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Ottawa Institute of Systems Biology
›
Top Articles
Ottawa Institute of Systems Biology
96
(top 1%)
papers
2.9K
(top 1%)
citations
29
(top 1%)
h
-index
52
(top 1%)
g
-index
112
all documents
3.2K
doc citations
983
citing journals
81
times ranked
Top Articles
#
Title
Journal
Year
Citations
1
Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease
Nature Communications
2016
326
2
The Tale of Two Domains
Molecular and Cellular Proteomics
2008
168
3
Adaptation to Stressors by Systemic Protein Amyloidogenesis
Developmental Cell
2016
136
4
Extreme Genomic CpG Deficiency in SARS-CoV-2 and Evasion of Host Antiviral Defense
Molecular Biology and Evolution
2020
136
5
A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy
Nature Communications
2018
126
6
Functional Impacts of the Intestinal Microbiome in the Pathogenesis of Inflammatory Bowel Disease
Inflammatory Bowel Diseases
2015
112
7
Proteomics: from Gel Based to Gel Free
Analytical Chemistry
2005
104
8
Functional Dissection of the NuA4 Histone Acetyltransferase Reveals Its Role as a Genetic Hub and that Eaf1 Is Essential for Complex Integrity
Molecular and Cellular Biology
2008
101
9
Novel Loss-of-Function PCSK9 Variant Is Associated with Low Plasma LDL Cholesterol in a French-Canadian Family and with Impaired Processing and Secretion in Cell Culture
Clinical Chemistry
2011
101
10
Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone
Nature Biomedical Engineering
2020
97
11
Two-Color Cell Array Screen Reveals Interdependent Roles for Histone Chaperones and a Chromatin Boundary Regulator in Histone Gene Repression
Molecular Cell
2009
88
12
A Non-Death Role of the Yeast Metacaspase: Yca1p Alters Cell Cycle Dynamics
PLoS ONE
2008
83
13
Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry
Proteomics
2007
76
14
Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signaling
Nucleic Acids Research
2014
70
15
Gene Expression Noise Facilitates Adaptation and Drug Resistance Independently of Mutation
Physical Review Letters
2011
66
16
Exploring the Yeast Acetylome Using Functional Genomics
Cell
2012
63
17
Improvement of the reverse tetracycline transactivator by single amino acid substitutions that reduce leaky target gene expression to undetectable levels
Scientific Reports
2016
54
18
Strong Eukaryotic IRESs Have Weak Secondary Structure
PLoS ONE
2009
54
19
Resistant starch, microbiome, and precision modulation
Gut Microbes
2021
53
20
Regulation of Autophagy Enzymes by Nutrient Signaling
Trends in Biochemical Sciences
2021
48
21
Glycemic variability is associated with subclinical atherosclerosis in Chinese type 2 diabetic patients
Cardiovascular Diabetology
2013
44
22
A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts
Skeletal Muscle
2012
43
23
Proteomics: From Technology Developments to Biological Applications
Analytical Chemistry
2009
42
24
Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing
Nature Communications
2015
42
25
SOX15 and SOX7 Differentially Regulate the Myogenic Program in P19 Cells
Stem Cells
2009
41
26
Targeted lipidomics – advances in profiling lysophosphocholine and platelet‐activating factor second messengers
FEBS Journal
2013
38
27
Model-based rational design of an oncolytic virus with improved therapeutic potential
Nature Communications
2013
38
28
Proteomics characterization of mitochondrial‐derived vesicles under oxidative stress
FASEB Journal
2021
36
29
Six1 Regulates MyoD Expression in Adult Muscle Progenitor Cells
PLoS ONE
2013
35
30
Estimating the Stochastic Bifurcation Structure of Cellular Networks
PLoS Computational Biology
2010
32
31
Genome‐wide association between Six4, MyoD, and the histone demethylase Utx during myogenesis
FASEB Journal
2015
32
32
Improved Recovery and Identification of Membrane Proteins from Rat Hepatic Cells using a Centrifugal Proteomic Reactor
Molecular and Cellular Proteomics
2011
31
33
The cost of wobble translation in fungal mitochondrial genomes: integration of two traditional hypotheses
BMC Evolutionary Biology
2008
29
34
Methylmercury can induce Parkinson’s-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells
Journal of Toxicological Sciences
2015
28
35
Chromosomal Position Effects Are Linked to Sir2-Mediated Variation in Transcriptional Burst Size
Biophysical Journal
2011
27
36
Uncovering the Proteome Response of the Master Circadian Clock to Light Using an AutoProteome System
Molecular and Cellular Proteomics
2011
26
37
High throughput solid phase microextraction: A new alternative for analysis of cellular lipidome?
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
2017
26
38
Cancer Stem Cell-Associated Pathways in the Metabolic Reprogramming of Breast Cancer
International Journal of Molecular Sciences
2020
26
39
Phenotypic impact of regulatory noise in cellular stress-response pathways
Systems and Synthetic Biology
2010
25
40
Budding yeast Wee1 distinguishes spindle pole bodies to guide their pattern of age-dependent segregation
Nature Cell Biology
2017
24
41
Re-evaluating the role of epithelial-mesenchymal-transition in cancer progression
Journal of Biomedical Research
2018
22
42
Phosphoproteome analysis of an early onset mouse model (
T
g
CRND
8) of
A
lzheimer's disease reveals temporal changes in neuronal and glia signaling pathways
Proteomics
2013
17
43
MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation
Stem Cell Reports
2015
17
44
Quantitative Proteomic Analysis of PCSK9 Gain of Function in Human Hepatic HuH7 Cells
Journal of Proteome Research
2011
15
45
Quantitative Epistasis Analysis and Pathway Inference from Genetic Interaction Data
PLoS Computational Biology
2011
15
46
Regulation of Hspb7 by MEF2 and AP-1: implications for Hspb7 in muscle atrophy
Journal of Cell Science
2016
15
47
Cdk1 phosphorylation of Esp1/Separase functions with PP2A and Slk19 to regulate pericentric Cohesin and anaphase onset
PLoS Genetics
2018
15
48
Snf2h Drives Chromatin Remodeling to Prime Upper Layer Cortical Neuron Development
Frontiers in Molecular Neuroscience
2019
15
49
Combination of online enzyme digestion with stable isotope labeling for high‐throughput quantitative proteome analysis
Proteomics
2012
14
50
Proteomic Analysis of Cerebellum in Common Marmoset Exposed to Methylmercury
Toxicological Sciences
2015
14
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