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Top Articles

#TitleJournalYearCitations
1In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing CytokinesJournal of Experimental Medicine20021,069
2Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual diseaseLeukemia19991,038
3Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhoodLancet, The1998876
4Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancyClinical Endocrinology1999863
5The Role of Helper T Cell Products in Mouse B Cell Differentiation and Isotype RegulationImmunological Reviews1988754
6Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infectionNature Medicine2000384
7Mice Lacking the MHC Class II Transactivator (CIITA) Show Tissue-Specific Impairment of MHC Class II ExpressionImmunity1996344
8Premature Ovarian Failure and Ovarian Autoimmunity*Endocrine Reviews1997331
9Primers and protocols for standardized detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin and T cell receptor gene rearrangements and TAL1 deletions as PCR targets Report of the BIOMED-1 CONCERTED ACTION: Investigation of minimal residual disease in acute leukemiaLeukemia1999328
10Markers of mouse macrophage development detected by monoclonal antibodiesJournal of Immunological Methods1994326
11Immunohistochemical Characterization of Monocytes-Macrophages and Dendritic Cells Involved in the Initiation of the Insulitis and β-Cell Destruction in NOD MiceDiabetes1994305
12Strain-dependent induction of cytokine profiles in the gut by orally administered Lactobacillus strainsVaccine2000279
13Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytesNature1995268
14Molecular and flow cytometric analysis of the Vβ repertoire for clonality assessment in mature TCRαβ T-cell proliferationsBlood2001230
15Survival and outcome in 73 anti-Hu positive patients with paraneoplastic encephalomyelitis/sensory neuronopathyJournal of Neurology2002224
16High rate of autoimmune thyroiditis in bipolar disorder: lack of association with lithium exposureBiological Psychiatry2002220
17Minimal residual disease in leukaemia patientsLancet Oncology, The2001217
18Analysis of immunoglobulin and T cell receptor genes. Part I: Basic and technical aspectsClinica Chimica Acta1991214
191-alpha,25-Dihydroxyvitamin D3 (1,25(OH)(2)D(3)) hampers the maturation of fully active immature dendritic cells from monocytesEuropean Journal of Endocrinology2001209
20Analysis of immunoglobulin and T cell receptor genes. Part II: Possibilities and limitations in the diagnosis and management of lymphoproliferative diseases and related disordersClinica Chimica Acta1991208
21Heterogeneity of mouse spleen dendritic cells: in vivo phagocytic activity, expression of macrophage markers, and subpopulation turnoverJournal of Immunology1998206
22Heterogeneity of Mouse Spleen Dendritic Cells: In Vivo Phagocytic Activity, Expression of Macrophage Markers, and Subpopulation TurnoverJournal of Immunology1998206
23The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stagesEuropean Journal of Immunology1993199
24E2A and EBF Act in Synergy with the V(D)J Recombinase to Generate a Diverse Immunoglobulin Repertoire in Nonlymphoid CellsMolecular Cell2000192
25Stepwise development of thymic microenvironments in vivo is regulated by thymocyte subsetsDevelopment (Cambridge)2000188
26Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymusEuropean Journal of Immunology1999176
27Disorganization and restoration of thymic medullary epithelial cells in T cell receptor-negative scid mice: Evidence that receptor-bearing lymphocytes influence maturation of the thymic microenvironmentEuropean Journal of Immunology1991172
28Glucocorticoids: mechanisms of action and anti-inflammatory potential in asthmaMediators of Inflammation1998157
29Cross-lineage T cell receptor gene rearrangements occur in more than ninety percent of childhood precursor-B acute lymphoblastic leukemias: alternative PCR targets for detection of minimal residual diseaseLeukemia1999156
30Comparative analysis of Ig and TCR gene rearrangements at diagnosis and at relapse of childhood precursor-B–ALL provides improved strategies for selection of stable PCR targets for monitoring of minimal residual diseaseBlood2002155
31Detection of minimal residual disease identifies differences in treatment response between T-ALL and precursor B-ALLBlood2002150
32Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerantScience1989140
33Serum anti-GQ1bIgG antibodies recognize surface epitopes onCampylobacter jejunifrom patients with Miller Fisher syndromeAnnals of Neurology1995137
34Defective maturation and function of antigen-presenting cells in type 1 diabetesLancet, The1995135
35The Same IκBα Mutation in Two Related Individuals Leads to Completely Different Clinical SyndromesJournal of Experimental Medicine2004135
36Serum immunoglobulin levels and naturally occurring antibodies against carbohydrate antigens in germ-free BALB/c mice fed chemically defined ultrafiltered dietEuropean Journal of Immunology1989134
37Pericytes and periendothelial cells of brain parenchyma vessels co-express aminopeptidase N, aminopeptidase A, and nestinJournal of Neuroscience Research1999129
38Thymic microenvironments, 3-D versus 2-D?Seminars in Immunology1999128
39Critical illness polyneuropathy and myopathy (CIPNM): evidence for local immune activation by cytokine-expression in the muscle tissueJournal of Neuroimmunology2000128
40BIOMED-1 concerted action report: flow cytometric immunophenotyping of precursor B-ALL with standardized triple-stainingsLeukemia2001128
41Distinct mouse bone marrow macrophage precursors identified by differential expression of ER-MP12 and ER-MP20 antigensEuropean Journal of Immunology1994127
42Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.Journal of Experimental Medicine1993125
43Acute myeloid leukemia M4 with bone marrow eosinophilia (M4Eo) and inv(16)(p13q22) exhibits a specific immunophenotype with CD2 expressionBlood1993124
44Ig Heavy Chain Gene Rearrangements in T-Cell Acute Lymphoblastic Leukemia Exhibit Predominant Dh6-19 and Dh7-27 Gene Usage, Can Result in Complete V-D-J Rearrangements, and Are Rare in T-Cell Receptor β LineageBlood1999124
45Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targets for detection of minimal residual disease by real-time quantitative PCRLeukemia2002120
46Are Intestinal bacteria involved in the etiology of rheumatoid arthritis?Apmis1992114
47BIOMED-1 Concerted Action report: Flow cytometric characterization of CD7+ cell subsets in normal bone marrow as a basis for the diagnosis and follow-up of T cell acute lymphoblastic leukemia (T-ALL)Leukemia2000104
48Longitudinal Survey of Lymphocyte Subpopulations in the First Year of LifePediatric Research2000103
49The Obligate Anaerobic Faecal Flora of Patients with Crohn's Disease and Their First-Degree RelativesScandinavian Journal of Gastroenterology1988102
50Characterization of the translocation breakpoint sequences of twoDEK-CAN fusion genes present in t(6;9) acute myeloid leukemia and aSET-CAN fusion gene found in a case of acute undifferentiated leukemiaGenes Chromosomes and Cancer1992102