| # | Title | Journal | Year | Citations |
|---|
| 1 | Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity | Biochemical and Biophysical Research Communications | 1999 | 4,315 |
| 2 | Plasma Concentrations of a Novel, Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients | Arteriosclerosis, Thrombosis, and Vascular Biology | 2000 | 2,826 |
| 3 | Novel Modulator for Endothelial Adhesion Molecules | Circulation | 1999 | 2,042 |
| 4 | Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 | Nature Medicine | 2002 | 1,908 |
| 5 | Visfatin: A Protein Secreted by Visceral Fat That Mimics the Effects of Insulin | Science | 2005 | 1,694 |
| 6 | Suppression of Aging in Mice by the Hormone Klotho | Science | 2005 | 1,634 |
| 7 | Adiponectin, an Adipocyte-Derived Plasma Protein, Inhibits Endothelial NF-κB Signaling Through a cAMP-Dependent Pathway | Circulation | 2000 | 1,606 |
| 8 | Association of Hypoadiponectinemia With Coronary Artery Disease in Men | Arteriosclerosis, Thrombosis, and Vascular Biology | 2003 | 1,312 |
| 9 | Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages | Circulation | 2001 | 1,184 |
| 10 | Adiponectin and development of type 2 diabetes in the Pima Indian population | Lancet, The | 2002 | 1,001 |
| 11 | Circulating Concentrations of the Adipocyte Protein Adiponectin Are Decreased in Parallel With Reduced Insulin Sensitivity During the Progression to Type 2 Diabetes in Rhesus Monkeys | Diabetes | 2001 | 978 |
| 12 | Adiponectin Reduces Atherosclerosis in Apolipoprotein E-Deficient Mice | Circulation | 2002 | 963 |
| 13 | Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms | Nature Medicine | 2005 | 942 |
| 14 | Reciprocal Association of C-Reactive Protein With Adiponectin in Blood Stream and Adipose Tissue | Circulation | 2003 | 741 |
| 15 | Role of Adiponectin in Preventing Vascular Stenosis | Journal of Biological Chemistry | 2002 | 727 |
| 16 | Androgens Decrease Plasma Adiponectin, an Insulin-Sensitizing Adipocyte-Derived Protein | Diabetes | 2002 | 709 |
| 17 | Induction of Adiponectin, a Fat-Derived Antidiabetic and Antiatherogenic Factor, by Nuclear Receptors | Diabetes | 2003 | 685 |
| 18 | Adiponectin Stimulates Angiogenesis by Promoting Cross-talk between AMP-activated Protein Kinase and Akt Signaling in Endothelial Cells | Journal of Biological Chemistry | 2004 | 671 |
| 19 | Adiponectin as a Biomarker of the Metabolic Syndrome | Circulation Journal | 2004 | 663 |
| 20 | Adipocyte-Derived Plasma Protein Adiponectin Acts as a Platelet-Derived Growth Factor-BB–Binding Protein and Regulates Growth Factor–Induced Common Postreceptor Signal in Vascular Smooth Muscle Cell | Circulation | 2002 | 648 |
| 21 | Adiponectin-mediated modulation of hypertrophic signals in the heart | Nature Medicine | 2004 | 637 |
| 22 | Obesity, adiponectin and vascular inflammatory disease | Current Opinion in Lipidology | 2003 | 636 |
| 23 | A Novel Subtype of Type 1 Diabetes Mellitus Characterized by a Rapid Onset and an Absence of Diabetes-Related Antibodies | New England Journal of Medicine | 2000 | 614 |
| 24 | Selective Suppression of Endothelial Cell Apoptosis by the High Molecular Weight Form of Adiponectin | Circulation Research | 2004 | 581 |
| 25 | Adiponectin, Metabolic Risk Factors, and Cardiovascular Events among Patients with End-Stage Renal Disease | Journal of the American Society of Nephrology: JASN | 2002 | 560 |
