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Top Articles

#TitleJournalYearCitations
1Advances in studies of tyrosine kinase inhibitors and their acquired resistanceMolecular Cancer2018255
2Gut Microbiota-Dependent Metabolite Trimethylamine N-Oxide Contributes to Cardiac Dysfunction in Western Diet-Induced Obese MiceFrontiers in Physiology2017191
3Human umbilical cord mesenchymal stem cells reduce systemic inflammation and attenuate LPS-induced acute lung injury in ratsJournal of Inflammation2012114
4The Potential Role of the NLRP3 Inflammasome Activation as a Link Between Mitochondria ROS Generation and Neuroinflammation in Postoperative Cognitive DysfunctionFrontiers in Cellular Neuroscience2019101
5Hydroxysafflor Yellow A Protects Against Cerebral Ischemia–Reperfusion Injury by Anti-apoptotic Effect Through PI3K/Akt/GSK3β Pathway in RatNeurochemical Research201382
6DTL promotes cancer progression by PDCD4 ubiquitin-dependent degradationJournal of Experimental and Clinical Cancer Research201968
7SKP2 promotes breast cancer tumorigenesis and radiation tolerance through PDCD4 ubiquitinationJournal of Experimental and Clinical Cancer Research201968
8Tetramethylpyrazine analogue CXC195 protects against cerebral ischemia/reperfusion-induced apoptosis through PI3K/Akt/GSK3β pathway in ratsNeurochemistry International201461
9HDAC11 Regulates Glycolysis through the LKB1/AMPK Signaling Pathway to Maintain Hepatocellular Carcinoma StemnessCancer Research202160
10Hyperin protects against LPS-induced acute kidney injury by inhibiting TLR4 and NLRP3 signaling pathwaysOncotarget201659
11Sevoflurane inhibits the migration and invasion of glioma cells by upregulating microRNA-637International Journal of Molecular Medicine201658
12Acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing BDNF expression and inhibiting neuroinflammation in the rat hippocampusNeuroscience Letters201555
13CUL4A overexpression enhances lung tumor growth and sensitizes lung cancer cells to Erlotinib via transcriptional regulation of EGFRMolecular Cancer201452
14miR-1204 targets VDR to promotes epithelial-mesenchymal transition and metastasis in breast cancerOncogene201852
15Propofol inhibits invasion and enhances paclitaxel- induced apoptosis in ovarian cancer cells through the suppression of the transcription factor slugEuropean Review for Medical and Pharmacological Sciences201351
16Neuroprotective Effects of Intravenous Lidocaine on Early Postoperative Cognitive Dysfunction in Elderly Patients Following Spine SurgeryMedical Science Monitor201545
17Propofol suppresses proliferation, invasion and angiogenesis by down-regulating ERK-VEGF/MMP-9 signaling in Eca-109 esophageal squamous cell carcinoma cellsEuropean Review for Medical and Pharmacological Sciences201344
18Activation of GABAA Receptors in Colon Epithelium Exacerbates Acute ColitisFrontiers in Immunology201843
19Histone demethylase JARID1C promotes breast cancer metastasis cells via down regulating BRMS1 expressionBiochemical and Biophysical Research Communications201540
20Attenuation of Neuropathic Pain by Saikosaponin a in a Rat Model of Chronic Constriction InjuryNeurochemical Research201438
21Metabolic reprogramming due to hypoxia in pancreatic cancer: Implications for tumor formation, immunity, and moreBiomedicine and Pharmacotherapy202133
22The Effects of Hispidulin on Bupivacaine-Induced Neurotoxicity: Role of AMPK Signaling PathwayCell Biochemistry and Biophysics201432
23Effects of sevoflurane post-conditioning in cerebral ischemia-reperfusion injury via TLR4/NF-κB pathway in ratsEuropean Review for Medical and Pharmacological Sciences201830
24KDM6B promotes ovarian cancer cell migration and invasion by induced transforming growth factor‐β1 expressionJournal of Cellular Biochemistry201929
