| # | Title | Journal | Year | Citations |
|---|
| 1 | Monoclonal Antibody Pharmacokinetics and Pharmacodynamics | Clinical Pharmacology and Therapeutics | 2008 | 845 |
| 2 | Dietary flavonoids: Effects on xenobiotic and carcinogen metabolism | Toxicology in Vitro | 2006 | 773 |
| 3 | Pharmacodynamics of Vancomycin and Other Antimicrobials in Patients with Staphylococcus aureus Lower Respiratory Tract Infections | Clinical Pharmacokinetics | 2004 | 644 |
| 4 | Population Pharmacokinetics of Colistin Methanesulfonate and Formed Colistin in Critically Ill Patients from a Multicenter Study Provide Dosing Suggestions for Various Categories of Patients | Antimicrobial Agents and Chemotherapy | 2011 | 626 |
| 5 | International Consensus Guidelines for the Optimal Use of the Polymyxins: Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti‐infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP) | Pharmacotherapy | 2019 | 545 |
| 6 | General pharmacokinetic model for drugs exhibiting target-mediated drug disposition | Journal of Pharmacokinetics and Pharmacodynamics | 2001 | 501 |
| 7 | Cumulative Antibiotic Exposures Over Time and the Risk of Clostridium difficile Infection | Clinical Infectious Diseases | 2011 | 357 |
| 8 | Effects of the Flavonoids Biochanin A, Morin, Phloretin, and Silymarin on P-Glycoprotein-Mediated Transport | Journal of Pharmacology and Experimental Therapeutics | 2003 | 318 |
| 9 | Diversity of Mechanism-Based Pharmacodynamic Models | Drug Metabolism and Disposition | 2003 | 318 |
| 10 | Accessory Gene Regulator Group II Polymorphism in Methicillin-Resistant Staphylococcus aureus Is Predictive of Failure of Vancomycin Therapy | Clinical Infectious Diseases | 2004 | 315 |
| 11 | Mechanistic Determinants of Biotherapeutics Absorption Following SC Administration | AAPS Journal | 2012 | 253 |
| 12 | MicroRNAs Regulate CYP3A4 Expression via Direct and Indirect Targeting | Drug Metabolism and Disposition | 2009 | 236 |
| 13 | Flavonoid–drug interactions: Effects of flavonoids on ABC transporters | Life Sciences | 2006 | 226 |
| 14 | Quercetin pharmacokinetics in humans | Biopharmaceutics and Drug Disposition | 2008 | 207 |
| 15 | Clinical Pharmacokinetics of Non-Nucleoside Reverse Transcriptase Inhibitors | Clinical Pharmacokinetics | 2001 | 183 |
| 16 | Activity of Oral ALS-008176 in a Respiratory Syncytial Virus Challenge Study | New England Journal of Medicine | 2015 | 183 |
| 17 | Dosing guidance for intravenous colistin in critically-ill patients | Clinical Infectious Diseases | 2017 | 171 |
| 18 | Overview of the Proton-coupled MCT (SLC16A) Family of Transporters: Characterization, Function and Role in the Transport of the Drug of Abuse γ-Hydroxybutyric Acid | AAPS Journal | 2008 | 170 |
| 19 | Phase I and II Study of the Safety, Virologic Effect, and Pharmacokinetics/Pharmacodynamics of Single-Dose 3-O-(3′,3′-Dimethylsuccinyl)Betulinic Acid (Bevirimat) against Human Immunodeficiency Virus Infection | Antimicrobial Agents and Chemotherapy | 2007 | 164 |
| 20 | Linezolid‐Associated Peripheral and Optic Neuropathy, Lactic Acidosis, and Serotonin Syndrome | Pharmacotherapy | 2007 | 157 |
| 21 | Connectivity and stability of mesophotic coral reefs | Journal of Experimental Marine Biology and Ecology | 2011 | 156 |
| 22 | Pharmacokinetic/Pharmacodynamic Investigation of Colistin against Pseudomonas aeruginosa Using an In Vitro Model | Antimicrobial Agents and Chemotherapy | 2010 | 150 |
| 23 | Ampicillin Enhances Daptomycin- and Cationic Host Defense Peptide-Mediated Killing of Ampicillin- and Vancomycin-Resistant Enterococcus faecium | Antimicrobial Agents and Chemotherapy | 2012 | 150 |
| 24 | Updated US and European Dose Recommendations for Intravenous Colistin: How Do They Perform? | Clinical Infectious Diseases | 2016 | 145 |
| 25 | Applications of minimal physiologically-based pharmacokinetic models | Journal of Pharmacokinetics and Pharmacodynamics | 2012 | 144 |
| 26 | Effects of Methylphenidate on Fatigue and Depression: A Randomized, Double-Blind, Placebo-Controlled Trial | Journal of Pain and Symptom Management | 2012 | 144 |
