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Top Articles

#TitleJournalYearCitations
1Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,701
2Cellular Regulation of RGS Proteins: Modulators and Integrators of G Protein SignalingPharmacological Reviews2002655
3Distinct Role of Long 3′ UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal NeuronsCell2008604
4Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic dietAnnals of Neurology2006517
5α1Adrenoceptor subtypes linked to different mechanisms for increasing intracellular Ca2+ in smooth muscleNature1987492
6IL-4 Acts as a Myoblast Recruitment Factor during Mammalian Muscle GrowthCell2003446
7Myoblast fusion: lessons from flies and miceDevelopment (Cambridge)2012433
8Fine-tuning of GPCR activity by receptor-interacting proteinsNature Reviews Molecular Cell Biology2009413
9Control of proton sensitivity of the NMDA receptor by RNA splicing and polyaminesScience1995371
10Structural basis for partial agonist action at ionotropic glutamate receptorsNature Neuroscience2003364
11Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteinsProceedings of the National Academy of Sciences of the United States of America1999338
12Heterodimerization of G Protein-Coupled Receptors: Specificity and Functional SignificancePharmacological Reviews2005338
13Protein Kinase C Activation Regulates Human Serotonin Transporters in HEK-293 Cells via Altered Cell Surface ExpressionJournal of Neuroscience1997331
14NfatJournal of Cell Biology2002309
15Adenosine A2A receptor mediates microglial process retractionNature Neuroscience2009307
16Targeting protein–protein interactions as an anticancer strategyTrends in Pharmacological Sciences2013307
17Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loopNeuron1995289
18Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-D-aspartate (NMDA) receptor currents in hippocampal pyramidal cellsProceedings of the National Academy of Sciences of the United States of America1998255
19The COX-2 pathway is essential during early stages of skeletal muscle regenerationAmerican Journal of Physiology - Cell Physiology2004248
20GRIN2A mutation and early‐onset epileptic encephalopathy: personalized therapy with memantineAnnals of Clinical and Translational Neurology2014248
21Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gatingNature Neuroscience2011241
22Regulation of the Growth of Multinucleated Muscle Cells by an Nfatc2-Dependent PathwayJournal of Cell Biology2001230
23Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra culturesMolecular Brain Research2005227
24Automated, Quantitative Screening Assay for Antiangiogenic Compounds Using Transgenic ZebrafishCancer Research2007215
25Forming a Multinucleated Cell: Molecules That Regulate Myoblast FusionCells Tissues Organs2004211
26Commonalities in epileptogenic processes from different acute brain insults: Do they translate?Epilepsia2018206
27Optical Isomerism and Pharmacological Action, a GeneralizationScience1956200
28Activation of NR1/NR2B NMDA receptorsNature Neuroscience2003198
29Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicingGenes and Development2014193
30Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor proteinJournal of Biological Chemistry1989193
31The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemiaProceedings of the National Academy of Sciences of the United States of America2003190
32MOR23 Promotes Muscle Regeneration and Regulates Cell Adhesion and MigrationDevelopmental Cell2009189
33THE INHIBITION OF THE CONDITIONED RESPONSE AND THE COUNTERACTION OF SCHIZOPHRENIA BY MUSCARINIC STIMULATION OF THE BRAINAnnals of the New York Academy of Sciences1957184
34Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibitionNature Neuroscience1998171
35Effects of apomorphine, a dopamine receptor agonist, on ocular refraction and axial elongation in a primate model of myopiaInvestigative Ophthalmology and Visual Science1991166
36Regulation of catecholamine synthesis in the rat brain in vitro by cyclic AMPNature1974163
37Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivoProceedings of the National Academy of Sciences of the United States of America2014160
38Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptorsProceedings of the National Academy of Sciences of the United States of America2000158
39β1-Adrenergic Receptor Association with PSD-95Journal of Biological Chemistry2000155
40The N Terminus of the Adhesion G Protein-coupled Receptor GPR56 Controls Receptor Signaling ActivityJournal of Biological Chemistry2011153
41The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategiesNature Communications2017151
42The fast component in the electrical activity of rabbit's hippocampusElectroencephalography and Clinical Neurophysiology1965150
43QseC MediatesSalmonella entericaSerovar Typhimurium VirulenceIn VitroandIn VivoInfection and Immunity2010149
44Dopamine synthesis and metabolism in rhesus monkey retina: Development, aging, and the effects of monocular visual deprivationVisual Neuroscience1989147
45Overexpressed Human Mitochondrial Thioredoxin Confers Resistance to Oxidant-induced Apoptosis in Human Osteosarcoma CellsJournal of Biological Chemistry2002145
46A muscle precursor cell-dependent pathway contributes to muscle growth after atrophyAmerican Journal of Physiology - Cell Physiology2001143
47Cell Surface Expression of α1D-Adrenergic Receptors Is Controlled by Heterodimerization with α1B-Adrenergic ReceptorsJournal of Biological Chemistry2004143
48Prostaglandin F2α stimulates growth of skeletal muscle cells via an NFATC2-dependent pathwayJournal of Cell Biology2003140
49Protease-activated receptor-1 in human brain: localization and functional expression in astrocytesExperimental Neurology2004140
50Effects of narcotic antagonists on fluid intake in the ratLife Sciences1975138