| # | Title | Journal | Year | Citations |
|---|
| 1 | Low-Dose Inhaled Corticosteroids and the Prevention of Death from Asthma | New England Journal of Medicine | 2000 | 1,039 |
| 2 | Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy | Journal of Allergy and Clinical Immunology | 2011 | 424 |
| 3 | The Canadian Longitudinal Study on Aging (CLSA) | Canadian Journal on Aging | 2009 | 402 |
| 4 | Genome-wide association studies identify four ER negative–specific breast cancer risk loci | Nature Genetics | 2013 | 374 |
| 5 | Impact of preoperative change in physical function on postoperative recovery: Argument supporting prehabilitation for colorectal surgery | Surgery | 2011 | 362 |
| 6 | A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis | Arthritis Research and Therapy | 2008 | 349 |
| 7 | Correspondence analysis is a useful tool to uncover the relationships among categorical variables | Journal of Clinical Epidemiology | 2010 | 311 |
| 8 | Supervised and Unsupervised Self-Testing for HIV in High- and Low-Risk Populations: A Systematic Review | PLoS Medicine | 2013 | 285 |
| 9 | The role of functional social support in treatment retention and outcomes among outpatient adult substance abusers | Addiction | 2002 | 278 |
| 10 | Regular use of inhaled corticosteroids and the long term prevention of hospitalisation for asthma | Thorax | 2002 | 274 |
| 11 | Immediate and delayed impact of oral glucocorticoid therapy on risk of serious infection in older patients with rheumatoid arthritis: a nested case–control analysis | Annals of the Rheumatic Diseases | 2012 | 273 |
| 12 | Effectiveness of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease | American Journal of Respiratory and Critical Care Medicine | 2003 | 271 |
| 13 | Inhaled corticosteroids: Impact on asthma morbidity and mortality | Journal of Allergy and Clinical Immunology | 2001 | 265 |
| 14 | Anti-rheumatic drug use and risk of serious infections in rheumatoid arthritis | Rheumatology | 2007 | 246 |
| 15 | Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis | Lancet Respiratory Medicine,the | 2015 | 246 |
| 16 | Assessing the Diagnostic Properties of a Graded Oral Provocation Challenge for the Diagnosis of Immediate and Nonimmediate Reactions to Amoxicillin in Children | JAMA Pediatrics | 2016 | 237 |
| 17 | Sex Versus Gender-Related Characteristics | Journal of the American College of Cardiology | 2016 | 228 |
| 18 | Real-world comparative risks of herpes virus infections in tofacitinib and biologic-treated patients with rheumatoid arthritis | Annals of the Rheumatic Diseases | 2016 | 215 |
| 19 | Sex Differences in Stroke Risk Among Older Patients With Recently Diagnosed Atrial Fibrillation | JAMA - Journal of the American Medical Association | 2012 | 211 |
| 20 | Multilingualism (But Not Always Bilingualism) Delays the Onset of Alzheimer Disease: Evidence From a Bilingual Community | Alzheimer Disease and Associated Disorders | 2010 | 207 |
| 21 | A population-based study on peanut, tree nut, fish, shellfish, and sesame allergy prevalence in Canada | Journal of Allergy and Clinical Immunology | 2010 | 203 |
| 22 | Systematic review of outcomes used to evaluate enhanced recovery after surgery | British Journal of Surgery | 2014 | 191 |
| 23 | Proton pump inhibitor use and risk of community-acquired Clostridium difficile-associated disease defined by prescription for oral vancomycin therapy | Cmaj | 2006 | 187 |
| 24 | Anaphylaxis: past, present and future | Allergy: European Journal of Allergy and Clinical Immunology | 2011 | 180 |
| 25 | Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding | Cmaj | 2007 | 178 |
| 26 | A Longitudinal View of Apathy and Its Impact After Stroke | Stroke | 2009 | 176 |
| 27 | Assessing Spatial Variability of Ambient Nitrogen Dioxide in Montréal, Canada, with a Land-Use Regression Model | Journal of the Air and Waste Management Association | 2005 | 170 |