| 27 | Modeling of Corticosteroid Pharmacogenomics in Rat Liver Using Gene Microarrays | Journal of Pharmacology and Experimental Therapeutics | 2003 | 135 |
| 28 | Dose Equivalency Evaluation of Major Corticosteroids: Pharmacokinetics and Cell Trafficking and Cortisol Dynamics | Journal of Clinical Pharmacology | 2003 | 132 |
| 29 | Nitric oxide neurotoxicity in neurodegenerative diseases | Frontiers in Bioscience - Landmark | 2004 | 132 |
| 30 | Reduction in endotoxemia, oxidative and inflammatory stress, and insulin resistance after Roux-en-Y gastric bypass surgery in patients with morbid obesity and type 2 diabetes mellitus | Surgery | 2012 | 126 |
| 31 | Pharmacodynamic modeling of time-dependent transduction systems | Clinical Pharmacology and Therapeutics | 2001 | 125 |
| 32 | Use of Pharmacokinetic-Pharmacodynamic Target Attainment Analyses To Support Phase 2 and 3 Dosing Strategies for Doripenem | Antimicrobial Agents and Chemotherapy | 2005 | 123 |
| 33 | Second-generation minimal physiologically-based pharmacokinetic model for monoclonal antibodies | Journal of Pharmacokinetics and Pharmacodynamics | 2013 | 123 |
| 34 | Inhibition of mitochondrial fragmentation protects against Alzheimer’s disease in rodent model | Human Molecular Genetics | 2017 | 123 |
| 35 | Pharmacokinetic and Pharmacodynamic Modeling of Recombinant Human Erythropoietin After Single and Multiple Doses in Healthy Volunteers | Journal of Clinical Pharmacology | 2004 | 122 |
| 36 | Psychedelic 5-Methoxy-N,N-Dimethyltryptamine: Metabolism, Pharmacokinetics, Drug Interactions, and Pharmacological Actions | Current Drug Metabolism | 2010 | 122 |
| 37 | Gender Differences in the Membrane Transport of Endogenous and Exogenous Compounds | Pharmacological Reviews | 2003 | 119 |
| 38 | The Influence of St. John's Wort on the Pharmacokinetics and Protein Binding of Imatinib Mesylate | Pharmacotherapy | 2004 | 119 |
| 39 | Combined Effects of Multiple Flavonoids on Breast Cancer Resistance Protein (ABCG2)-Mediated Transport | Pharmaceutical Research | 2004 | 119 |
| 40 | Attenuation of Colistin Bactericidal Activity by High Inoculum of Pseudomonas aeruginosa Characterized by a New Mechanism-Based Population Pharmacodynamic Model | Antimicrobial Agents and Chemotherapy | 2010 | 119 |
| 41 | Pharmacokinetic‐Pharmacodynamic Considerations in the Design of Hospital‐Acquired or Ventilator‐Associated Bacterial Pneumonia Studies: Look before You Leap! | Clinical Infectious Diseases | 2010 | 118 |
| 42 | Influence of molecular size on tissue distribution of antibody fragments | MAbs | 2016 | 117 |
| 43 | BIOCHEMICAL MECHANISM OF NITROGLYCERIN ACTION AND TOLERANCE: Is This Old Mystery Solved? | Annual Review of Pharmacology and Toxicology | 2004 | 115 |
| 44 | Effect of Flavonoids on MRP1-Mediated Transport in Panc-1 Cells | Journal of Pharmaceutical Sciences | 2003 | 114 |
| 45 | Scope of contemporary pharmacy practice: Roles, responsibilities, and functions of pharmacists and pharmacy technicians | Journal of the American Pharmacists Association: JAPhA | 2010 | 114 |
| 46 | Fifth-generation model for corticosteroid pharmacodynamics: application to steady-state receptor down-regulation and enzyme induction patterns during seven-day continuous infusion of methylprednisolone in rats | Journal of Pharmacokinetics and Pharmacodynamics | 2002 | 111 |
| 47 | Clinically Relevant Plasma Concentrations of Colistin in Combination with Imipenem Enhance Pharmacodynamic Activity against Multidrug-Resistant Pseudomonas aeruginosa at Multiple Inocula | Antimicrobial Agents and Chemotherapy | 2011 | 109 |
| 48 | Mechanistic considerations for the use of monoclonal antibodies for cancer therapy | Cancer Biology and Medicine | 2014 | 109 |
| 49 | Synergistic Killing of Multidrug-Resistant Pseudomonas aeruginosa at Multiple Inocula by Colistin Combined with Doripenem in an In Vitro Pharmacokinetic/Pharmacodynamic Model | Antimicrobial Agents and Chemotherapy | 2011 | 107 |
| 50 | Advanced glycation end products dietary restriction effects on bacterial gut microbiota in peritoneal dialysis patients; a randomized open label controlled trial | PLoS ONE | 2017 | 107 |
