| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | A Draft Sequence of the Neandertal Genome | Science | 2010 | 3,588 |
| 3 | The complete genome sequence of a Neanderthal from the Altai Mountains | Nature | 2014 | 1,830 |
| 4 | Lineage relationship and protective immunity of memory CD8 T cell subsets | Nature Immunology | 2003 | 1,621 |
| 5 | Genetic history of an archaic hominin group from Denisova Cave in Siberia | Nature | 2010 | 1,537 |
| 6 | CTCF: Master Weaver of the Genome | Cell | 2009 | 1,371 |
| 7 | Humoral Immunity Due to Long-Lived Plasma Cells | Immunity | 1998 | 1,105 |
| 8 | Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment | Cell | 2013 | 1,050 |
| 9 | CTCF: an architectural protein bridging genome topology and function | Nature Reviews Genetics | 2014 | 892 |
| 10 | Genome sequence of a 45,000-year-old modern human from western Siberia | Nature | 2014 | 856 |
| 11 | Organizational principles of 3D genome architecture | Nature Reviews Genetics | 2018 | 832 |
| 12 | Enhancer function: new insights into the regulation of tissue-specific gene expression | Nature Reviews Genetics | 2011 | 768 |
| 13 | Definitions and guidelines for research on antibiotic persistence | Nature Reviews Microbiology | 2019 | 748 |
| 14 | The biological cost of antibiotic resistance | Current Opinion in Microbiology | 1999 | 747 |
| 15 | Biological and biomedical implications of the co-evolution of pathogens and their hosts | Nature Genetics | 2002 | 729 |
| 16 | Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse | Nature | 2013 | 717 |
| 17 | Abnormal Spine Morphology and Enhanced LTP in LIMK-1 Knockout Mice | Neuron | 2002 | 609 |
| 18 | Emerging pathogens: the epidemiology and evolution of species jumps | Trends in Ecology and Evolution | 2005 | 597 |
| 19 | DNA MISMATCH REPAIR AND GENETIC INSTABILITY | Annual Review of Genetics | 2000 | 561 |
| 20 | A Revised Timescale for Human Evolution Based on Ancient Mitochondrial Genomes | Current Biology | 2013 | 540 |
| 21 | A Ribosomal RNA Gene Probe Differentiates Member Species of the Anopheles gambiae Complex | American Journal of Tropical Medicine and Hygiene | 1987 | 508 |
| 22 | Compensatory Mutations, Antibiotic Resistance and the Population Genetics of Adaptive Evolution in Bacteria | Genetics | 2000 | 498 |
| 23 | The role of evolution in the emergence of infectious diseases | Nature | 2003 | 473 |
| 24 | Gene Density, Transcription, and Insulators Contribute to the Partition of the Drosophila Genome into Physical Domains | Molecular Cell | 2012 | 461 |
| 25 | Evolutionarily Conserved Principles Predict 3D Chromatin Organization | Molecular Cell | 2017 | 458 |
| 26 | Non-inherited antibiotic resistance | Nature Reviews Microbiology | 2006 | 447 |
| 27 | Assuring the quality of next-generation sequencing in clinical laboratory practice | Nature Biotechnology | 2012 | 437 |
| 28 | Population and evolutionary dynamics of phage therapy | Nature Reviews Microbiology | 2004 | 434 |
| 29 | Dynamic evolution of the innate immune system in Drosophila | Nature Genetics | 2007 | 400 |
| 30 | Animal Behavior and the Microbiome | Science | 2012 | 400 |
| 31 | Modeling Single-Neuron Dynamics and Computations: A Balance of Detail and Abstraction | Science | 2006 | 396 |
| 32 | Effector CD8 T cells dedifferentiate into long-lived memory cells | Nature | 2017 | 378 |
| 33 | Adaptation to the fitness costs of antibiotic resistance inEscherichia coli | Proceedings of the Royal Society B: Biological Sciences | 1997 | 368 |
| 34 | Emerging human infectious diseases and the links to global food production | Nature Sustainability | 2019 | 362 |
| 35 | The epidemiology of antibiotic resistance in hospitals: Paradoxes and prescriptions | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 359 |
| 36 | RNA-Mediated Neurodegeneration Caused by the Fragile X Premutation rCGG Repeats in Drosophila | Neuron | 2003 | 344 |
| 37 | Neuronal control of leech behavior | Progress in Neurobiology | 2005 | 336 |
| 38 | Natural Selection, Infectious Transfer and the Existence Conditions for Bacterial Plasmids | Genetics | 2000 | 332 |
| 39 | Why infectious disease research needs community ecology | Science | 2015 | 330 |
| 40 | Membrane potential synchrony of simultaneously recorded striatal spiny neurons in vivo | Nature | 1998 | 322 |
| 41 | Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells | Cell Reports Medicine | 2021 | 316 |
| 42 | Immunological characteristics govern the transition of COVID-19 to endemicity | Science | 2021 | 315 |
| 43 | Hairy Root Transformation Using Agrobacterium rhizogenes as a Tool for Exploring Cell Type-Specific Gene Expression and Function Using Tomato as a Model | Plant Physiology | 2014 | 309 |
| 44 | The Drosophila MSL Complex Acetylates Histone H4 at Lysine 16, a Chromatin Modification Linked to Dosage Compensation | Molecular and Cellular Biology | 2000 | 304 |
| 45 | Widespread Rearrangement of 3D Chromatin Organization Underlies Polycomb-Mediated Stress-Induced Silencing | Molecular Cell | 2015 | 299 |
| 46 | Pharmacodynamic Functions: a Multiparameter Approach to the Design of Antibiotic Treatment Regimens | Antimicrobial Agents and Chemotherapy | 2004 | 298 |
| 47 | A Human Protein Complex Homologous to the Drosophila MSL Complex Is Responsible for the Majority of Histone H4 Acetylation at Lysine 16 | Molecular and Cellular Biology | 2005 | 292 |
| 48 | Synergy and Order Effects of Antibiotics and Phages in Killing Pseudomonas aeruginosa Biofilms | PLoS ONE | 2017 | 281 |
| 49 | Insulator function and topological domain border strength scale with architectural protein occupancy | Genome Biology | 2014 | 275 |
| 50 | The Population Genetics of Antibiotic Resistance | Clinical Infectious Diseases | 1997 | 267 |
