| # | Title | Journal | Year | Citations |
|---|
| 1 | Host-generated double stranded RNA induces RNAi in plant-parasitic nematodes and protects the host from infection | Molecular and Biochemical Parasitology | 2006 | 231 |
| 2 | Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor | Nature | 2020 | 177 |
| 3 | Methodological advances: the unsung heroes of the GPCR structural revolution | Nature Reviews Molecular Cell Biology | 2015 | 175 |
| 4 | Lafora progressive myoclonus epilepsy: A meta-analysis of reported mutations in the first decade following the discovery of theEPM2AandNHLRC1genes | Human Mutation | 2009 | 171 |
| 5 | Electrospraying: A facile technique for synthesis of chitosan‐based micro/nanospheres for drug delivery applications | Journal of Biomedical Materials Research - Part B Applied Biomaterials | 2009 | 150 |
| 6 | Functional competence of a partially engaged GPCR–β-arrestin complex | Nature Communications | 2016 | 144 |
| 7 | Recent advances in the molecular basis of Lafora’s progressive myoclonus epilepsy | Journal of Human Genetics | 2006 | 130 |
| 8 | Emerging Functional Divergence of β-Arrestin Isoforms in GPCR Function | Trends in Endocrinology and Metabolism | 2015 | 124 |
| 9 | Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation | Development (Cambridge) | 2015 | 115 |
| 10 | PknB-Mediated Phosphorylation of a Novel Substrate, N-Acetylglucosamine-1-Phosphate Uridyltransferase, Modulates Its Acetyltransferase Activity | Journal of Molecular Biology | 2009 | 112 |
| 11 | The malin–laforin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin–proteasome system | Human Molecular Genetics | 2009 | 106 |
| 12 | Emerging structural insights into biased GPCR signaling | Trends in Biochemical Sciences | 2014 | 97 |
| 13 | Homology modeling of major intrinsic proteins in rice, maize and Arabidopsis: comparative analysis of transmembrane helix association and aromatic/arginine selectivity filters | BMC Structural Biology | 2007 | 94 |
| 14 | Therapeutic implication of L-phenylalanine aggregation mechanism and its modulation by D-phenylalanine in phenylketonuria | Scientific Reports | 2014 | 92 |
| 15 | Novel Structural Insights into GPCR–β-Arrestin Interaction and Signaling | Trends in Cell Biology | 2017 | 90 |
| 16 | Core engagement with β-arrestin is dispensable for agonist-induced vasopressin receptor endocytosis and ERK activation | Molecular Biology of the Cell | 2017 | 87 |
| 17 | Molecular mechanism of modulating arrestin conformation by GPCR phosphorylation | Nature Structural and Molecular Biology | 2018 | 87 |
| 18 | BMP signaling in development and diseases: A pharmacological perspective | Biochemical Pharmacology | 2013 | 86 |
| 19 | Dysfunctions in endosomal–lysosomal and autophagy pathways underlie neuropathology in a mouse model for Lafora disease | Human Molecular Genetics | 2012 | 85 |
| 20 | Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment | Human Molecular Genetics | 2007 | 84 |
| 21 | Community guidelines for GPCR ligand bias: IUPHAR review 32 | British Journal of Pharmacology | 2022 | 84 |
| 22 | Inflammatory system gene polymorphism and the risk of stroke: A case–control study in an Indian population | Brain Research Bulletin | 2008 | 82 |
| 23 | Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: a meta-analysis | Journal of Human Genetics | 2007 | 77 |
| 24 | C. elegans RNA-binding proteins PUF-8 and MEX-3 function redundantly to promote germline stem cell mitosis | Developmental Biology | 2009 | 75 |
| 25 | The carbohydrate-binding domain of Lafora disease protein targets Lafora polyglucosan bodies | Biochemical and Biophysical Research Communications | 2004 | 72 |