| 28 | Accidental ingestions in children with peanut allergy | Journal of Allergy and Clinical Immunology | 2006 | 169 |
| 29 | Development and Validation of a Tool to Improve Physician Identification of Elder Abuse: The Elder Abuse Suspicion Index (EASI)© | Journal of Elder Abuse and Neglect | 2008 | 162 |
| 30 | Primer: administrative health databases in observational studies of drug effects—advantages and disadvantages | Nature Clinical Practice Rheumatology | 2007 | 159 |
| 31 | Years of life lost and healthy life-years lost from diabetes and cardiovascular disease in overweight and obese people: a modelling study | Lancet Diabetes and Endocrinology,the | 2015 | 158 |
| 32 | Estimating the sensitivity and specificity of Kato-Katz stool examination technique for detection of hookworms, Ascaris lumbricoides and Trichuris trichiura infections in humans in the absence of a ‘gold standard’ | International Journal for Parasitology | 2010 | 157 |
| 33 | Inhaled and Nasal Corticosteroid Use and the Risk of Fracture | American Journal of Respiratory and Critical Care Medicine | 2004 | 146 |
| 34 | Health-related quality of life in postpartum depressed women | Archives of Women's Mental Health | 2006 | 141 |
| 35 | The relationship between cancer and medication exposures in systemic lupus erythaematosus: a case-cohort study | Annals of the Rheumatic Diseases | 2008 | 138 |
| 36 | Associations between neighbourhood walkability and daily steps in adults: a systematic review and meta-analysis | BMC Public Health | 2015 | 136 |
| 37 | Meta-analysis: proton-pump inhibition in high-risk patients with acute peptic ulcer bleeding | Alimentary Pharmacology and Therapeutics | 2005 | 130 |
| 38 | Exposure to traffic-related air pollution during physical activity and acute changes in blood pressure, autonomic and micro-vascular function in women: a cross-over study | Particle and Fibre Toxicology | 2014 | 130 |
| 39 | Statistical Treatment of Exacerbations in Therapeutic Trials of Chronic Obstructive Pulmonary Disease | American Journal of Respiratory and Critical Care Medicine | 2006 | 129 |
| 40 | Rates and risk factors associated with depressive symptoms during pregnancy and with postpartum onset | Journal of Psychosomatic Obstetrics and Gynaecology | 2014 | 129 |
| 41 | Atrophy and Fatty Infiltration of the Supraspinatus Muscle: Sonography Versus MRI | American Journal of Roentgenology | 2008 | 128 |
| 42 | Prevalence of peanut allergy in primary-school children in Montreal, Canada | Journal of Allergy and Clinical Immunology | 2003 | 126 |
| 43 | Statins and Cancer Risk | American Journal of Medicine | 2008 | 125 |
| 44 | Effect of tramiprosate in patients with mild-to-moderate alzheimer's disease: Exploratory analyses of the MRI sub-group of the alphase study | Journal of Nutrition, Health and Aging | 2009 | 122 |
| 45 | ACE-inhibitor use and the long-term risk of renal failure in diabetes | Kidney International | 2006 | 117 |
| 46 | The influence of systemic glucocorticoid therapy upon the risk of non-serious infection in older patients with rheumatoid arthritis: a nested case–control study | Annals of the Rheumatic Diseases | 2011 | 116 |
| 47 | Do digital innovations for HIV and sexually transmitted infections work? Results from a systematic review (1996-2017) | BMJ Open | 2017 | 116 |
| 48 | Lymphoma risk in systemic lupus: effects of disease activity versus treatment | Annals of the Rheumatic Diseases | 2014 | 115 |
| 49 | Hematologic Malignant Neoplasms After Drug Exposure in Rheumatoid Arthritis | Archives of Internal Medicine | 2008 | 112 |
| 50 | Self-reported leisure-time physical activity during pregnancy and relationship to psychological well-being | Journal of Psychosomatic Obstetrics and Gynaecology | 2003 | 111 |
