| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 2 | A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement | Journal of Hepatology | 2020 | 2,171 |
| 3 | Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update | Hepatology International | 2016 | 1,908 |
| 4 | Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update | Hepatology International | 2017 | 1,537 |
| 5 | Large-scale association analysis identifies new risk loci for coronary artery disease | Nature Genetics | 2013 | 1,439 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 7 | Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma | Hepatology International | 2010 | 944 |
| 8 | Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update | Hepatology International | 2012 | 874 |
| 9 | Long-term entecavir therapy results in the reversal of fibrosis/cirrhosis and continued histological improvement in patients with chronic hepatitis B | Hepatology | 2010 | 840 |
| 10 | Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update | Hepatology International | 2008 | 832 |
| 11 | New trends on obesity and NAFLD in Asia | Journal of Hepatology | 2017 | 759 |
| 12 | Individual patient data meta-analysis of controlled attenuation parameter (CAP) technology for assessing steatosis | Journal of Hepatology | 2017 | 734 |
| 13 | Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19 | Science Immunology | 2020 | 689 |
| 14 | Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes | Nature Genetics | 2012 | 560 |
| 15 | Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis | Gut | 2013 | 497 |
| 16 | A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt | Liver International | 2011 | 481 |
| 17 | Normal serum aminotransferase concentration and risk of mortality from liver diseases: prospective cohort study | BMJ: British Medical Journal | 2004 | 477 |
| 18 | Mechanisms of acquired resistance to first- and second-generation EGFR tyrosine kinase inhibitors | Annals of Oncology | 2018 | 449 |
| 19 | Five-Year Survival Outcomes From the PACIFIC Trial: Durvalumab After Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer | Journal of Clinical Oncology | 2022 | 445 |
| 20 | Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue | Nature | 2000 | 424 |
| 21 | The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease | Hepatology International | 2020 | 422 |
| 22 | Asian diagnostic criteria for autoimmune pancreatitis: consensus of the Japan-Korea Symposium on Autoimmune Pancreatitis | Journal of Gastroenterology | 2008 | 418 |
| 23 | Metabolic Significance of Nonalcoholic Fatty Liver Disease in Nonobese, Nondiabetic Adults | Archives of Internal Medicine | 2004 | 373 |
| 24 | Asia–Pacific Working Party on Non‐alcoholic Fatty Liver Disease guidelines 2017—Part 1: Definition, risk factors and assessment | Journal of Gastroenterology and Hepatology (Australia) | 2018 | 358 |
| 25 | Oncogenic Pathway Combinations Predict Clinical Prognosis in Gastric Cancer | PLoS Genetics | 2009 | 354 |
| 26 | Oxaliplatin, fluorouracil, and leucovorin versus fluorouracil and leucovorin as adjuvant chemotherapy for locally advanced rectal cancer after preoperative chemoradiotherapy (ADORE): an open-label, multicentre, phase 2, randomised controlled trial | Lancet Oncology, The | 2014 | 336 |
| 27 | Risk assessment of hepatitis B virus-related hepatocellular carcinoma development using liver stiffness measurement (FibroScan) | Hepatology | 2011 | 329 |
| 28 | Entecavir Therapy for up to 96 Weeks in Patients With HBeAg-Positive Chronic Hepatitis B | Gastroenterology | 2007 | 324 |
| 29 | Four-Year Survival With Durvalumab After Chemoradiotherapy in Stage III NSCLC—an Update From the PACIFIC Trial | Journal of Thoracic Oncology | 2021 | 323 |
| 30 | Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission | The Lancet Gastroenterology and Hepatology | 2020 | 320 |
| 31 | Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone | International Journal of Obesity | 1997 | 318 |
| 32 | Gut commensal Bacteroides acidifaciens prevents obesity and improves insulin sensitivity in mice | Mucosal Immunology | 2017 | 310 |
| 33 | Use of Convalescent Plasma Therapy in Two COVID-19 Patients with Acute Respiratory Distress Syndrome in Korea | Journal of Korean Medical Science | 2020 | 283 |
| 34 | Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas) | Gut | 2016 | 274 |
| 35 | Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service | Diabetes and Metabolism Journal | 2016 | 269 |
| 36 | Durvalumab plus Gemcitabine and Cisplatin in Advanced Biliary Tract Cancer | Diabetes and Metabolism Journal | 2022 | 267 |
| 37 | CD44‐positive cells are responsible for gemcitabine resistance in pancreatic cancer cells | International Journal of Cancer | 2009 | 266 |
| 38 | The Prognosis and Survival Outcome of Intrahepatic Cholangiocarcinoma Following Surgical Resection: Association of Lymph Node Metastasis and Lymph Node Dissection with Survival | Annals of Surgical Oncology | 2009 | 265 |
| 39 | Sarcopaenia is associated with NAFLD independently of obesity and insulin resistance: Nationwide surveys (KNHANES 2008–2011) | Journal of Hepatology | 2015 | 264 |
| 40 | SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease | Nature Communications | 2020 | 263 |
| 41 | Sarcopenia is associated with significant liver fibrosis independently of obesity and insulin resistance in nonalcoholic fatty liver disease: Nationwide surveys (KNHANES 2008‐2011) | Hepatology | 2016 | 261 |
| 42 | Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway | Autophagy | 2015 | 252 |
| 43 | Preventative Effects of Rosiglitazone on Restenosis After Coronary Stent Implantation in Patients With Type 2 Diabetes | Diabetes Care | 2004 | 245 |
| 44 | Performance of Transient Elastography for the Staging of Liver Fibrosis in Patients with Chronic Hepatitis B: A Meta-Analysis | PLoS ONE | 2012 | 242 |
| 45 | Liver cancer: Approaching a personalized care | Journal of Hepatology | 2015 | 239 |
| 46 | Prognostic value of sarcopenia in patients with liver cirrhosis: A systematic review and meta-analysis | PLoS ONE | 2017 | 237 |
| 47 | Clinical characteristics and outcomes of Takayasu's arteritis: analysis of 108 patients using standardized criteria for diagnosis, activity assessment, and angiographic classification | Scandinavian Journal of Rheumatology | 2005 | 234 |
| 48 | Mechanisms of acquired resistance to first-line osimertinib: Preliminary data from the phase III FLAURA study | Annals of Oncology | 2018 | 229 |
| 49 | Validation of FIB-4 and comparison with other simple noninvasive indices for predicting liver fibrosis and cirrhosis in hepatitis B virus-infected patients | Liver International | 2010 | 225 |
| 50 | Acquired resistance to EGFR targeted therapy in non-small cell lung cancer: Mechanisms and therapeutic strategies | Cancer Treatment Reviews | 2018 | 225 |