| 26 | The SCN1A gene variants and epileptic encephalopathies | Journal of Human Genetics | 2013 | 72 |
| 27 | Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors | Molecular Cell | 2021 | 69 |
| 28 | Emerging Approaches to GPCR Ligand Screening for Drug Discovery | Trends in Molecular Medicine | 2015 | 68 |
| 29 | Multiple maternal proteins coordinate to restrict the translation ofC. elegans nanos-2to primordial germ cells | Development (Cambridge) | 2008 | 66 |
| 30 | ATCUN-like metal-binding motifs in proteins: Identification and characterization by crystal structure and sequence analysis | Proteins: Structure, Function and Bioinformatics | 2004 | 62 |
| 31 | Targeting NF-kappa B Signaling by Artesunate Restores Sensitivity of Castrate-Resistant Prostate Cancer Cells to Antiandrogens | Neoplasia | 2017 | 62 |
| 32 | Reserpine ameliorates Aβ toxicity in the Alzheimer’s disease model in Caenorhabditis elegans | Experimental Gerontology | 2009 | 58 |
| 33 | Biased ligands at opioid receptors: Current status and future directions | Science Signaling | 2021 | 58 |
| 34 | Emerging Insights into the Structure and Function of Complement C5a Receptors | Trends in Biochemical Sciences | 2020 | 57 |
| 35 | Post‐prandial reflux suppression by a raft‐forming alginate (Gaviscon Advance) compared to a simple antacid documented by magnetic resonance imaging and pH‐impedance monitoring: mechanistic assessment in healthy volunteers and randomised, controlled, double‐blind study in reflux patients | Alimentary Pharmacology and Therapeutics | 2013 | 56 |
| 36 | Distinct phosphorylation sites in a prototypical GPCR differently orchestrate β-arrestin interaction, trafficking, and signaling | Science Advances | 2020 | 55 |
| 37 | Decreased O-Linked GlcNAcylation Protects from Cytotoxicity Mediated by Huntingtin Exon1 Protein Fragment | Journal of Biological Chemistry | 2014 | 54 |
| 38 | Abnormal Structure and Function of the Esophagogastric Junction and Proximal Stomach in Gastroesophageal Reflux Disease | American Journal of Gastroenterology | 2014 | 54 |
| 39 | Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms | Cell Reports | 2019 | 54 |
| 40 | Key Residues in Mycobacterium tuberculosis Protein Kinase G Play a Role in Regulating Kinase Activity and Survival in the Host | Journal of Biological Chemistry | 2009 | 53 |
| 41 | Human satellite-III non-coding RNAs modulate heat shock-induced transcriptional repression | Journal of Cell Science | 2016 | 53 |
| 42 | Post‐translational modifications in capsid proteins of recombinant adeno‐associated virus (AAV) 1‐rh10 serotypes | FEBS Journal | 2019 | 53 |
| 43 | Hyperphosphorylation and Aggregation of Tau in Laforin-deficient Mice, an Animal Model for Lafora Disease | Journal of Biological Chemistry | 2009 | 52 |
| 44 | Cerebrospinal Fluid from sporadic Amyotrophic Lateral Sclerosis patients induces degeneration of a cultured motor neuron cell line | Brain Research | 2009 | 52 |
| 45 | Structural stabilization of GTP-binding domains in circularly permuted GTPases: Implications for RNA binding | Nucleic Acids Research | 2006 | 51 |
| 46 | Fat and Wingless signaling oppositely regulate epithelial cell-cell adhesion and distal wing development in Drosophila | Development (Cambridge) | 2006 | 51 |
| 47 | Reserpine can confer stress tolerance and lifespan extension in the nematode C. elegans | Biogerontology | 2008 | 51 |
| 48 | SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression | Oncogenesis | 2015 | 50 |
| 49 | Illuminating GPCR Signaling by Cryo-EM | Trends in Cell Biology | 2018 | 49 |
| 50 | Novel NHLRC1 mutations and genotype-phenotype correlations in patients with Lafora's progressive myoclonic epilepsy | Journal of Medical Genetics | 2006 | 48 |
