risk of Breast and Ovarian Cancer | JAMA - Journal of the American Medical Association | 2015 | 390 |
| 16 | Genome-wide association studies identify four ER negative–specific breast cancer risk loci | Nature Genetics | 2013 | 374 |
| 17 | Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer | Nature Genetics | 2014 | 360 |
| 18 | Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair | Nature Genetics | 2015 | 357 |
| 19 | Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer | Nature Genetics | 2017 | 356 |
| 20 | GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer | Nature Genetics | 2013 | 326 |
| 21 | A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 | Nature Genetics | 2010 | 321 |
| 22 | A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population | Nature Genetics | 2010 | 309 |
| 23 | Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer | Nature Genetics | 2017 | 289 |
| 24 | A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2 | Nature Genetics | 2009 | 276 |
| 25 | Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study | Nature Genetics | 2011 | 265 |
| 26 | Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses | Nature Genetics | 2020 | 265 |
| 27 | Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction | Nature Genetics | 2021 | 264 |
| 28 | Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer | JAMA Oncology | 2017 | 260 |
| 29 | Genome-wide association analysis identifies three new breast cancer susceptibility loci | Nature Genetics | 2012 | 256 |
| 30 | Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk | PLoS Genetics | 2013 | 244 |
| 31 | Common variants at 19p13 are associated with susceptibility to ovarian cancer | Nature Genetics | 2010 | 235 |
| 32 | Pathologic complete response to neoadjuvant cisplatin in BRCA1-positive breast cancer patients | Breast Cancer Research and Treatment | 2014 | 224 |
| 33 | Mutational spectrum in a worldwide study of 29,700 families withBRCA1orBRCA2mutations | Human Mutation | 2018 | 224 |
| 34 | Identification of six new susceptibility loci for invasive epithelial ovarian cancer | Nature Genetics | 2015 | 221 |
| 35 | Risk of Breast Cancer in Women With a CHEK2 Mutation With and Without a Family History of Breast Cancer | Journal of Clinical Oncology | 2011 | 207 |
| 36 | Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes | Nature Communications | 2020 | 196 |
| 37 | Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma | Cancer Cell | 2021 | 189 |
| 38 | A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer | Nature Genetics | 2018 | 184 |
| 39 | Results of a phase II open-label, non-randomized trial of cisplatin chemotherapy in patients with BRCA1-positive metastatic breast cancer | Breast Cancer Research | 2012 | 179 |
| 40 | PALB2,CHEK2andATMrare variants and cancer risk: data from COGS | Journal of Medical Genetics | 2016 | 174 |
| 41 | CA125 and Ovarian Cancer: A Comprehensive Review | Cancers | 2020 | 174 |
| 42 | Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 173 |
| 43 | A high proportion of founderBRCA1mutations in Polish breast cancer families | International Journal of Cancer | 2004 | 170 |
| 44 | Germline RECQL mutations are associated with breast cancer susceptibility | Nature Genetics | 2015 | 168 |
| 45 | Bilateral Oophorectomy and Breast Cancer Risk inBRCA1andBRCA2Mutation Carriers | Journal of the National Cancer Institute | 2017 | 160 |
| 46 | Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types | Cancer Discovery | 2016 | 157 |
| 47 | Selection criteria for genetic assessment of patients with familial melanoma | Journal of the American Academy of Dermatology | 2009 | 154 |
| 48 | Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts | BMJ: British Medical Journal | 2018 | 153 |
| 49 | Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium | Human Molecular Genetics | 2011 | 152 |
| 50 | Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers | European Urology | 2019 | 148 |
