| # | Title | Journal | Year | Citations |
|---|
| 1 | In situ click chemistry generation of cyclooxygenase-2 inhibitors | Nature Communications | 2017 | 10,736 |
| 2 | Definition and classification of cancer cachexia: an international consensus | Lancet Oncology, The | 2011 | 4,015 |
| 3 | Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study | Lancet Oncology, The | 2008 | 2,357 |
| 4 | ESPEN guidelines on nutrition in cancer patients | Clinical Nutrition | 2017 | 1,855 |
| 5 | A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth | Cancer Cell | 2007 | 1,374 |
| 6 | Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study | Lancet Oncology, The | 2010 | 1,075 |
| 7 | Cancer-associated cachexia | Nature Reviews Disease Primers | 2018 | 908 |
| 8 | Sarcopenia With Limited Mobility: An International Consensus | Journal of the American Medical Directors Association | 2011 | 884 |
| 9 | ESPEN expert group recommendations for action against cancer-related malnutrition | Clinical Nutrition | 2017 | 758 |
| 10 | Understanding the mechanisms and treatment options in cancer cachexia | Nature Reviews Clinical Oncology | 2013 | 729 |
| 11 | Enzymatic Activity Associated with Class II HDACs Is Dependent on a Multiprotein Complex Containing HDAC3 and SMRT/N-CoR | Molecular Cell | 2002 | 663 |
| 12 | Occurrence, Causes, and Outcome of Delirium in Patients With Advanced Cancer | Archives of Internal Medicine | 2000 | 662 |
| 13 | Randomized Controlled Trial of Exercise Training in Postmenopausal Breast Cancer Survivors: Cardiopulmonary and Quality of Life Outcomes | Journal of Clinical Oncology | 2003 | 656 |
| 14 | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci | Nature Genetics | 2018 | 652 |
| 15 | Arsenic Binding to Proteins | Chemical Reviews | 2013 | 639 |
| 16 | Sarcopenia is associated with postoperative infection and delayed recovery from colorectal cancer resection surgery | British Journal of Cancer | 2012 | 634 |
| 17 | Metabolic Modulation of Glioblastoma with Dichloroacetate | Science Translational Medicine | 2010 | 606 |
| 18 | Geriatric assessment predicts survival and toxicities in elderly myeloma patients: an International Myeloma Working Group report | Blood | 2015 | 586 |
| 19 | Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer | British Journal of Cancer | 2008 | 563 |
| 20 | XRCC1 Stimulates Human Polynucleotide Kinase Activity at Damaged DNA Termini and Accelerates DNA Single-Strand Break Repair | Cell | 2001 | 554 |
| 21 | Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia | Nature | 2014 | 515 |
| 22 | Nucleoside analogues and nucleobases in cancer treatment | Lancet Oncology, The | 2002 | 494 |
| 23 | Measurement of skeletal muscle radiation attenuation and basis of its biological variation | Acta Physiologica | 2014 | 489 |
| 24 | Body Composition as an Independent Determinant of 5-Fluorouracil–Based Chemotherapy Toxicity | Clinical Cancer Research | 2007 | 485 |
| 25 | ESPEN practical guideline: Clinical Nutrition in cancer | Clinical Nutrition | 2021 | 472 |
| 26 | Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet Oncology, The | 2017 | 451 |
| 27 | The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies | Clinical and Translational Radiation Oncology | 2018 | 415 |
| 28 | Sarcopenia: A Time for Action. An SCWD Position Paper | Journal of Cachexia, Sarcopenia and Muscle | 2019 | 410 |
| 29 | Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer | British Journal of Cancer | 2011 | 402 |
| 30 | Low body mass index and sarcopenia associated with dose-limiting toxicity of sorafenib in patients with renal cell carcinoma | Annals of Oncology | 2010 | 379 |
| 31 | Body composition in patients with non−small cell lung cancer: a contemporary view of cancer cachexia with the use of computed tomography image analysis | American Journal of Clinical Nutrition | 2010 | 377 |
| 32 | Phase III Trial Comparing Radical Radiotherapy With and Without Cisplatin Chemotherapy in Patients With Advanced Squamous Cell Cancer of the Cervix | Journal of Clinical Oncology | 2002 | 376 |
| 33 | Targeted delivery of nanoparticles for the treatment of lung diseases | Advanced Drug Delivery Reviews | 2008 | 375 |
| 34 | Mitotic Transcription Repression in Vivo in the Absence of Nucleosomal Chromatin Condensation | Journal of Cell Biology | 2000 | 372 |
| 35 | Validity of the McGill Quality of Life Questionnaire in the palliative care setting: a multi-centre Canadian study demonstrating the importance of the existential domain | Palliative Medicine | 1997 | 358 |
| 36 | Invadopodia Are Required for Cancer Cell Extravasation and Are a Therapeutic Target for Metastasis | Cell Reports | 2014 | 310 |
| 37 | Emerging Transporters of Clinical Importance: An Update From the International Transporter Consortium | Clinical Pharmacology and Therapeutics | 2013 | 307 |
| 38 | Nucleoside transporters: molecular biology and implications for therapeutic development | Trends in Molecular Medicine | 1999 | 303 |
| 39 | RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites | EMBO Journal | 2012 | 302 |
| 40 | COVID-19 and Bangladesh: Challenges and How to Address Them | Frontiers in Public Health | 2020 | 299 |
| 41 | A Multicenter Study Comparing Two Numerical Versions of the Edmonton Symptom Assessment System in Palliative Care Patients | Journal of Pain and Symptom Management | 2011 | 290 |
| 42 | Randomized Controlled Trial of the Effects of Print Materials and Step Pedometers on Physical Activity and Quality of Life in Breast Cancer Survivors | Journal of Clinical Oncology | 2007 | 289 |
| 43 | Prognostic Significance of Human Epidermal Growth Factor Receptor Positivity for the Development of Brain Metastasis After Newly Diagnosed Breast Cancer | Journal of Clinical Oncology | 2006 | 288 |
| 44 | Effects of presurgical exercise training on cardiorespiratory fitness among patients undergoing thoracic surgery for malignant lung lesions | Cancer | 2007 | 280 |
| 45 | Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy | Oncogene | 2003 | 267 |
| 46 | Palbociclib plus letrozole as first-line therapy in estrogen receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer with extended follow-up | Breast Cancer Research and Treatment | 2019 | 265 |
| 47 | Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction | Nature Genetics | 2021 | 264 |
| 48 | Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta | Biochemical Journal | 1997 | 258 |
| 49 | BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair | Journal of Cell Biology | 2010 | 240 |
| 50 | Computed tomography-defined muscle and fat wasting are associated with cancer clinical outcomes | Seminars in Cell and Developmental Biology | 2016 | 227 |
