| # | Title | Journal | Year | Citations |
|---|
| 1 | Synaptic, transcriptional and chromatin genes disrupted in autism | Nature | 2014 | 2,254 |
| 2 | Functional impact of global rare copy number variation in autism spectrum disorders | Nature | 2010 | 1,803 |
| 3 | Structural Variation of Chromosomes in Autism Spectrum Disorder | American Journal of Human Genetics | 2008 | 1,641 |
| 4 | Mapping autism risk loci using genetic linkage and chromosomal rearrangements | Nature Genetics | 2007 | 1,272 |
| 5 | Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder | Bipolar Disorders | 2018 | 1,079 |
| 6 | Nurturing care: promoting early childhood development | Lancet, The | 2017 | 1,014 |
| 7 | Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders | American Journal of Human Genetics | 2014 | 819 |
| 8 | Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013 | Bipolar Disorders | 2013 | 740 |
| 9 | Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder | Nature Neuroscience | 2017 | 691 |
| 10 | Precursor form of brain‐derived neurotrophic factor and mature brain‐derived neurotrophic factor are decreased in the pre‐clinical stages of Alzheimer's disease | Journal of Neurochemistry | 2005 | 614 |
| 11 | Contribution of SHANK3 Mutations to Autism Spectrum Disorder | American Journal of Human Genetics | 2007 | 604 |
| 12 | The Burden of Schizophrenia on Caregivers | Pharmacoeconomics | 2008 | 592 |
| 13 | Vitamin D deficiency and depression in adults: systematic review and meta-analysis | British Journal of Psychiatry | 2013 | 589 |
| 14 | The role of the hippocampus in the pathophysiology of major depression | Journal of Psychiatry and Neuroscience | 2004 | 529 |
| 15 | A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder | Journal of Psychiatry and Neuroscience | 2009 | 504 |
| 16 | Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation | Nature Genetics | 2010 | 491 |
| 17 | Whole-genome sequencing of quartet families with autism spectrum disorder | Nature Medicine | 2015 | 457 |
| 18 | Detection of Clinically Relevant Genetic Variants in Autism Spectrum Disorder by Whole-Genome Sequencing | American Journal of Human Genetics | 2013 | 429 |
| 19 | Is perfectionism good, bad, or both? Examining models of the perfectionism construct | Personality and Individual Differences | 2004 | 408 |
| 20 | The impact of anxiety disorders on educational achievement | Journal of Anxiety Disorders | 2003 | 390 |
| 21 | Screening for Intimate Partner Violence in Health Care Settings<subtitle>A Randomized Trial</subtitle> | JAMA - Journal of the American Medical Association | 2009 | 356 |
| 22 | Efficacy of family‐based treatment for adolescents with eating disorders: A systematic review and meta‐analysis | International Journal of Eating Disorders | 2013 | 352 |
| 23 | Molecular Diagnostic Yield of Chromosomal Microarray Analysis and Whole-Exome Sequencing in Children With Autism Spectrum Disorder | JAMA - Journal of the American Medical Association | 2015 | 352 |
| 24 | Childhood adversity and personality disorders: Results from a nationally representative population-based study | Journal of Psychiatric Research | 2011 | 305 |
| 25 | SHANK1 Deletions in Males with Autism Spectrum Disorder | American Journal of Human Genetics | 2012 | 292 |
| 26 | Symptom structure in obsessive-compulsive disorder: a confirmatory factor-analytic study | Behaviour Research and Therapy | 1999 | 291 |
| 27 | Obsessive-Compulsive Disorder as a Disturbance of Security Motivation. | Psychological Review | 2004 | 285 |
| 28 | Post‐Traumatic Stress Disorder in Canada | CNS Neuroscience and Therapeutics | 2008 | 274 |
| 29 | Dimensions of perfectionism across the anxiety disorders1An earlier version of this paper was presented in November 1996 at the meeting of the Association for Advancement of Behavior Therapy in New York City.1 | Behaviour Research and Therapy | 1998 | 268 |
| 30 | Epidemiology of Chronic Pain with Psychological Comorbidity: Prevalence, Risk, Course, and Prognosis | Canadian Journal of Psychiatry | 2008 | 252 |
| 31 | Approaches to Screening for Intimate Partner Violence in Health Care Settings | JAMA - Journal of the American Medical Association | 2006 | 251 |
| 32 | Measuring Outcomes in Aesthetic Surgery: A Comprehensive Review of the Literature | Plastic and Reconstructive Surgery | 2003 | 248 |
| 33 | Investigating the structure of the restricted, repetitive behaviours and interests domain of autism | Journal of Child Psychology and Psychiatry and Allied Disciplines | 2006 | 238 |
| 34 | Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer’s disease | Molecular Brain Research | 2003 | 230 |
| 35 | Posterior Hippocampal Volumes Are Associated with Remission Rates in Patients with Major Depressive Disorder | Biological Psychiatry | 2008 | 224 |
| 36 | Manifesto for a European research network into Problematic Usage of the Internet | European Neuropsychopharmacology | 2018 | 216 |
| 37 | Increased proNGF Levels in Subjects with Mild Cognitive Impairment and Mild Alzheimer Disease | Journal of Neuropathology and Experimental Neurology | 2004 | 212 |
| 38 | A randomized controlled trial of cognitive behavioral therapy for individuals at clinical high risk of psychosis | Schizophrenia Research | 2011 | 209 |
| 39 | Comorbidity of internalizing disorders in children with oppositional defiant disorder | European Child and Adolescent Psychiatry | 2007 | 199 |
| 40 | Measurement of victimization in adolescence: Development and validation of the Childhood Experiences of Violence Questionnaire | Child Abuse and Neglect | 2008 | 199 |
| 41 | Predictors of antidepressant response in clinical trials of transcranial magnetic stimulation | International Journal of Neuropsychopharmacology | 2006 | 196 |
| 42 | The Formation of Abnormal Associations in Schizophrenia: Neural and Behavioral Evidence | Neuropsychopharmacology | 2008 | 195 |
| 43 | The exceptional brain of Albert Einstein | Lancet, The | 1999 | 194 |
| 44 | Biomarkers in bipolar disorder: A positional paper from the International Society for Bipolar Disorders Biomarkers Task Force | Australian and New Zealand Journal of Psychiatry | 2013 | 193 |
| 45 | Psychometric properties of the social phobia inventory: Further evaluation | Behaviour Research and Therapy | 2006 | 191 |
| 46 | Catatonia and Its Treatment | Schizophrenia Bulletin | 2010 | 191 |
| 47 | Temperament and its Relationship to Autistic Symptoms in a High-Risk Infant Sib Cohort | Journal of Abnormal Child Psychology | 2009 | 190 |
| 48 | Newer Antiepileptic Drugs in Bipolar Disorder | CNS Drugs | 2002 | 188 |
| 49 | Bilateral Hippocampal Volume Increase in Patients with Bipolar Disorder and Short-term Lithium Treatment | Neuropsychopharmacology | 2008 | 187 |
| 50 | There is an app for that! The current state of mobile applications (apps) for DSM-5 obsessive-compulsive disorder, posttraumatic stress disorder, anxiety and mood disorders | Depression and Anxiety | 2017 | 187 |
