| # | Title | Journal | Year | Citations |
|---|
| 1 | The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY | Nucleic Acids Research | 2018 | 1,584 |
| 2 | Reduced Vancomycin Susceptibility inStaphylococcus aureus, Including Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Strains: Resistance Mechanisms, Laboratory Detection, and Clinical Implications | Clinical Microbiology Reviews | 2010 | 804 |
| 3 | Nod-like proteins in immunity, inflammation and disease | Nature Immunology | 2006 | 794 |
| 4 | Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production | Antimicrobial Agents and Chemotherapy | 2010 | 699 |
| 5 | Toxin B is essential for virulence of Clostridium difficile | Nature | 2009 | 654 |
| 6 | Clostridium difficile infection | Nature Reviews Disease Primers | 2016 | 588 |
| 7 | Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes | Nature Immunology | 2017 | 551 |
| 8 | International Consensus Guidelines for the Optimal Use of the Polymyxins: Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti‐infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP) | Pharmacotherapy | 2019 | 545 |
| 9 | NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringens | PLoS Pathogens | 2008 | 494 |
| 10 | Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis | Genome Research | 2008 | 471 |
| 11 | Mechanisms involved in the resistance of Enterococcus faecalis to calcium hydroxide | International Endodontic Journal | 2002 | 457 |
| 12 | Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human Erythrocytes | Cell | 2008 | 450 |
| 13 | Targeted Gene Disruption Shows That Knobs Enable Malaria-Infected Red Cells to Cytoadhere under Physiological Shear Stress | Cell | 1997 | 398 |
| 14 | Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells | Cellular Microbiology | 2010 | 382 |
| 15 | Genetic Organization of Pasteurella multocida cap Loci and Development of a Multiplex Capsular PCR Typing System | Journal of Clinical Microbiology | 2001 | 378 |
| 16 | Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells | Immunity | 2019 | 378 |
| 17 | Roles of type IV pili, flagellum‐mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilms | Environmental Microbiology | 2008 | 345 |
| 18 | Molecular genetics and pathogenesis of Clostridium perfringens | Microbiological Reviews | 1991 | 343 |
| 19 | Towards an understanding of the role of Clostridium perfringens toxins in human and animal disease | Future Microbiology | 2014 | 328 |
| 20 | Pasteurella multocida pathogenesis: 125 years after Pasteur | FEMS Microbiology Letters | 2006 | 319 |
| 21 | Evolution of Multidrug Resistance during Staphylococcus aureus Infection Involves Mutation of the Essential Two Component Regulator WalKR | PLoS Pathogens | 2011 | 315 |
| 22 | Genome reduction in Leptospira borgpetersenii reflects limited transmission potential | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 309 |
| 23 | Virulence studies on chromosomal ?-toxin and ?-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of ?-toxin in Clostridium perfringens-mediated gas gangrene | Molecular Microbiology | 1995 | 303 |
| 24 | VIRULENCE GENES OFCLOSTRIDIUM PERFRINGENS | Annual Review of Microbiology | 1998 | 303 |
| 25 | Efflux‐mediated antiseptic resistance gene qacA from Staphylococcus aureus: common ancestry with tetracycline‐ and sugar‐transport proteins | Molecular Microbiology | 1990 | 300 |
| 26 | Primary biliary cirrhosis | Lancet, The | 2011 | 294 |
| 27 | Mesenchymal Stem Cells Deliver Exogenous MicroRNA-let7c via Exosomes to Attenuate Renal Fibrosis | Molecular Therapy | 2016 | 286 |
| 28 | Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium | Hepatology | 2003 | 281 |
| 29 | Nod1-Mediated Innate Immune Recognition of Peptidoglycan Contributes to the Onset of Adaptive Immunity | Immunity | 2007 | 281 |
| 30 | Identification of HLA-A2–restricted CD8+ Cytotoxic T Cell Responses in Primary Biliary Cirrhosis | Journal of Experimental Medicine | 2002 | 278 |
| 31 | Contribution of parasite proteins to altered mechanical properties of malaria-infected red blood cells | Blood | 2002 | 276 |
| 32 | Adhesion of Plasmodium falciparum-infected erythrocytes to hyaluronic acid in placental malaria | Nature Medicine | 2000 | 275 |
| 33 | Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis | Hepatology | 2006 | 274 |
| 34 | The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments | Immunity | 2012 | 272 |
| 35 | Nucleotide and Complete Amino Acid Sequences of Kunjin Virus: Definitive Gene Order and Characteristics of the Virus-specified Proteins | Journal of General Virology | 1988 | 267 |
| 36 | A Common Fold Mediates Vertebrate Defense and Bacterial Attack | Science | 2007 | 261 |
| 37 | Emerging rules for effective antimicrobial coatings | Trends in Biotechnology | 2014 | 257 |
| 38 | Leptospirosis in the Asia Pacific region | BMC Infectious Diseases | 2009 | 254 |
| 39 | What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira | PLoS Neglected Tropical Diseases | 2016 | 253 |
| 40 | Human Antibodies Fix Complement to Inhibit Plasmodium falciparum Invasion of Erythrocytes and Are Associated with Protection against Malaria | Immunity | 2015 | 250 |
| 41 | Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond | PLoS Pathogens | 2016 | 244 |
| 42 | Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation | Science Translational Medicine | 2016 | 241 |
| 43 | Molecular genetics and pathogenesis of Clostridium perfringens. | Microbiological Reviews | 1991 | 234 |
| 44 | Acinetobacter baumannii: Evolution of Antimicrobial Resistance—Treatment Options | Seminars in Respiratory and Critical Care Medicine | 2015 | 233 |
| 45 | Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections | MBio | 2015 | 228 |
| 46 | Alpha-Toxin of Clostridium perfringens Is Not an Essential Virulence Factor in Necrotic Enteritis in Chickens | Infection and Immunity | 2006 | 226 |
| 47 | Crystal Structure of the RNA Polymerase Domain of the West Nile Virus Non-structural Protein 5 | Journal of Biological Chemistry | 2007 | 222 |
| 48 | Revised nomenclature for transposable genetic elements | Plasmid | 2008 | 222 |
| 49 | The Mechanisms of Disease Caused by Acinetobacter baumannii | Frontiers in Microbiology | 2019 | 220 |
| 50 | IL-2 receptor α−/− mice and the development of primary biliary cirrhosis | Hepatology | 2006 | 219 |
