| NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice | Science | 2016 | 645 |
| Cardiovascular risk and events in 17 low-, middle-, and high-income countries | New England Journal of Medicine | 2014 | 499 |
| BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration | Journal of Neuroscience | 1997 | 445 |
| DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody | Human Molecular Genetics | 1993 | 346 |
| Canadian sedentary behaviour guidelines for children and youth | Applied Physiology, Nutrition and Metabolism | 2011 | 336 |
| Heat stress in older individuals and patients with common chronic diseases | Cmaj | 2010 | 273 |
| Glucoregulatory responses in normal and diabetic dogs recorded by a new tracer method | Metabolism: Clinical and Experimental | 1971 | 269 |
| Morphometry of human coronary capillaries during normal growth and the effect of age in left ventricular pressure-overload hypertrophy | Circulation | 1992 | 253 |
| Satellite cell activity is required for hypertrophy of overloaded adult rat muscle | Muscle and Nerve | 1994 | 241 |
| Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice | Hepatology | 2016 | 223 |
| Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells | Hypertension | 2007 | 218 |
| BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo | European Journal of Neuroscience | 1996 | 218 |
| Mechanical and neuroendocrine regulation of the endocrine heart | Cardiovascular Research | 1996 | 210 |
| Considerations for the measurement of core, skin and mean body temperatures | Journal of Thermal Biology | 2014 | 209 |
| Gamma irradiation prevents compensatory hypertrophy of overloaded mouse extensor digitorum longus muscle | Journal of Applied Physiology | 1992 | 200 |
| Physical work capacity in older adults: implications for the aging worker | American Journal of Industrial Medicine | 2008 | 194 |
| Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts | Developmental Dynamics | 2010 | 185 |
| Response of rubrospinal and corticospinal neurons to injury and neurotrophins | Progress in Brain Research | 1994 | 178 |
| Chronic alterations in dopaminergic neurotransmission produce a persistent elevation of deltaFosB-like protein(s) in both the rodent and primate striatum | European Journal of Neuroscience | 1996 | 169 |
| NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation | Science Translational Medicine | 2016 | 152 |
| Thermometry, calorimetry, and mean body temperature during heat stress | Comprehensive Physiology | 2013 | 151 |
| The effects of extracellular pH and buffer concentration on the efflux of lactate from frog sartorius muscle | Journal of Physiology | 1975 | 148 |
| Direct gene transfer in skeletal muscle: plasmid DNA-based immunization against the hepatitis B virus surface antigen | Vaccine | 1994 | 136 |
| Resistance versus aerobic exercise: acute effects on glycemia in type 1 diabetes | Diabetes Care | 2013 | 133 |
| Thermographic imaging in sports and exercise medicine: A Delphi study and consensus statement on the measurement of human skin temperature | Journal of Thermal Biology | 2017 | 131 |
