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Top Articles

#TitleJournalYearCitations
1Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s diseaseNature Communications2016326
2The Tale of Two DomainsMolecular and Cellular Proteomics2008168
3Adaptation to Stressors by Systemic Protein AmyloidogenesisDevelopmental Cell2016136
4Extreme Genomic CpG Deficiency in SARS-CoV-2 and Evasion of Host Antiviral DefenseMolecular Biology and Evolution2020136
5A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagyNature Communications2018126
6Functional Impacts of the Intestinal Microbiome in the Pathogenesis of Inflammatory Bowel DiseaseInflammatory Bowel Diseases2015112
7Proteomics:  from Gel Based to Gel FreeAnalytical Chemistry2005104
8Functional Dissection of the NuA4 Histone Acetyltransferase Reveals Its Role as a Genetic Hub and that Eaf1 Is Essential for Complex IntegrityMolecular and Cellular Biology2008101
9Novel Loss-of-Function PCSK9 Variant Is Associated with Low Plasma LDL Cholesterol in a French-Canadian Family and with Impaired Processing and Secretion in Cell CultureClinical Chemistry2011101
10Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backboneNature Biomedical Engineering202097
11Two-Color Cell Array Screen Reveals Interdependent Roles for Histone Chaperones and a Chromatin Boundary Regulator in Histone Gene RepressionMolecular Cell200988
12A Non-Death Role of the Yeast Metacaspase: Yca1p Alters Cell Cycle DynamicsPLoS ONE200883
13Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometryProteomics200776
14Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signalingNucleic Acids Research201470
15Gene Expression Noise Facilitates Adaptation and Drug Resistance Independently of MutationPhysical Review Letters201166
16Exploring the Yeast Acetylome Using Functional GenomicsCell201263
17Improvement of the reverse tetracycline transactivator by single amino acid substitutions that reduce leaky target gene expression to undetectable levelsScientific Reports201654
18Strong Eukaryotic IRESs Have Weak Secondary StructurePLoS ONE200954
19Resistant starch, microbiome, and precision modulationGut Microbes202153
20Regulation of Autophagy Enzymes by Nutrient SignalingTrends in Biochemical Sciences202148
21Glycemic variability is associated with subclinical atherosclerosis in Chinese type 2 diabetic patientsCardiovascular Diabetology201344
22A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblastsSkeletal Muscle201243
23Proteomics: From Technology Developments to Biological ApplicationsAnalytical Chemistry200942
24Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killingNature Communications201542
25SOX15 and SOX7 Differentially Regulate the Myogenic Program in P19 CellsStem Cells200941
26Targeted lipidomics – advances in profiling lysophosphocholine and platelet‐activating factor second messengersFEBS Journal201338
27Model-based rational design of an oncolytic virus with improved therapeutic potentialNature Communications201338
28Proteomics characterization of mitochondrial‐derived vesicles under oxidative stressFASEB Journal202136
29Six1 Regulates MyoD Expression in Adult Muscle Progenitor CellsPLoS ONE201335
30Estimating the Stochastic Bifurcation Structure of Cellular NetworksPLoS Computational Biology201032
31Genome‐wide association between Six4, MyoD, and the histone demethylase Utx during myogenesisFASEB Journal201532
32Improved Recovery and Identification of Membrane Proteins from Rat Hepatic Cells using a Centrifugal Proteomic ReactorMolecular and Cellular Proteomics201131
33The cost of wobble translation in fungal mitochondrial genomes: integration of two traditional hypothesesBMC Evolutionary Biology200829
34Methylmercury can induce Parkinson’s-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cellsJournal of Toxicological Sciences201528
35Chromosomal Position Effects Are Linked to Sir2-Mediated Variation in Transcriptional Burst SizeBiophysical Journal201127
36Uncovering the Proteome Response of the Master Circadian Clock to Light Using an AutoProteome SystemMolecular and Cellular Proteomics201126
37High throughput solid phase microextraction: A new alternative for analysis of cellular lipidome?Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences201726
38Cancer Stem Cell-Associated Pathways in the Metabolic Reprogramming of Breast CancerInternational Journal of Molecular Sciences202026
39Phenotypic impact of regulatory noise in cellular stress-response pathwaysSystems and Synthetic Biology201025
40Budding yeast Wee1 distinguishes spindle pole bodies to guide their pattern of age-dependent segregationNature Cell Biology201724
41Re-evaluating the role of epithelial-mesenchymal-transition in cancer progressionJournal of Biomedical Research201822
42Phosphoproteome analysis of an early onset mouse model (TgCRND8) of Alzheimer's disease reveals temporal changes in neuronal and glia signaling pathwaysProteomics201317
43MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell ImmunomodulationStem Cell Reports201517
44Quantitative Proteomic Analysis of PCSK9 Gain of Function in Human Hepatic HuH7 CellsJournal of Proteome Research201115
45Quantitative Epistasis Analysis and Pathway Inference from Genetic Interaction DataPLoS Computational Biology201115
46Regulation of Hspb7 by MEF2 and AP-1: implications for Hspb7 in muscle atrophyJournal of Cell Science201615
47Cdk1 phosphorylation of Esp1/Separase functions with PP2A and Slk19 to regulate pericentric Cohesin and anaphase onsetPLoS Genetics201815
48Snf2h Drives Chromatin Remodeling to Prime Upper Layer Cortical Neuron DevelopmentFrontiers in Molecular Neuroscience201915
49Combination of online enzyme digestion with stable isotope labeling for high‐throughput quantitative proteome analysisProteomics201214
50Proteomic Analysis of Cerebellum in Common Marmoset Exposed to MethylmercuryToxicological Sciences201514