Conformation determines the seeding potencies of native and recombinant Tau aggregates | Journal of Biological Chemistry | 2015 | 168 |
Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice | Endocrinology | 2015 | 151 |
LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2 | Journal of Biological Chemistry | 2015 | 83 |
Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structures | Journal of Medicinal Chemistry | 2015 | 50 |
Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist | Journal of Medicinal Chemistry | 2015 | 39 |
Bias analyses of preclinical and clinical D2 dopamine ligands: studies with immediate and complex signaling pathways | Journal of Pharmacology and Experimental Therapeutics | 2015 | 30 |
Hypoxia Affects Neprilysin Expression Through Caspase Activation and an APP Intracellular Domain-dependent Mechanism | Frontiers in Neuroscience | 2015 | 29 |
Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion | Molecular Endocrinology | 2015 | 27 |
Phosphodiesterase 10A inhibitor, MP-10 (PF-2545920), produces greater induction of c-Fos in dopamine D2 neurons than in D1 neurons in the neostriatum | Neuropharmacology | 2015 | 23 |
Molecular targets of androgen signaling that characterize skeletal muscle recovery and regeneration | Nuclear Receptor Signaling | 2015 | 17 |
Adipocyte phospholipid transfer protein and lipoprotein metabolism | Arteriosclerosis, Thrombosis, and Vascular Biology | 2015 | 11 |
Comparison of predicted extinction coefficients of monoclonal antibodies with experimental values as measured by the Edelhoch method | International Journal of Biological Macromolecules | 2015 | 11 |
Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis | Molecular Endocrinology | 2015 | 8 |
Design and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor β agonists | Bioorganic and Medicinal Chemistry Letters | 2015 | 6 |