298
Articles
14.7K
Citations
4.2
avg. Impact Factor
66
h-index

Most Cited Articles of Integrative Biology in 2015

TitleJournalYearCitations
Conformation determines the seeding potencies of native and recombinant Tau aggregatesJournal of Biological Chemistry2015168
Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male MiceEndocrinology2015151
LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2Journal of Biological Chemistry201583
Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structuresJournal of Medicinal Chemistry201550
Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor AgonistJournal of Medicinal Chemistry201539
Bias analyses of preclinical and clinical D2 dopamine ligands: studies with immediate and complex signaling pathwaysJournal of Pharmacology and Experimental Therapeutics201530
Hypoxia Affects Neprilysin Expression Through Caspase Activation and an APP Intracellular Domain-dependent MechanismFrontiers in Neuroscience201529
Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin SecretionMolecular Endocrinology201527
Phosphodiesterase 10A inhibitor, MP-10 (PF-2545920), produces greater induction of c-Fos in dopamine D2 neurons than in D1 neurons in the neostriatumNeuropharmacology201523
Molecular targets of androgen signaling that characterize skeletal muscle recovery and regenerationNuclear Receptor Signaling201517
Adipocyte phospholipid transfer protein and lipoprotein metabolismArteriosclerosis, Thrombosis, and Vascular Biology201511
Comparison of predicted extinction coefficients of monoclonal antibodies with experimental values as measured by the Edelhoch methodInternational Journal of Biological Macromolecules201511
Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone AxisMolecular Endocrinology20158
Design and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor β agonistsBioorganic and Medicinal Chemistry Letters20156