| # | Title | Journal | Year | Citations |
|---|
| 1 | Divergent Effects of Serotonin on Coronary-Artery Dimensions and Blood Flow in Patients with Coronary Atherosclerosis and Control Patients | New England Journal of Medicine | 1991 | 677 |
| 2 | Chromosomal mapping of quantitative trait loci contributing to stroke in a rat model of complex human disease | Nature Genetics | 1996 | 237 |
| 3 | Do Changes of 6-Minute Walk Distance Predict Clinical Events in Patients With Pulmonary Arterial Hypertension? | Journal of the American College of Cardiology | 2012 | 222 |
| 4 | Abnormal sympathetic overactivity evoked by insulin in the skeletal muscle of patients with essential hypertension. | Journal of Clinical Investigation | 1992 | 217 |
| 5 | Does Carotid Intima-Media Thickness Regression Predict Reduction of Cardiovascular Events? | Journal of the American College of Cardiology | 2010 | 210 |
| 6 | Cardiac effects of long term thyrotropin-suppressive therapy with levothyroxine. | Journal of Clinical Endocrinology and Metabolism | 1993 | 201 |
| 7 | Effects of tissue factor induced by oxygen free radicals on coronary flow during reperfusion | Nature Medicine | 1996 | 171 |
| 8 | Local Effect of Serotonin Released during Coronary Angioplasty | New England Journal of Medicine | 1994 | 131 |
| 9 | Hereditary Deficiency of gp91 phox Is Associated With Enhanced Arterial Dilatation | Circulation | 2009 | 123 |
| 10 | Low glomerular filtration in the population: Prevalence, associated disorders, and awareness | Kidney International | 2006 | 122 |
| 11 | Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement | Journal of Nephrology | 2016 | 122 |
| 12 | Evidence for biventricular involvement in acromegaly: a Doppler echocardiographic study | European Heart Journal | 1993 | 116 |
| 13 | Diastolic Dysfunction in Patients with Non-insulin-dependent Diabetes Mellitus of Short Duration | Diabetic Medicine | 1996 | 102 |
| 14 | Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions | Annals of the Rheumatic Diseases | 2013 | 102 |
| 15 | Relation Between Diastolic Perfusion Time and Coronary Artery Stenosis During Stress-Induced Myocardial Ischemia | Circulation | 1995 | 99 |
| 16 | Antithrombotic Effects of Recombinant Human, Active Site–Blocked Factor VIIa in a Rabbit Model of Recurrent Arterial Thrombosis | Circulation Research | 1998 | 82 |
| 17 | Calcium channel blockers and cardiovascular outcomes: a meta-analysis of 175 634 patients | Journal of Hypertension | 2009 | 82 |
| 18 | A biochemical method for the quantitation of myocardial scarring after experimental coronary artery occlusion | Journal of Molecular and Cellular Cardiology | 1986 | 80 |
| 19 | Cardiovascular Effects of Histamine Infusion in Man | Journal of Cardiovascular Pharmacology | 1983 | 79 |
| 20 | Serum ?-L-fucosidase activity and early detection of hepatocellular carcinoma | | 1998 | 75 |
| 21 | Acute noradrenergic activation induces insulin resistance in human skeletal muscle | American Journal of Physiology - Endocrinology and Metabolism | 1994 | 71 |
| 22 | Serum lipoprotiens in four European communities: a quantitative comparison | European Journal of Clinical Investigation | 1978 | 68 |
| 23 | Carnitine improves peripheral glucose disposal in non-insulin-dependent diabetic patients | Diabetes Research and Clinical Practice | 1991 | 68 |
| 24 | Endothelium-derived relaxing factor modulates platelet aggregation in an in vivo model of recurrent platelet activation. | Circulation Research | 1992 | 68 |
| 25 | Population dietary salt reduction and the risk of cardiovascular disease. A scientific statement from the European Salt Action Network | Nutrition, Metabolism and Cardiovascular Diseases | 2019 | 68 |
| 26 | Cardiac ion channels and antihistamines: possible mechanisms of cardiotoxicity | Clinical and Experimental Allergy | 1999 | 63 |
