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exaly
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Department of Biochemistry
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top-articles
Department of Biochemistry
437
(top 1%)
papers
30.2K
(top 1%)
citations
86
(top 0.1%)
h
-index
163
(top 0.1%)
g
-index
539
all documents
32.1K
doc citations
3.6K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
The ubiquitin pathway in Parkinson's disease
Nature
1998
1,518
2
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
Nature
2007
1,369
3
The therapeutic potential of monoamine oxidase inhibitors
Nature Reviews Neuroscience
2006
1,163
4
Classical Nuclear Localization Signals: Definition, Function, and Interaction with Importin α*
Journal of Biological Chemistry
2007
966
5
5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging
Nature Neuroscience
2011
746
6
[11] Redox potential of GSH/GSSG couple: Assay and biological significance
Methods in Enzymology
2002
673
7
Mitochondrial control of apoptosis: the role of cytochrome c
Biochimica Et Biophysica Acta - Bioenergetics
1998
637
8
BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression
Oncogene
1998
636
9
Cisplatin Induces a Mitochondrial-ROS Response That Contributes to Cytotoxicity Depending on Mitochondrial Redox Status and Bioenergetic Functions
PLoS ONE
2013
575
10
Regulation of ubiquitin‐dependent processes by deubiquitinating enzymes
FASEB Journal
1997
548
11
Overlap extension PCR cloning: a simple and reliable way to create recombinant plasmids
BioTechniques
2010
482
12
Glutathione in Human Plasma: Decline in Association with Aging, Age-Related Macular Degeneration, and Diabetes
Free Radical Biology and Medicine
1998
434
13
Substrate Specificity of Deubiquitinating Enzymes: Ubiquitin C-Terminal Hydrolases†
Biochemistry
1998
381
14
Mechanism of assembly of the tyrosyl radical-dinuclear iron cluster cofactor of ribonucleotide reductase
Science
1991
363
15
Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa
Nature Genetics
2003
351
16
Redox analysis of human plasma allows separation of pro-oxidant events of aging from decline in antioxidant defenses
Free Radical Biology and Medicine
2002
349
17
Quantitation of free sphingosine in liver by high-performance liquid chromatography
Analytical Biochemistry
1988
324
18
Compartmentation of Glutathione: Implications for the Study of Toxicity and Disease
Toxicology and Applied Pharmacology
1996
314
19
Protein lysine methyltransferase G9a acts on non-histone targets
Nature Chemical Biology
2008
309
20
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells
Nature Genetics
1999
302
21
Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen
Nature
2012
283
22
Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294
Nature Structural and Molecular Biology
2009
272
23
Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease
Molecular Neurodegeneration
2018
267
24
Characterization of Ceramide Synthesis
Journal of Biological Chemistry
1997
266
25
Redox Potential of Human Thioredoxin 1 and Identification of a Second Dithiol/Disulfide Motif
Journal of Biological Chemistry
2003
264
26
Molecular and Mechanistic Properties of the Membrane-Bound Mitochondrial Monoamine Oxidases
Biochemistry
2009
258
27
The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules
Nature Structural and Molecular Biology
2008
250
28
Structure of the Neurospora SET Domain Protein DIM-5, a Histone H3 Lysine Methyltransferase
Cell
2002
247
29
Evolutionary history and metabolic insights of ancient mammalian uricases
Proceedings of the National Academy of Sciences of the United States of America
2014
238
30
Differential Roles of Galectin-1 and Galectin-3 in Regulating Leukocyte Viability and Cytokine Secretion
Journal of Immunology
2008
232
31
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling
Nature Immunology
2011
230
32
Inhibition of the 26 S Proteasome by Polyubiquitin Chains Synthesized to Have Defined Lengths
Journal of Biological Chemistry
1997
207
33
Cancer vaccines and carbohydrate epitopes
Vaccine
2011
203
34
Apoptosis: Cell death defined by caspase activation
Cell Death and Differentiation
1999
195
35
Substrate Binding and Catalysis by Ubiquitin C-Terminal Hydrolases: Identification of Two Active Site Residues†
Biochemistry
1996
194
36
Glutathione and thioredoxin redox during differentiation in human colon epithelial (Caco-2) cells
American Journal of Physiology - Renal Physiology
2002
194
37
Demonstration of Isoleucine 199 as a Structural Determinant for the Selective Inhibition of Human Monoamine Oxidase B by Specific Reversible Inhibitors
Journal of Biological Chemistry
2005
189
38
Specific and Covalent Targeting of Conjugating and Deconjugating Enzymes of Ubiquitin-Like Proteins
Molecular and Cellular Biology
2004
184
39
Glutathione dependent control of protein disulfide-sulfhydryl content by subcellular fractions of hepatic tissue
Biochimica Et Biophysica Acta - General Subjects
1977
178
40
Shotgun glycomics: a microarray strategy for functional glycomics
Nature Methods
2011
176
41
Colonic Cell Proliferation and Aberrant Crypt Foci Formation Are Inhibited by Dairy Glycosphingolipids in 1,2-Dimethylhydrazine-Treated CF1 Mice
Journal of Nutrition
2000
173
42
Mitogen-activated Protein (MAP) Kinase Is Regulated by the MAP Kinase Phosphatase (MKP-1) in Vascular Smooth Muscle Cells
Journal of Biological Chemistry
1995
168
43
The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds
Nature Structural Biology
2002
168
44
Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet–fed mice
Science Translational Medicine
2016
160
45
Structural Basis for Benzothiazinone-Mediated Killing of
Mycobacterium tuberculosis
Science Translational Medicine
2012
159
46
A Mitochondrial DNA Mutation as a Cause of Leber's Hereditary Optic Neuropathy
New England Journal of Medicine
1989
158
47
DEN1 Is a Dual Function Protease Capable of Processing the C Terminus of Nedd8 and Deconjugating Hyper-neddylated CUL1
Journal of Biological Chemistry
2003
154
48
Multicopy Suppression Underpins Metabolic Evolvability
Molecular Biology and Evolution
2007
154
49
Glutathione in foods listed in the national cancer institute's health habits and history food frequency questionnaire
Nutrition and Cancer
1992
153
50
Regulation of proteolysis by human deubiquitinating enzymes
Biochimica Et Biophysica Acta - Molecular Cell Research
2014
149
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