| # | Title | Journal | Year | Citations |
|---|
| 1 | Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome | Gastroenterology | 2004 | 1,246 |
| 2 | ACG Clinical Guideline: Treatment of Helicobacter pylori Infection | American Journal of Gastroenterology | 2017 | 1,084 |
| 3 | The Development and Validation of an Endoscopic Grading System for Barrett’s Esophagus: The Prague C & M Criteria | Gastroenterology | 2006 | 931 |
| 4 | American Gastroenterological Association Institute Guideline on the Diagnosis and Management of Asymptomatic Neoplastic Pancreatic Cysts | Gastroenterology | 2015 | 816 |
| 5 | The Toronto Consensus for the Treatment of Helicobacter pylori Infection in Adults | Gastroenterology | 2016 | 671 |
| 6 | Systematic Review of the Risk of Enteric Infection in Patients Taking Acid Suppression | American Journal of Gastroenterology | 2007 | 538 |
| 7 | Frozen vs Fresh Fecal Microbiota Transplantation and Clinical Resolution of Diarrhea in Patients With RecurrentClostridium difficileInfection | JAMA - Journal of the American Medical Association | 2016 | 511 |
| 8 | American College of Gastroenterology Monograph on the Management of Irritable Bowel Syndrome and Chronic Idiopathic Constipation | American Journal of Gastroenterology | 2014 | 503 |
| 9 | ACG and CAG Clinical Guideline: Management of Dyspepsia | American Journal of Gastroenterology | 2017 | 431 |
| 10 | Visceral hyperalgesia and intestinal dysmotility in a mouse model of postinfective gut dysfunction | Gastroenterology | 2004 | 407 |
| 11 | Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysis | Gut | 2018 | 397 |
| 12 | Systematic review and meta‐analysis: the incidence and prognosis of post‐infectious irritable bowel syndrome | Alimentary Pharmacology and Therapeutics | 2007 | 387 |
| 13 | Is there an optimal degree of acid suppression for healing of duodenal ulcers? | Gastroenterology | 1990 | 346 |
| 14 | Incidence and Epidemiology of Irritable Bowel Syndrome After a Large Waterborne Outbreak of Bacterial Dysentery | Gastroenterology | 2006 | 338 |
| 15 | Effect of Antidepressants and Psychological Therapies, Including Hypnotherapy, in Irritable Bowel Syndrome: Systematic Review and Meta-Analysis | American Journal of Gastroenterology | 2014 | 335 |
| 16 | Capsule Endoscopy Has a Significantly Higher Diagnostic Yield in Patients With Suspected and Established Small-Bowel Crohn's Disease: A Meta-Analysis | American Journal of Gastroenterology | 2010 | 329 |
| 17 | Clinical Practice Guidelines for the Use of Video Capsule Endoscopy | Gastroenterology | 2017 | 306 |
| 18 | A Systematic Review and Meta-Analysis Evaluating the Efficacy of a Gluten-Free Diet and a Low FODMAPS Diet in Treating Symptoms of Irritable Bowel Syndrome | American Journal of Gastroenterology | 2018 | 269 |
| 19 | American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome | American Journal of Gastroenterology | 2018 | 262 |
| 20 | Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk | Gastroenterology | 2000 | 253 |
| 21 | Functional gastrointestinal disorders and mood disorders in patients with inactive inflammatory bowel disease: Prevalence and impact on health | Inflammatory Bowel Diseases | 2006 | 249 |
| 22 | Coeliac disease | Nature Reviews Disease Primers | 2019 | 240 |
| 23 | Intestinal permeability in patients with irritable bowel syndrome after a waterborne outbreak of acute gastroenteritis in Walkerton, Ontario | Alimentary Pharmacology and Therapeutics | 2004 | 237 |
| 24 | Proton Pump Inhibitors and Risk of Fracture: A Systematic Review and Meta-Analysis of Observational Studies | American Journal of Gastroenterology | 2011 | 230 |
| 25 | The role of CD4+ lymphocytes in the susceptibility of mice to stress-induced reactivation of experimental colitis | Nature Medicine | 1999 | 228 |
