| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 2 | Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial | Lancet, The | 2012 | 1,041 |
| 3 | Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial | Lancet, The | 2012 | 1,040 |
| 4 | The efferent projections from the reticular formation and the locus coeruleus studied by anterograde and retrograde axonal transport in the rat | Journal of Comparative Neurology | 1985 | 914 |
| 5 | Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways | Science | 2015 | 823 |
| 6 | Discharge of Identified Orexin/Hypocretin Neurons across the Sleep-Waking Cycle | Journal of Neuroscience | 2005 | 778 |
| 7 | Common genetic variants influence human subcortical brain structures | Nature | 2015 | 772 |
| 8 | Phosphoinositides as Regulators in Membrane Traffic | Science | 1996 | 719 |
| 9 | Graded persistent activity in entorhinal cortex neurons | Nature | 2002 | 719 |
| 10 | Microglial control of astrocytes in response to microbial metabolites | Nature | 2018 | 693 |
| 11 | Functional localization and lateralization of human olfactory cortex | Nature | 1992 | 636 |
| 12 | Neuroblastoma × spinal cord (NSC) hybrid cell lines resemble developing motor neurons | Developmental Dynamics | 1992 | 628 |
| 13 | Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment | EMBO Reports | 2012 | 558 |
| 14 | Cortical Representation of the Sensory Dimension of Pain | Journal of Neurophysiology | 2001 | 549 |
| 15 | Astrocytes Are Endogenous Regulators of Basal Transmission at Central Synapses | Cell | 2011 | 536 |
| 16 | SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse | Neuron | 2019 | 518 |
| 17 | Neuronal morphometry directly from bitmap images | Nature Methods | 2014 | 517 |
| 18 | Genome-wide Analyses Identify KIF5A as a Novel ALS Gene | Neuron | 2018 | 517 |
| 19 | Afferents to the basal forebrain cholinergic cell area from pontomesencephalic—catecholamine, serotonin, and acetylcholine—neurons | Neuroscience | 1989 | 495 |
| 20 | The UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase gene is mutated in recessive hereditary inclusion body myopathy | Nature Genetics | 2001 | 476 |
| 21 | The NIH MRI study of normal brain development | NeuroImage | 2006 | 466 |
| 22 | Mutant Huntingtin Impairs Axonal Trafficking in Mammalian Neurons In Vivo and In Vitro | Molecular and Cellular Biology | 2004 | 454 |
| 23 | Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation | Science | 2013 | 440 |
| 24 | Cholinergic Basal Forebrain Neurons Burst with Theta during Waking and Paradoxical Sleep | Journal of Neuroscience | 2005 | 417 |
| 25 | Network and pharmacological mechanisms leading to epileptiform synchronization in the limbic system in vitro | Progress in Neurobiology | 2002 | 402 |
| 26 | Towards a Universal Taxonomy of Macro-scale Functional Human Brain Networks | Brain Topography | 2019 | 401 |
| 27 | Melanin-concentrating hormone neurons discharge in a reciprocal manner to orexin neurons across the sleep–wake cycle | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 394 |
| 28 | Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation | Nature Medicine | 2014 | 380 |
| 29 | Cooperative Astrocyte and Dendritic Spine Dynamics at Hippocampal Excitatory Synapses | Journal of Neuroscience | 2006 | 367 |
| 30 | Codistribution of GABA- with acetylcholine-synthesizing neurons in the basal forebrain of the rat | Journal of Comparative Neurology | 1993 | 363 |
| 31 | Netrins: versatile extracellular cues with diverse functions | Development (Cambridge) | 2011 | 363 |
| 32 | Heterogeneity within the frontoparietal control network and its relationship to the default and dorsal attention networks | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 363 |
| 33 | Generalized epilepsy: some of its cellular mechanisms differ from those of focal epilepsy | Trends in Neurosciences | 1988 | 361 |
| 34 | Frontal-lobe contribution to recency judgements | Neuropsychologia | 1991 | 344 |
| 35 | Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein | Nature Medicine | 2007 | 342 |
| 36 | Multiple sclerosis in children: clinical diagnosis, therapeutic strategies, and future directions | Lancet Neurology, The | 2007 | 341 |
| 37 | The Mitochondrial Transcription Factor TFAM Coordinates the Assembly of Multiple DNA Molecules into Nucleoid-like Structures | Molecular Biology of the Cell | 2007 | 340 |
| 38 | Interferon β-1b decreases the migration of T lymphocytes in vitro: Effects on matrix metalloproteinase-9 | Annals of Neurology | 1996 | 338 |
| 39 | Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP | Nature Cell Biology | 2001 | 337 |
| 40 | High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies | American Journal of Human Genetics | 2017 | 337 |
| 41 | Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39 | Nature Neuroscience | 2019 | 327 |
| 42 | The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications | Genes and Development | 2015 | 324 |
| 43 | Brain-immune connection: Immuno-regulatory properties of CNS-resident cells | Glia | 2000 | 323 |
| 44 | Utility of whole‐exome sequencing for those near the end of the diagnostic odyssey: time to address gaps in care | Clinical Genetics | 2016 | 323 |
| 45 | SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis | Journal of Biological Chemistry | 2021 | 316 |
| 46 | GABAergic neurons in the rat pontomesencephalic tegmentum: Codistribution with cholinergic and other tegmental neurons projecting to the posterior lateral hypothalamus | Journal of Comparative Neurology | 1995 | 315 |
| 47 | Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases | FEBS Letters | 1996 | 309 |
| 48 | BDNF Promotes the Regenerative Sprouting, But Not Survival, of Injured Serotonergic Axons in the Adult Rat Brain | Journal of Neuroscience | 2000 | 309 |
| 49 | Cellular isoform of the scrapie agent protein participates in lymphocyte activation | Cell | 1990 | 308 |
| 50 | Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS | Neuron | 2014 | 308 |
