| # | Title | Journal | Year | Citations |
|---|
| 1 | Establishment in culture of pluripotential cells from mouse embryos | Nature | 1981 | 7,627 |
| 2 | mCRY1 and mCRY2 Are Essential Components of the Negative Limb of the Circadian Clock Feedback Loop | Cell | 1999 | 1,445 |
| 3 | Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines | Nature | 1984 | 1,401 |
| 4 | Behavioral Theories and the Neurophysiology of Reward | Annual Review of Psychology | 2006 | 1,381 |
| 5 | α-Synuclein Is Degraded by Both Autophagy and the Proteasome | Journal of Biological Chemistry | 2003 | 1,246 |
| 6 | Interacting Molecular Loops in the Mammalian Circadian Clock | Science | 2000 | 1,223 |
| 7 | Placental-specific IGF-II is a major modulator of placental and fetal growth | Nature | 2002 | 961 |
| 8 | Leukocyte Infiltration, Neuronal Degeneration, and Neurite Outgrowth after Ablation of Scar-Forming, Reactive Astrocytes in Adult Transgenic Mice | Neuron | 1999 | 957 |
| 9 | Onset of Maternal Arterial Blood Flow and Placental Oxidative Stress | American Journal of Pathology | 2000 | 917 |
| 10 | Photoperiodic Control of Seasonality in Birds | Journal of Biological Rhythms | 2001 | 824 |
| 11 | A critical window for cooperation and competition among developing retinotectal synapses | Nature | 1998 | 815 |
| 12 | Differential Functions of mPer1, mPer2, and mPer3 in the SCN Circadian Clock | Neuron | 2001 | 802 |
| 13 | Chemotropic Responses of Retinal Growth Cones Mediated by Rapid Local Protein Synthesis and Degradation | Neuron | 2001 | 754 |
| 14 | The Polo kinase Plk4 functions in centriole duplication | Nature Cell Biology | 2005 | 740 |
| 15 | Circadian Cycling of the Mouse Liver Transcriptome, as Revealed by cDNA Microarray, Is Driven by the Suprachiasmatic Nucleus | Current Biology | 2002 | 711 |
| 16 | Effects of lesions to ascending noradrenergic neurones on performance of a 5-choice serial reaction task in rats; implications for theories of dorsal noradrenergic bundle function based on selective attention and arousal | Behavioural Brain Research | 1983 | 694 |
| 17 | Segmentation in the chick embryo hindbrain is defined by cell lineage restrictions | Nature | 1990 | 669 |
| 18 | Apoptosis Regulates Human Vascular Calcification In Vitro | Circulation Research | 2000 | 648 |
| 19 | Involvement of the amygdala in stimulus-reward associations: Interaction with the ventral striatum | Neuroscience | 1989 | 640 |
| 20 | Sexual motivation: A neural and behavioural analysis of the mechanisms underlying appetitive and copulatory responses of male rats | Neuroscience and Biobehavioral Reviews | 1990 | 598 |
| 21 | Complementary roles for the amygdala and hippocampus in aversive conditioning to explicit and contextual cues | Neuroscience | 1991 | 590 |
| 22 | Placental Oxidative Stress: From Miscarriage to Preeclampsia | Journal of the Society for Gynecologic Investigation | 2004 | 567 |
| 23 | Comparative Developmental Anatomy of the Murine and Human Definitive Placentae | Placenta | 2002 | 565 |
| 24 | Direct imaging of single-walled carbon nanotubes in cells | Nature Nanotechnology | 2007 | 539 |
| 25 | Fulminant Jejuno-Ileitis following Ablation of Enteric Glia in Adult Transgenic Mice | Cell | 1998 | 530 |
| 26 | The timed infusion paradigm for melatonin delivery: What has it taught us about the melatonin signal, its reception, and the photoperiodic control of seasonal responses? | Journal of Pineal Research | 1993 | 498 |
| 27 | The foundation of two distinct cell lineages within the mouse morula | Cell | 1981 | 476 |
| 28 | The basolateral amygdala-ventral striatal system and conditioned place preference: Further evidence of limbic-striatal interactions underlying reward-related processes | Neuroscience | 1991 | 475 |
| 29 | Beta-endorphin concentrations in cerebrospinal fluid of monkeys are influenced by grooming relationships | Psychoneuroendocrinology | 1989 | 472 |
| 30 | Specification of the vertebrate eye by a network of eye field transcription factors | Development (Cambridge) | 2003 | 471 |
| 31 | Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1 | Nature | 1999 | 465 |
| 32 | Visual transduction in Drosophila | Nature | 2001 | 465 |
| 33 | Neural coding of basic reward terms of animal learning theory, game theory, microeconomics and behavioural ecology | Current Opinion in Neurobiology | 2004 | 452 |
| 34 | Stochastic simulation of chemical reactions with spatial resolution and single molecule detail | Physical Biology | 2004 | 448 |
| 35 | Interactions between the amygdala and ventral striatum in stimulus-reward associations: Studies using a second-order schedule of sexual reinforcement | Neuroscience | 1989 | 447 |
| 36 | Uterine Glands Provide Histiotrophic Nutrition for the Human Fetus during the First Trimester of Pregnancy | Journal of Clinical Endocrinology and Metabolism | 2002 | 445 |
| 37 | Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12 | Nature Genetics | 2003 | 438 |
| 38 | Trophoblastic Oxidative Stress in Relation to Temporal and Regional Differences in Maternal Placental Blood Flow in Normal and Abnormal Early Pregnancies | American Journal of Pathology | 2003 | 437 |
| 39 | Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 407 |
| 40 | Comparative effects of ibotenic acid- and quisqualic acid-induced lesions of the substantia innominata on attentional function in the rat: further implications for the role of the cholinergic neurons of the nucleus basalis in cognitive processes | Behavioural Brain Research | 1989 | 404 |
| 41 | Maternal arterial connections to the placental intervillous space during the first trimester of human pregnancy: The Boyd Collection revisited | American Journal of Obstetrics and Gynecology | 1999 | 394 |
| 42 | Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL | Nature | 1999 | 390 |
| 43 | Imprinting and the Epigenetic Asymmetry Between Parental Genomes | Science | 2001 | 388 |
| 44 | Genetic Disorders of Vision Revealed by a Behavioral Screen of 400 Essential Loci in Zebrafish | Journal of Neuroscience | 1999 | 374 |
| 45 | Comparison of in vivo dissolution processes in hydroxyapatite and silicon-substituted hydroxyapatite bioceramics | Biomaterials | 2003 | 372 |
| 46 | Integrins in Development | Developmental Cell | 2002 | 362 |
| 47 | Cholinesterase-Containing Systems of the Brain of the Rat | Nature | 1963 | 360 |
| 48 | Recent life events, cortisol, dehydroepiandrosterone and the onset of major depression in high-risk adolescents | British Journal of Psychiatry | 2000 | 359 |
| 49 | Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues | Journal of Cell Science | 2001 | 348 |
| 50 | Functions of dopamine in the dorsal and ventral striatum | Seminars in Neuroscience | 1992 | 346 |
