| # | Title | Journal | Year | Citations |
|---|
| 1 | Pioglitazone attenuates mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation following traumatic brain injury | Experimental Neurology | 2011 | 134 |
| 2 | The effects of ginsenoside Rg1 on chronic stress induced depression-like behaviors, BDNF expression and the phosphorylation of PKA and CREB in rats | Neuroscience | 2016 | 97 |
| 3 | Structural basis of GPBAR activation and bile acid recognition | Nature | 2020 | 96 |
| 4 | Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes | Cell | 2021 | 94 |
| 5 | Effects of curcumin on chronic, unpredictable, mild, stress-induced depressive-like behaviour and structural plasticity in the lateral amygdala of rats | International Journal of Neuropsychopharmacology | 2014 | 93 |
| 6 | Neuroprotective Effects of Ginsenoside-Rg1 Against Depression-Like Behaviors via Suppressing Glial Activation, Synaptic Deficits, and Neuronal Apoptosis in Rats | Frontiers in Immunology | 2018 | 92 |
| 7 | Structures of the glucocorticoid-bound adhesion receptor GPR97–Go complex | Nature | 2021 | 90 |
| 8 | Hippocampal CA1 βCaMKII mediates neuroinflammatory responses via COX-2/PGE2 signaling pathways in depression | Journal of Neuroinflammation | 2018 | 88 |
| 9 | Curcumin produces antidepressant effects via activating MAPK/ERK-dependent brain-derived neurotrophic factor expression in the amygdala of mice | Behavioural Brain Research | 2012 | 81 |
| 10 | Hepatitis B virus core protein inhibits TRAIL-induced apoptosis of hepatocytes by blocking DR5 expression | Cell Death and Differentiation | 2009 | 78 |
| 11 | Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism | Cell Metabolism | 2020 | 77 |
| 12 | Neuroprotective Effects of Curcumin on IL-1β-Induced Neuronal Apoptosis and Depression-Like Behaviors Caused by Chronic Stress in Rats | Frontiers in Cellular Neuroscience | 2018 | 76 |
| 13 | The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ | Advanced Science | 2021 | 70 |
| 14 | Microglia secrete miR-146a-5p-containing exosomes to regulate neurogenesis in depression | Molecular Therapy | 2022 | 68 |
| 15 | Role of AMPA receptor trafficking in NMDA receptor‐dependent synaptic plasticity in the rat lateral amygdala | Journal of Neurochemistry | 2008 | 64 |
| 16 | NLRP3 inflammasome upregulates PD-L1 expression and contributes to immune suppression in lymphoma | Cancer Letters | 2021 | 63 |
| 17 | Structural basis for the tethered peptide activation of adhesion GPCRs | Nature | 2022 | 58 |
| 18 | Curcumin ameliorates memory deficits via neuronal nitric oxide synthase in aged mice | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2013 | 56 |
| 19 | GABAergic signaling facilitates breast cancer metastasis by promoting ERK1/2-dependent phosphorylation | Cancer Letters | 2014 | 55 |
| 20 | Ginsenoside Rg1 Prevents Chronic Stress-Induced Depression-Like Behaviors and Neuronal Structural Plasticity in Rats | Cellular Physiology and Biochemistry | 2018 | 55 |
| 21 | Chronic Unpredictable Mild Stress in Rats Induces Colonic Inflammation | Frontiers in Physiology | 2019 | 54 |
| 22 | Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site | Scientific Reports | 2013 | 53 |
| 23 | Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model | Neuropharmacology | 2022 | 53 |
| 24 | Curcumin Protects Against Chronic Stress-induced Dysregulation of Neuroplasticity and Depression-like Behaviors via Suppressing IL-1β Pathway in Rats | Neuroscience | 2018 | 51 |
| 25 | Neotrofin reverses the effects of chronic unpredictable mild stress on behavior via regulating BDNF, PSD-95 and synaptophysin expression in rat | Behavioural Brain Research | 2013 | 49 |
| 26 | Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p | Acta Biomaterialia | 2020 | 49 |
| 27 | Effects of progesterone on gastric emptying and intestinal transit in male rats | World Journal of Gastroenterology | 2002 | 47 |
| 28 | Understanding cadherin EGF LAG seven‐pass G‐type receptors | Journal of Neurochemistry | 2014 | 45 |
| 29 | MiR-134 modulates chronic stress-induced structural plasticity and depression-like behaviors via downregulation of Limk1/cofilin signaling in rats | Neuropharmacology | 2018 | 45 |
| 30 | Activation of GABAA Receptors in Colon Epithelium Exacerbates Acute Colitis | Frontiers in Immunology | 2018 | 43 |
| 31 | Different downstream signalling of CCK1 receptors regulates distinct functions of CCK in pancreatic beta cells | British Journal of Pharmacology | 2015 | 41 |
| 32 | Ginsenoside Rg1 reverses stress‐induced depression‐like behaviours and brain‐derived neurotrophic factor expression within the prefrontal cortex | European Journal of Neuroscience | 2016 | 41 |
| 33 | Overexpression of TRIM25 in Lung Cancer Regulates Tumor Cell Progression | Technology in Cancer Research and Treatment | 2016 | 40 |
| 34 | Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2 | Nature Communications | 2021 | 40 |
| 35 | G protein‐coupled estrogen receptor is involved in modulating colonic motor function via nitric oxide release in C57BL/6 female mice | Neurogastroenterology and Motility | 2016 | 39 |
| 36 | COX-2 inhibition rescues depression-like behaviors via suppressing glial activation, oxidative stress and neuronal apoptosis in rats | Neuropharmacology | 2019 | 37 |
| 37 | Neuronal activation by mucosal biopsy supernatants from irritable bowel syndrome patients is linked to visceral sensitivity | Experimental Physiology | 2014 | 36 |
| 38 | Oxytocin evokes a pulsatile PGE2 release from ileum mucosa and is required for repair of intestinal epithelium after injury | Scientific Reports | 2015 | 36 |
| 39 | NMDA GluN2B receptors involved in the antidepressant effects of curcumin in the forced swim test | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2013 | 35 |
| 40 | Apelin receptor homodimer-oligomers revealed by single-molecule imaging and novel G protein-dependent signaling | Scientific Reports | 2017 | 34 |
| 41 | FGF13 modulates the gating properties of the cardiac sodium channel Nav1.5 in an isoform-specific manner | Channels | 2016 | 33 |
| 42 | Mesenchymal stem cell-derived extracellular vesicles promote microglial M2 polarization after subarachnoid hemorrhage in rats and involve the AMPK/NF-κB signaling pathway | Biomedicine and Pharmacotherapy | 2021 | 33 |
| 43 | Unsaturated bond recognition leads to biased signal in a fatty acid receptor | Science | 2023 | 33 |
| 44 | Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress | Neural Regeneration Research | 2019 | 32 |
| 45 | Molecular mechanism of ERK dephosphorylation by striatal‐enriched protein tyrosine phosphatase | Journal of Neurochemistry | 2014 | 29 |
| 46 | Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype | Science Advances | 2021 | 28 |
| 47 | Curcumin ameliorates ethanol-induced memory deficits and enhanced brain nitric oxide synthase activity in mice | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2013 | 27 |
| 48 | Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade | Proceedings of the National Academy of Sciences of the United States of America | 2021 | 27 |
| 49 | Metal‐dependent protein phosphatase 1A functions as an extracellular signal‐regulated kinase phosphatase | FEBS Journal | 2013 | 26 |
| 50 | GRIM-19 opposes reprogramming of glioblastoma cell metabolism via HIF1α destabilization | Carcinogenesis | 2013 | 26 |