| 27 | Monoclonal Antibody Against Tissue Factor Shortens Tissue Plasminogen Activator Lysis Time and Prevents Reocclusion in a Rabbit Model of Carotid Artery Thrombosis | Circulation | 1996 | 59 |
| 28 | NT-proBNP, IGF-I and survival in patients with chronic heart failure | Growth Hormone and IGF Research | 2007 | 51 |
| 29 | Recombinant human, active site-blocked factor VIIa reduces infarct size and no-reflow phenomenon in rabbits | American Journal of Physiology - Heart and Circulatory Physiology | 2000 | 49 |
| 30 | Insulin blunts sympathetic vasoconstriction through the alpha 2-adrenergic pathway in humans. | Hypertension | 1994 | 46 |
| 31 | Hepatic uptake and release of glucose, lactate, and amino acids in acutely uremic dogs | Metabolism: Clinical and Experimental | 1991 | 43 |
| 32 | Subcutaneous Immunoglobulin Replacement Therapy in Patients with Primary Immunodeficiency in Routine Clinical Practice: The VISPO Prospective Multicenter Study | Clinical Drug Investigation | 2015 | 43 |
| 33 | Expression of exogenous tissue factor pathway inhibitor in vivo suppresses thrombus formation in injured rabbit carotid arteries | Journal of the American College of Cardiology | 2001 | 37 |
| 34 | The arthritis of ulcerative colitis: clinical and genetic aspects | Journal of Rheumatology | 1992 | 36 |
| 35 | THE CLINICAL SPECTRUM OF PSORIATIC SPONDYLITIS | Rheumatology | 1988 | 34 |
| 36 | The treatment with growth hormone receptor antagonist in acromegaly: Effect on vascular structure and function in patients resistant to somatostatin analogues | Journal of Endocrinological Investigation | 2010 | 34 |
| 37 | Epinephrine directly antagonizes insulin-mediated activation of glucose uptake and inhibition of free fatty acid release in forearm tissues | Metabolism: Clinical and Experimental | 1992 | 33 |
| 38 | Short-term and long-term role of platelet activating factor as a mediator of in vivo platelet aggregation. | Circulation | 1993 | 33 |
| 39 | Inhibition of Leucocyte and Platelet Adhesion Reduces Neointimal Hyperplasia after Arterial Injury | Thrombosis and Haemostasis | 1997 | 31 |
| 40 | Insulin Modulation of Vascular Reactivity Is Already Impaired in Prehypertensive Spontaneously Hypertensive Rats | Hypertension | 1995 | 30 |
| 41 | Quantitation of Forearm Glucose and Free Fatty Acid (FFA) Disposal in Normal Subjects and Type II Diabetic Patients: Evidence Against an Essential Role for FFA in the Pathogenesis of Insulin Resistance* | Journal of Clinical Endocrinology and Metabolism | 1988 | 28 |
| 42 | Long-term growth hormone deficiency as a cause of cardiomyopathy and its reversibility with specific replacement therapy. | Journal of Clinical Endocrinology and Metabolism | 1996 | 27 |
| 43 | Acute effects of β-endorphin on cardiovascular function in patients with mild to moderate chronic heart failure | American Heart Journal | 2004 | 27 |
| 44 | Noninvasive Assessment of Systolic and Diastolic Function in 50 Patients with Friedreich’s Ataxia | Cardiology | 1988 | 24 |
| 45 | Endogenous prostaglandin endoperoxides may alter infarct size in the presence of thromboxane synthase inhibition: Studies in a rabbit model of coronary artery occlusion-reperfusion | Journal of the American College of Cardiology | 1993 | 24 |
| 46 | Age-related decrease of somatostatin receptor number in the normal human thymus | American Journal of Physiology - Endocrinology and Metabolism | 2000 | 24 |
| 47 | Evaluation, by Noninvasive Methods, of the Effects of Acute Loss of Thyroid Hormones on the Heart | Angiology | 1992 | 22 |
| 48 | Role of Tissue Factor Pathway Inhibitor in the Regulation of Tissue Factor‐Dependent Blood Coagulation | Cardiovascular Drug Reviews | 2002 | 22 |
| 49 | Looking for Myocardial Viability After a STICH Trial: Not Enough to Close the Door | Journal of Nuclear Medicine | 2012 | 21 |
| 50 | The Causal Role of Salt Depletion in Acute Renal Failure Due to Captopril in Hypertensive Patients with a Single Functioning Kidney and Renal Artery Stenosis | Renal Failure | 1987 | 20 |