| 26 | Impaired gastric emptying in mechanically ventilated, critically ill patients | Intensive Care Medicine | 1996 | 227 |
| 27 | Postinfectious Irritable Bowel Syndrome After a Food-Borne Outbreak of Acute Gastroenteritis Attributed to a Viral Pathogen | Clinical Gastroenterology and Hepatology | 2007 | 224 |
| 28 | Management Strategies to Improve Outcomes of Patients With Inflammatory Bowel Diseases | Gastroenterology | 2017 | 220 |
| 29 | EUS: a meta-analysis of test performance in suspected choledocholithiasis | Gastrointestinal Endoscopy | 2008 | 219 |
| 30 | Oncologic Outcomes of Kidney-sparing Surgery Versus Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: A Systematic Review by the EAU Non-muscle Invasive Bladder Cancer Guidelines Panel | European Urology | 2016 | 215 |
| 31 | AGA Clinical Practice Guidelines on the Role of Probiotics in the Management of Gastrointestinal Disorders | Gastroenterology | 2020 | 209 |
| 32 | Canadian Consensus Conference on the Management of Gastroesophageal Reflux Disease in Adults – Update 2004 | Canadian Journal of Gastroenterology & Hepatology | 2005 | 204 |
| 33 | Novel players in coeliac disease pathogenesis: role of the gut microbiota | Nature Reviews Gastroenterology and Hepatology | 2015 | 200 |
| 34 | ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding | American Journal of Gastroenterology | 2021 | 199 |
| 35 | Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline | Canadian Family Physician | 2017 | 199 |
| 36 | Treating Helicobacter pylori infection in primary care patients with uninvestigated dyspepsia: the Canadian adult dyspepsia empiric treatment---Helicobacter pylori positive (CADET-Hp) randomised controlled trial | BMJ: British Medical Journal | 2002 | 193 |
| 37 | Risk of Upper Gastrointestinal Bleeding With Selective Serotonin Reuptake Inhibitors With or Without Concurrent NonSteroidal Anti-Inflammatory Use: A Systematic Review and Meta-Analysis | American Journal of Gastroenterology | 2014 | 176 |
| 38 | Quality of life measurement in gastrointestinal and liver disorders | Gut | 2000 | 175 |
| 39 | Impaired parasympathetic function increases susceptibility to inflammatory bowel disease in a mouse model of depression | Journal of Clinical Investigation | 2008 | 175 |
| 40 | Systematic Review and Meta-analysis | Inflammatory Bowel Diseases | 2017 | 174 |
| 41 | Peptic ulcer disease today | Nature Reviews Gastroenterology & Hepatology | 2006 | 169 |
| 42 | Gastric Cancer as Preventable Disease | Clinical Gastroenterology and Hepatology | 2017 | 162 |
| 43 | Helicobacter pylori infection in functional dyspepsia | Nature Reviews Gastroenterology and Hepatology | 2013 | 157 |
| 44 | Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding | The Cochrane Library | 2010 | 154 |
| 45 | Systematic Review and Meta-Analysis: Infliximab or Cyclosporine as Rescue Therapy in Patients With Severe Ulcerative Colitis Refractory to Steroids | American Journal of Gastroenterology | 2016 | 151 |
| 46 | The Effect of CYP2C19 Polymorphisms on H. pylori Eradication Rate in Dual and Triple First-Line PPI Therapies: A Meta-analysis | American Journal of Gastroenterology | 2006 | 147 |
| 47 | Reactivation of Inflammatory Bowel Disease in a Mouse Model of Depression | Gastroenterology | 2009 | 147 |
| 48 | Meta‐analysis: peri‐operative anti‐TNFα treatment and post‐operative complications in patients with inflammatory bowel disease | Alimentary Pharmacology and Therapeutics | 2013 | 140 |
| 49 | Four-Year Maintenance Treatment With Adalimumab in Patients with Moderately to Severely Active Ulcerative Colitis: Data from ULTRA 1, 2, and 3 | American Journal of Gastroenterology | 2014 | 140 |
| 50 | Interleukin 10 gene transfer prevents experimental colitis in rats | Gut | 2000 | 137 |
