| # | Title | Journal | Year | Citations |
|---|
| 1 | CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials | BMJ: British Medical Journal | 2010 | 5,910 |
| 2 | CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials | BMC Medicine | 2010 | 4,939 |
| 3 | SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials | BMJ, The | 2013 | 3,435 |
| 4 | Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? | Lancet, The | 1998 | 3,390 |
| 5 | Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews | BMC Medical Research Methodology | 2007 | 3,253 |
| 6 | CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomized Trials | Annals of Internal Medicine | 2010 | 2,752 |
| 7 | Genome-wide association studies for complex traits: consensus, uncertainty and challenges | Nature Reviews Genetics | 2008 | 2,496 |
| 8 | A systematic review of low back pain cost of illness studies in the United States and internationally | Spine Journal | 2008 | 1,612 |
| 9 | Cleft lip and palate | Lancet, The | 2009 | 1,240 |
| 10 | CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomised Trials | PLoS Medicine | 2010 | 1,135 |
| 11 | Risk Factors for Alzheimer's Disease: A Prospective Analysis from the Canadian Study of Health and Aging | American Journal of Epidemiology | 2002 | 1,041 |
| 12 | Prevalence and severity of cognitive impairment with and without dementia in an elderly population | Lancet, The | 1997 | 893 |
| 13 | Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): Extending the CONSORT Statement | PLoS Medicine | 2010 | 801 |
| 14 | CONSORT 2010 Statement: Updated guidelines for reporting parallel group randomised trials | Journal of Clinical Epidemiology | 2010 | 769 |
| 15 | Human Health Risk Assessment for Aluminium, Aluminium Oxide, and Aluminium Hydroxide | Journal of Toxicology and Environmental Health - Part B: Critical Reviews | 2007 | 741 |
| 16 | CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials | Journal of Pharmacology and Pharmacotherapeutics | 2010 | 695 |
| 17 | Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study | Lancet, The | 2008 | 693 |
| 18 | Ambient air pollution, birth weight and preterm birth: A systematic review and meta-analysis | Environmental Research | 2012 | 638 |
| 19 | The CARE Guidelines: Consensus‐Based Clinical Case Reporting Guideline Development | Headache | 2013 | 628 |
| 20 | Developing Core Outcome Measurement Sets for Clinical Trials: OMERACT Filter 2.0 | Journal of Clinical Epidemiology | 2014 | 625 |
| 21 | Validation of the 28-joint Disease Activity Score (DAS28) and European League Against Rheumatism response criteria based on C-reactive protein against disease progression in patients with rheumatoid arthritis, and comparison with the DAS28 based on erythrocyte sedimentation rate | Annals of the Rheumatic Diseases | 2009 | 604 |
| 22 | The CARE Guidelines: Consensus-based Clinical Case Reporting Guideline Development | Global Advances in Health and Medicine | 2013 | 575 |
| 23 | A study to develop clinical decision rules for the use of radiography in acute ankle injuries | Annals of Emergency Medicine | 1992 | 567 |
| 24 | Assessment of cumulative evidence on genetic associations: interim guidelines | International Journal of Epidemiology | 2008 | 506 |
| 25 | Adverse effects of biologics: a network meta-analysis and Cochrane overview | The Cochrane Library | 2016 | 481 |
| 26 | Long-term Ambient Fine Particulate Matter Air Pollution and Lung Cancer in a Large Cohort of Never-Smokers | American Journal of Respiratory and Critical Care Medicine | 2011 | 439 |
| 27 | Viscosupplementation for the treatment of osteoarthritis of the knee | The Cochrane Library | 2006 | 418 |
| 28 | COVID-19 transmission in Mainland China is associated with temperature and humidity: A time-series analysis | Science of the Total Environment | 2020 | 418 |
| 29 | STrengthening the REporting of Genetic Association Studies (STREGA)— An Extension of the STROBE Statement | PLoS Medicine | 2009 | 411 |
| 30 | Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip | Nature Genetics | 2008 | 382 |
| 31 | Toward The ‘Tipping Point’: Decision Aids And Informed Patient Choice | Health Affairs | 2007 | 374 |
| 32 | A Combined Analysis of North American Case-Control Studies of Residential Radon and Lung Cancer | Journal of Toxicology and Environmental Health - Part A: Current Issues | 2006 | 354 |
| 33 | CONSORT 2010 Statement | Obstetrics and Gynecology | 2010 | 338 |
| 34 | Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): Extending the CONSORT Statement | Journal of Evidence-Based Medicine | 2010 | 335 |
| 35 | Obesity May Increase the Incidence of Asthma in Women but Not in Men: Longitudinal Observations from the Canadian National Population Health Surveys | American Journal of Epidemiology | 2002 | 327 |
| 36 | Temporal Variation in Heat–Mortality Associations: A Multicountry Study | Environmental Health Perspectives | 2015 | 326 |
| 37 | Implementation of evidence-based treatment protocols to manage fever, hyperglycaemia, and swallowing dysfunction in acute stroke (QASC): a cluster randomised controlled trial | Lancet, The | 2011 | 323 |
| 38 | Early determinants of overweight at 4.5 years in a population-based longitudinal study | International Journal of Obesity | 2006 | 305 |
| 39 | A systematic review of perceived risks, psychological and behavioral impacts of genetic testing | Genetics in Medicine | 2008 | 292 |
| 40 | Reporting Guidelines for Survey Research: An Analysis of Published Guidance and Reporting Practices | PLoS Medicine | 2011 | 284 |
| 41 | Spatial Analysis of Air Pollution and Mortality in California | American Journal of Respiratory and Critical Care Medicine | 2013 | 284 |
| 42 | Community screening for dementia: The Mini Mental State Exam (MMSE) and modified Mini-Mental State Exam (3MS) compared | Journal of Clinical Epidemiology | 1997 | 270 |
| 43 | Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women | The Cochrane Library | 2008 | 260 |
| 44 | Increased Effects of Smoking and Obesity on Asthma among Female Canadians: The National Population Health Survey, 1994-1995 | American Journal of Epidemiology | 1999 | 254 |
| 45 | Association between gaseous ambient air pollutants and adverse pregnancy outcomes in Vancouver, Canada. | Environmental Health Perspectives | 2003 | 253 |
| 46 | Measures of self-perceived well-being | Journal of Psychosomatic Research | 2010 | 252 |
| 47 | The Epidemiology of Chronic Rhinosinusitis in Canadians | Laryngoscope | 2003 | 251 |
| 48 | Prospective Validation of the San Francisco Syncope Rule to Predict Patients With Serious Outcomes | Annals of Emergency Medicine | 2006 | 250 |
| 49 | A road map for efficient and reliable human genome epidemiology | Nature Genetics | 2006 | 244 |
| 50 | A New Multipollutant, No-Threshold Air Quality Health Index Based on Short-Term Associations Observed in Daily Time-Series Analyses | Journal of the Air and Waste Management Association | 2008 | 238 |
