| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity | Biochemical and Biophysical Research Communications | 1999 | 4,315 |
| 3 | Increased oxidative stress in obesity and its impact on metabolic syndrome | Journal of Clinical Investigation | 2004 | 4,302 |
| 4 | Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria | Cell | 2009 | 3,818 |
| 5 | Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species | Science | 2011 | 3,144 |
| 6 | Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia | Journal of Clinical Endocrinology and Metabolism | 2001 | 3,039 |
| 7 | Plasma Concentrations of a Novel, Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients | Arteriosclerosis, Thrombosis, and Vascular Biology | 2000 | 2,826 |
| 8 | The Role of Atg Proteins in Autophagosome Formation | Annual Review of Cell and Developmental Biology | 2011 | 2,587 |
| 9 | Novel Modulator for Endothelial Adhesion Molecules | Circulation | 1999 | 2,042 |
| 10 | Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 | Nature Medicine | 2002 | 1,908 |
| 11 | Bifidobacteria can protect from enteropathogenic infection through production of acetate | Nature | 2011 | 1,836 |
| 12 | Visfatin: A Protein Secreted by Visceral Fat That Mimics the Effects of Insulin | Science | 2005 | 1,694 |
| 13 | Suppression of Aging in Mice by the Hormone Klotho | Science | 2005 | 1,634 |
| 14 | Adiponectin, an Adipocyte-Derived Plasma Protein, Inhibits Endothelial NF-κB Signaling Through a cAMP-Dependent Pathway | Circulation | 2000 | 1,606 |
| 15 | PPAR Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein | Diabetes | 2001 | 1,591 |
| 16 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 17 | Autophagosomes form at ER–mitochondria contact sites | Nature | 2013 | 1,401 |
| 18 | Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer | JAMA Oncology | 2018 | 1,350 |
| 19 | Association of Hypoadiponectinemia With Coronary Artery Disease in Men | Arteriosclerosis, Thrombosis, and Vascular Biology | 2003 | 1,312 |
| 20 | Molecular definitions of autophagy and related processes | EMBO Journal | 2017 | 1,230 |
| 21 | Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages | Circulation | 2001 | 1,184 |
| 22 | The autophagosome: origins unknown, biogenesis complex | Nature Reviews Molecular Cell Biology | 2013 | 1,105 |
| 23 | Adipose Tissue Hypoxia in Obesity and Its Impact on Adipocytokine Dysregulation | Diabetes | 2007 | 1,048 |
| 24 | Weight Reduction Increases Plasma Levels of an Adipose-Derived Anti-Inflammatory Protein, Adiponectin | Journal of Clinical Endocrinology and Metabolism | 2001 | 1,023 |
| 25 | Adiponectin and development of type 2 diabetes in the Pima Indian population | Lancet, The | 2002 | 1,001 |
| 26 | Circulating Concentrations of the Adipocyte Protein Adiponectin Are Decreased in Parallel With Reduced Insulin Sensitivity During the Progression to Type 2 Diabetes in Rhesus Monkeys | Diabetes | 2001 | 978 |
| 27 | ATP drives lamina propria TH17 cell differentiation | Nature | 2008 | 970 |
| 28 | Adiponectin Reduces Atherosclerosis in Apolipoprotein E-Deficient Mice | Circulation | 2002 | 963 |
| 29 | Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer | Cell | 2002 | 957 |
| 30 | Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms | Nature Medicine | 2005 | 942 |
| 31 | The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism | Nature | 2005 | 888 |
| 32 | Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy | Molecular Cell | 2013 | 880 |
| 33 | Adiponectin Stimulates Production of Nitric Oxide in Vascular Endothelial Cells | Journal of Biological Chemistry | 2003 | 862 |
| 34 | Single-molecule imaging of EGFR signalling on the surface of living cells | Nature Cell Biology | 2000 | 816 |
| 35 | Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death | Journal of Cell Biology | 2004 | 775 |
| 36 | Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer | Nature Medicine | 2019 | 748 |
| 37 | Reciprocal Association of C-Reactive Protein With Adiponectin in Blood Stream and Adipose Tissue | Circulation | 2003 | 741 |
| 38 | Role of Adiponectin in Preventing Vascular Stenosis | Journal of Biological Chemistry | 2002 | 727 |
| 39 | Androgens Decrease Plasma Adiponectin, an Insulin-Sensitizing Adipocyte-Derived Protein | Diabetes | 2002 | 709 |
| 40 | Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus | Nature Genetics | 2008 | 694 |
| 41 | IL-6 in autoimmune disease and chronic inflammatory proliferative disease | Cytokine and Growth Factor Reviews | 2002 | 693 |
| 42 | Induction of Adiponectin, a Fat-Derived Antidiabetic and Antiatherogenic Factor, by Nuclear Receptors | Diabetes | 2003 | 685 |
| 43 | Adiponectin Stimulates Angiogenesis by Promoting Cross-talk between AMP-activated Protein Kinase and Akt Signaling in Endothelial Cells | Journal of Biological Chemistry | 2004 | 671 |
| 44 | Adiponectin as a Biomarker of the Metabolic Syndrome | Circulation Journal | 2004 | 663 |
| 45 | SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis | Nature | 2011 | 655 |
| 46 | Adipocyte-Derived Plasma Protein Adiponectin Acts as a Platelet-Derived Growth Factor-BB–Binding Protein and Regulates Growth Factor–Induced Common Postreceptor Signal in Vascular Smooth Muscle Cell | Circulation | 2002 | 648 |
| 47 | Two FOXP3+CD4+ T cell subpopulations distinctly control the prognosis of colorectal cancers | Nature Medicine | 2016 | 641 |
| 48 | Adiponectin-mediated modulation of hypertrophic signals in the heart | Nature Medicine | 2004 | 637 |
| 49 | Obesity, adiponectin and vascular inflammatory disease | Current Opinion in Lipidology | 2003 | 636 |
| 50 | Autophagy in major human diseases | EMBO Journal | 2021 | 615 |
