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Top Articles

#TitleJournalYearCitations
1Roles of intestinal epithelial cells in the maintenance of gut homeostasisExperimental and Molecular Medicine2017448
2Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPasesNature2014416
3CCR7 Is Critically Important for Migration of Dendritic Cells in Intestinal Lamina Propria to Mesenteric Lymph NodesJournal of Immunology2006381
4IκBζ regulates TH17 development by cooperating with ROR nuclear receptorsNature2010361
5A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondiiImmunity2012311
6Interaction Between the Microbiota, Epithelia, and Immune Cells in the IntestineAnnual Review of Immunology2020294
7Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicidaNature Immunology2015291
8The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infectionNature Immunology2015291
9Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPSProceedings of the National Academy of Sciences of the United States of America2014289
10Probiotic Bifidobacterium breve Induces IL-10-Producing Tr1 Cells in the ColonPLoS Pathogens2012277
11Maintenance of intestinal homeostasis by mucosal barriersInflammation and Regeneration2018233
12A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3Journal of Experimental Medicine2009215
13Emerging roles of bile acids in mucosal immunity and inflammationMucosal Immunology2019192
14IL-6-STAT3 Controls Intracellular MHC Class II αβ Dimer Level through Cathepsin S Activity in Dendritic CellsImmunity2005191
15Current Views of Toll-Like Receptor Signaling PathwaysGastroenterology Research and Practice2010184
16Critical role of AIM2 in Mycobacterium tuberculosis infectionInternational Immunology2012178
17Lypd8 promotes the segregation of flagellated microbiota and colonic epitheliaNature2016167
18An Improved Method for High Quality Metagenomics DNA Extraction from Human and Environmental SamplesScientific Reports2016164
19Role of Gut Microbiota in Rheumatoid ArthritisJournal of Clinical Medicine2017164
20Smad2 and Smad3 Inversely Regulate TGF-β Autoinduction in Clostridium butyricum-Activated Dendritic CellsImmunity2015153
21NleC, a Type III Secretion Protease, Compromises NF-κB Activation by Targeting p65/RelAPLoS Pathogens2010147
22Cholesterol lowering: role in cancer prevention and treatmentBiological Chemistry2015147
23Critical Roles of a Dendritic Cell Subset Expressing a Chemokine Receptor, XCR1Journal of Immunology2013142
24GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolitesNature2019142
25Leptin acts as a growth factor for colorectal tumours at stages subsequent to tumour initiation in murine colon carcinogenesisGut2011134
26ATF6β is a host cellular target of the Toxoplasma gondii virulence factor ROP18Journal of Experimental Medicine2011133
27Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10International Immunology2010129
28Lipocalin 2-Dependent Inhibition of Mycobacterial Growth in Alveolar EpitheliumJournal of Immunology2008127
29Generation of colonic IgA-secreting cells in the caecal patchNature Communications2014121
30Two Mechanistically and Temporally Distinct NF-κB Activation Pathways in IL-1 SignalingScience Signaling2009116
31Dietary Folic Acid Promotes Survival of Foxp3+ Regulatory T Cells in the ColonJournal of Immunology2012114
32Quantitative spatial analysis of haematopoiesis-regulating stromal cells in the bone marrow microenvironment by 3D microscopyNature Communications2018109
33Host–microbiota interactions in rheumatoid arthritisExperimental and Molecular Medicine2019109
34The Role of Lipid Rafts in Cancer Cell Adhesion and MigrationInternational Journal of Cell Biology2012107
35Ifit1 Inhibits Japanese Encephalitis Virus Replication through Binding to 5′ Capped 2′-O Unmethylated RNAJournal of Virology2013106
36The Lactic Acid Bacterium Pediococcus acidilactici Suppresses Autoimmune Encephalomyelitis by Inducing IL-10-Producing Regulatory T CellsPLoS ONE2011104
37Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids fromCandida albicansInfection and Immunity200998
38Class-specific Regulation of Pro-inflammatory Genes by MyD88 Pathways and IκBζJournal of Biological Chemistry200896
39IL-15-Dependent Activation-Induced Cell Death-Resistant Th1 Type CD8αβ+NK1.1+ T Cells for the Development of Small Intestinal InflammationJournal of Immunology200295
40The innate immune response to Trypanosoma cruzi infectionMicrobes and Infection201095
41Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T CellsCell Reports201795
42The survival pathways phosphatidylinositol-3 kinase (PI3-K)/phosphoinositide-dependent protein kinase 1 (PDK1)/Akt modulate liver regeneration through hepatocyte size rather than proliferationHepatology200992
43Intestinal CX 3 C chemokine receptor 1 high (CX 3 CR1 high ) myeloid cells prevent T-cell-dependent colitisProceedings of the National Academy of Sciences of the United States of America201292
44The E2-Like Conjugation Enzyme Atg3 Promotes Binding of IRG and Gbp Proteins to Chlamydia- and Toxoplasma-Containing Vacuoles and Host ResistancePLoS ONE201490
45Enhanced Cancer Immunotherapy Using STAT3-Depleted Dendritic Cells with High Th1-Inducing Ability and Resistance to Cancer Cell-Derived Inhibitory FactorsJournal of Immunology201187
46Spi-B is critical for plasmacytoid dendritic cell function and developmentBlood201285
47Regulation of intestinal homeostasis by innate and adaptive immunityInternational Immunology201285
48Gut Microbiota–Derived Short-Chain Fatty Acids Promote Prostate Cancer Growth via IGF1 SignalingCancer Research202183
49Innate Immune Effectors in Mycobacterial InfectionClinical and Developmental Immunology201182
50IL-10-producing lung interstitial macrophages prevent neutrophilic asthmaInternational Immunology201682