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Top Articles

#TitleJournalYearCitations
1Caspase-1 initiates apoptosis in the absence of gasdermin DNature Communications2019301
2Inflammasome‐associated cell death: Pyroptosis, apoptosis, and physiological implicationsMicrobiology and Immunology2020148
3Switching from Apoptosis to Pyroptosis: Gasdermin-Elicited Inflammation and Antitumor ImmunityInternational Journal of Molecular Sciences2021139
4Disease-associated mutations in CIAS1 induce cathepsin B–dependent rapid cell death of human THP-1 monocytic cellsBlood200797
5Pyroptotic cells externalize eat-me and release find-me signals and are efficiently engulfed by macrophagesInternational Immunology201393
6Anti-Inflammatory Activity of PYNOD and Its Mechanism in Humans and MiceJournal of Immunology201080
7Roles of the PI3K/Akt pathway and autophagy in TLR3 signaling-induced apoptosis and growth arrest of human prostate cancer cellsCancer Immunology, Immunotherapy201280
8Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomesCell Reports202167
9NLRP3 Mediates NF-κB Activation and Cytokine Induction in Microbially Induced and Sterile InflammationPLoS ONE201556
10Caspase-1 Protein Induces Apoptosis-associated Speck-like Protein Containing a Caspase Recruitment Domain (ASC)-mediated Necrosis Independently of Its Catalytic ActivityJournal of Biological Chemistry201150
11Mechanism and Repertoire of ASC-Mediated Gene ExpressionJournal of Immunology200940
12Caspase-8- and JNK-dependent AP-1 activation is required for Fas ligand-induced IL-8 productionFEBS Journal200735
13Caspase‐7 mediates caspase‐1‐induced apoptosis independently of BidMicrobiology and Immunology202026
14Activation of ASC induces apoptosis or necrosis, depending on the cell type, and causes tumor eradicationCancer Science201023
15Fas-associated factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 1International Immunology200620
16ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanismMucosal Immunology201916
17A human pathogenic bacterial infection model using the two-spotted cricket,Gryllus bimaculatusFEMS Microbiology Letters201613
18Pneumolysin-Dependent Calpain Activation and Interleukin-1α Secretion in Macrophages Infected with Streptococcus pneumoniaeInfection and Immunity201711
19Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spread of Listeria monocytogenes infection in macrophagesCell Death and Disease20219
20Gasdermin D‐independent release of interleukin‐1β by living macrophages in response to mycoplasmal lipoproteins and lipopeptidesImmunology20208
21Development of a Water-Soluble Indolylmaleimide Derivative IM-93 Showing Dual Inhibition of Ferroptosis and NETosisACS Medicinal Chemistry Letters20196
22Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansionCell Reports20225
23Characterization of Innate and Adaptive Immune Responses in PYNOD-Deficient MiceImmunoHorizons20182
24Involvement of p38MAPK in Impaired Neutrophil Bactericidal Activity of Hemodialysis PatientsTherapeutic Apheresis and Dialysis20181