25Transcriptional transactivator peptide modified lidocaine-loaded nanoparticulate drug delivery system for topical anesthetic therapyDrug Delivery201628
26Higher Circulating Trimethylamine N-oxide Sensitizes Sevoflurane-Induced Cognitive Dysfunction in Aged Rats Probably by Downregulating Hippocampal Methionine Sulfoxide Reductase ANeurochemical Research201928
27Decreased Brain KATP Channel Contributes to Exacerbating Ischemic Brain Injury and the Failure of Neuroprotection by Sevoflurane Post-Conditioning in Diabetic RatsPLoS ONE201327
28Nobiletin ameliorates isoflurane-induced cognitive impairment via antioxidant, anti-inflammatory and anti-apoptotic effects in aging ratsMolecular Medicine Reports201627
29The Inhibitory Effect of Lidocaine on the Release of High Mobility Group Box 1 in Lipopolysaccharide-Stimulated MacrophagesAnesthesia and Analgesia201126
30Increased expression of TROP2 in airway basal cells potentially contributes to airway remodeling in chronic obstructive pulmonary diseaseRespiratory Research201626
31Sevoflurane anesthesia represses neurogenesis of hippocampus neural stem cells via regulating microRNA‐183‐mediated NR4A2 in newborn ratsJournal of Cellular Physiology201926
32Sevoflurane Induces Exaggerated and Persistent Cognitive Decline in a Type II Diabetic Rat Model by Aggregating Hippocampal InflammationFrontiers in Pharmacology201724
33Anesthesiologist's knowledge and attitudes about obstructive sleep apnea: a survey studySleep and Breathing201223
34κB Activation">The Protective Effect of Lidocaine on Septic Rats via the Inhibition of High Mobility Group Box 1 Expression and NF-κB ActivationMediators of Inflammation201323
35Propofol Reduces Lipopolysaccharide-Induced, NADPH Oxidase (NOX2) Mediated TNF-αand IL-6 Production in MacrophagesClinical and Developmental Immunology201322
36Down-regulation of PPARα in the spinal cord contributes to augmented peripheral inflammation and inflammatory hyperalgesia in diet-induced obese ratsNeuroscience201422
37Propofol selectively inhibits nuclear factor-κB activity by suppressing p38 mitogen-activated protein kinase signaling in human EA.hy926 endothelial cells during intermittent hypoxia/reoxygenationMolecular Medicine Reports201422
38Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged RatsNeurochemical Research201622
39Propofol Protects Myocardium From Ischemia/Reperfusion Injury by Inhibiting Ferroptosis Through the AKT/p53 Signaling PathwayFrontiers in Pharmacology202222
40Pentoxifylline Ameliorates Cardiac Fibrosis, Pathological Hypertrophy, and Cardiac Dysfunction in Angiotensin II-induced Hypertensive RatsJournal of Cardiovascular Pharmacology201621
41Changes in intestinal microflora in digestive tract diseases during pregnancyArchives of Gynecology and Obstetrics202021
42Advances of immune checkpoints in colorectal cancer treatmentBiomedicine and Pharmacotherapy202021
43Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic IndividualsMediators of Inflammation202021
44Protein Phosphatase Magnesium-Dependent 1δ (PPM1D) mRNA Expression Is a Prognosis Marker for Hepatocellular CarcinomaPLoS ONE201320
45The Potential Roles of Exosomes in Chronic Obstructive Pulmonary DiseaseFrontiers in Medicine202020
46Betulin inhibits pro-inflammatory cytokines expression through activation STAT3 signaling pathway in human cardiac cellsEuropean Review for Medical and Pharmacological Sciences201520
47Effects of andrographolide on postoperative cognitive dysfunction and the association with NF‑κB/MAPK pathwayOncology Letters201719
48Protective role of p120‐catenin on mitochondria by inhibiting NLRP3 in ventilator‐induced lung injuryJournal of Cellular and Molecular Medicine201919
49Protective Effect of FTY720 Against Sevoflurane-Induced Developmental Neurotoxicity in RatsCell Biochemistry and Biophysics201318
50Chloroquine impairs visual transduction via modulation of acid sensing ion channel 1aToxicology Letters201418