# | Title | Journal | Year | Citations |
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1 | A single ataxia telangiectasia gene with a product similar to PI-3 kinase | Science | 1995 | 2,634 |
2 | Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22 | Cell | 1984 | 1,552 |
3 | Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms | Nature | 1999 | 1,317 |
4 | A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia | Nature | 1982 | 1,313 |
5 | Interacting Molecular Loops in the Mammalian Circadian Clock | Science | 2000 | 1,223 |
6 | Looping and Interaction between Hypersensitive Sites in the Active β-globin Locus | Molecular Cell | 2002 | 1,205 |
7 | Chromosomal stability and the DNA double-stranded break connection | Nature Reviews Genetics | 2001 | 1,049 |
8 | The DNA Double-Strand Break Repair Gene hMRE11 Is Mutated in Individuals with an Ataxia-Telangiectasia-like Disorder | Cell | 1999 | 986 |
9 | Molecular mechanism of nucleotide excision repair | Genes and Development | 1999 | 978 |
10 | Structural organization of the bcr gene and its role in the Ph′ translocation | Nature | 1985 | 871 |
11 | Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia | Nature | 1983 | 848 |
12 | Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair | Molecular Cell | 1998 | 796 |
13 | DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor | Science | 1993 | 791 |
14 | Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia | Nature | 1983 | 723 |
15 | Sequential Assembly of the Nucleotide Excision Repair Factors In Vivo | Molecular Cell | 2001 | 712 |
16 | ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes | Cell | 1992 | 698 |
17 | Localization of an ataxia-telangiectasia gene to chromosome 11q22–23 | Nature | 1988 | 677 |
18 | Nucleotide excision repair and human syndromes | Carcinogenesis | 2000 | 610 |
19 | Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene | Nature | 1995 | 531 |
20 | p53 modulation of TFIIH–associated nucleotide excision repair activity | Nature Genetics | 1995 | 525 |
21 | Runx1 Expression Marks Long-Term Repopulating Hematopoietic Stem Cells in the Midgestation Mouse Embryo | Immunity | 2002 | 523 |
22 | Premature Aging in Mice Deficient in DNA Repair and Transcription | Science | 2002 | 509 |
23 | Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo | EMBO Journal | 2000 | 507 |
24 | Xeroderma Pigmentosum Group F Caused by a Defect in a Structure-Specific DNA Repair Endonuclease | Cell | 1996 | 492 |
25 | Repair of DNA interstrand cross-links | Mutation Research DNA Repair | 2001 | 490 |
26 | Role of PML in Cell Growth and the Retinoic Acid Pathway | Science | 1998 | 488 |
27 | Transcription complex stability and chromatin dynamics in vivo | Nature | 1995 | 469 |
28 | Human Rad50/Mre11 Is a Flexible Complex that Can Tether DNA Ends | Molecular Cell | 2001 | 437 |
29 | Hematopoietic Stem Cells Localize to the Endothelial Cell Layer in the Midgestation Mouse Aorta | Immunity | 2002 | 428 |
30 | Molecular Mechanisms of the Biological Clock in Cultured Fibroblasts | Science | 2001 | 426 |
31 | Disruption of Mouse RAD54 Reduces Ionizing Radiation Resistance and Homologous Recombination | Cell | 1997 | 403 |
32 | Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia | Cell | 1987 | 400 |
33 | HbVar: A relational database of human hemoglobin variants and thalassemia mutations at the globin gene server | Human Mutation | 2002 | 400 |
34 | Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene. | Molecular and Cellular Biology | 1992 | 368 |
35 | The transcription factor GATA6 is essential for early extraembryonic development | Development (Cambridge) | 1999 | 364 |
36 | A temperature-sensitive disorder in basal transcription and DNA repair in humans | Nature Genetics | 2001 | 362 |
37 | Bicaudal-D regulates COPI-independent Golgi–ER transport by recruiting the dynein–dynactin motor complex | Nature Cell Biology | 2002 | 357 |
38 | Photic Induction of mPer1 and mPer2 in Cry-Deficient Mice Lacking a Biological Clock | Science | 1999 | 348 |
39 | The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA. | Molecular and Cellular Biology | 1992 | 339 |
40 | Spatial organization of gene expression: the active chromatin hub | Chromosome Research | 2003 | 336 |
41 | Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence | Current Biology | 1997 | 335 |
42 | Molecular characterization of the human excision repair gene : cDNA cloning and amino acid homology with the yeast DNA repair gene | Cell | 1986 | 334 |
43 | ATP-Dependent Chromatin Remodeling by the Cockayne Syndrome B DNA Repair-Transcription-Coupling Factor | Molecular and Cellular Biology | 2000 | 334 |
44 | Intergenic Transcription and Developmental Remodeling of Chromatin Subdomains in the Human β-globin Locus | Molecular Cell | 2000 | 323 |
45 | Nucleotide excision repair II: from yeast to mammals | Trends in Genetics | 1993 | 319 |
46 | Absence of Mouse REC8 Cohesin Promotes Synapsis of Sister Chromatids in Meiosis | Developmental Cell | 2005 | 310 |
47 | Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system | Nature Genetics | 2000 | 308 |
48 | Molecular cloning of a human DNA repair gene | Nature | 1984 | 307 |
49 | Defective Transcription-Coupled Repair in Cockayne Syndrome B Mice Is Associated with Skin Cancer Predisposition | Cell | 1997 | 301 |
50 | Crystal Structure of a Human Alkylbase-DNA Repair Enzyme Complexed to DNA | Cell | 1998 | 284 |