| 26 | An Adipocyte-Derived Plasma Protein, Adiponectin, Adheres to Injured Vascular Walls | Hormone and Metabolic Research | 2000 | 528 |
| 27 | Plasma Adiponectin Concentration Is Associated With Skeletal Muscle Insulin Receptor Tyrosine Phosphorylation, and Low Plasma Concentration Precedes a Decrease in Whole-Body Insulin Sensitivity in Humans | Diabetes | 2002 | 491 |
| 28 | Adiponectin Specifically Increased Tissue Inhibitor of Metalloproteinase-1 Through Interleukin-10 Expression in Human Macrophages | Circulation | 2004 | 490 |
| 29 | Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin | Gastroenterology | 2003 | 447 |
| 30 | Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages | Blood | 2000 | 443 |
| 31 | Synthetic Peroxisome Proliferator-Activated Receptor- Agonist, Rosiglitazone, Increases Plasma Levels of Adiponectin in Type 2 Diabetic Patients | Diabetes Care | 2002 | 392 |
| 32 | Adiponectin: a key adipocytokine in metabolic syndrome | Clinical Science | 2006 | 377 |
| 33 | Association of Adiponectin Mutation With Type 2 Diabetes : A Candidate Gene for the Insulin Resistance Syndrome | Diabetes | 2002 | 356 |
| 34 | Genomic structure and mutations in adipose-specific gene, adiponectin | International Journal of Obesity | 2000 | 311 |
| 35 | Inflammatory Markers, Adiponectin, and Risk of Type 2 Diabetes in the Pima Indian | Diabetes Care | 2003 | 309 |
| 36 | Adiponectin Stimulates Angiogenesis in Response to Tissue Ischemia through Stimulation of AMP-activated Protein Kinase Signaling | Journal of Biological Chemistry | 2004 | 300 |
| 37 | Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma. A randomized controlled trial | British Journal of Cancer | 2001 | 295 |
| 38 | A New Simple Method for the Measurement of Visceral Fat Accumulation by Bioelectrical Impedance | Diabetes Care | 2005 | 285 |
| 39 | Fulminant Type 1 Diabetes: A nationwide survey in Japan | Diabetes Care | 2003 | 278 |
| 40 | From The Cover: Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 269 |
| 41 | Effect of Moderate Alcohol Consumption on Adiponectin, Tumor Necrosis Factor- , and Insulin Sensitivity | Diabetes Care | 2004 | 261 |
| 42 | The Pro12->Ala Substitution in PPAR- Is Associated With Resistance to Development of Diabetes in the General Population: Possible Involvement in Impairment of Insulin Secretion in Individuals With Type 2 Diabetes | Diabetes | 2001 | 230 |
| 43 | Coordinated Regulation of Fat-Specific and Liver-Specific Glycerol Channels, Aquaporin Adipose and Aquaporin 9 | Diabetes | 2002 | 225 |
| 44 | Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease | Gut | 2005 | 211 |
| 45 | Contribution of adipose tissue and de novo lipogenesis to nonalcoholic fatty liver disease | Journal of Clinical Investigation | 2005 | 211 |
| 46 | Aquaporin Adipose, a Putative Glycerol Channel in Adipocytes | Journal of Biological Chemistry | 2000 | 196 |
| 47 | The Endoplasmic Reticulum Chaperone Improves Insulin Resistance in Type 2 Diabetes | Diabetes | 2005 | 194 |
| 48 | Absence of c-kit gene mutations in gastrointestinal stromal tumours from neurofibromatosis type 1 patients | Journal of Pathology | 2004 | 188 |
| 49 | Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy | Aids | 2003 | 186 |
| 50 | Oxidized LDL–Induced NF-κB Activation and Subsequent Expression of Proinflammatory Genes Are Defective in Monocyte-Derived Macrophages From CD36-Deficient Patients | Arteriosclerosis, Thrombosis, and Vascular Biology | 2000 | 184 |
