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Department of Biochemistry and Cambridge Systems Biology Centre
›
top-articles
Department of Biochemistry and Cambridge Systems Biology Centre
86
(top 1%)
papers
5.1K
(top 1%)
citations
37
(top 1%)
h
-index
72
(top 1%)
g
-index
96
all documents
5.8K
doc citations
1.5K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
Chemical Society Reviews
2011
689
2
Remaining Mysteries of Molecular Biology: The Role of Polyamines in the Cell
Journal of Molecular Biology
2015
508
3
Toward interoperable bioscience data
Nature Genetics
2012
362
4
HIF1
α
Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1–3 and PKM2
Stem Cells
2014
226
5
Cytosine DNA Methylation Is Found in
Drosophila melanogaster
but Absent in
Saccharomyces cerevisiae, Schizosaccharomyces pombe
, and Other Yeast Species
Analytical Chemistry
2014
225
6
Drosophila Ionotropic Receptor 25a mediates circadian clock resetting by temperature
Nature
2015
216
7
Non‐enzymatic glycolysis and pentose phosphate pathway‐like reactions in a plausible
A
rchean ocean
Molecular Systems Biology
2014
182
8
Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease
Hepatology
2017
138
9
Functional Metabolomics Describes the Yeast Biosynthetic Regulome
Cell
2016
137
10
Metabolic profiling detects biomarkers of protein degradation in COPD patients
European Respiratory Journal
2012
128
11
Inorganic Nitrate Promotes the Browning of White Adipose Tissue Through the Nitrate-Nitrite-Nitric Oxide Pathway
Diabetes
2015
121
12
Unbiased Metabolomic Investigation of Alzheimer’s Disease Brain Points to Dysregulation of Mitochondrial Aspartate Metabolism
Journal of Proteome Research
2016
107
13
The widespread role of non-enzymatic reactions in cellular metabolism
Current Opinion in Biotechnology
2015
105
14
The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization
Nature Communications
2017
95
15
Methionine Metabolism Alters Oxidative Stress Resistance
via
the Pentose Phosphate Pathway
Antioxidants and Redox Signaling
2016
93
16
Sulfate radicals enable a non-enzymatic Krebs cycle precursor
Nature Ecology and Evolution
2017
88
17
The
Saccharomyces cerevisiae
W303-K6001 cross-platform genome sequence: insights into ancestry and physiology of a laboratory mutt
Open Biology
2012
87
18
The potential of Ion Mobility Mass Spectrometry for high-throughput and high-resolution lipidomics
Current Opinion in Chemical Biology
2018
81
19
Machine Learning Predicts the Yeast Metabolome from the Quantitative Proteome of Kinase Knockouts
Cell Systems
2018
80
20
The metabolic background is a global player in Saccharomyces gene expression epistasis
Nature Microbiology
2016
76
21
Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma
Hepatology
2021
76
22
Mitochondria in ageing: there is metabolism beyond the ROS
FEMS Yeast Research
2014
71
23
Metabolomics of the interaction between PPAR‐α and age in the PPAR‐α‐null mouse
Molecular Systems Biology
2009
69
24
An appeal to magic? The discovery of a non-enzymatic metabolism and its role in the origins of life
Biochemical Journal
2018
69
25
The PHD and Chromo Domains Regulate the ATPase Activity of the Human Chromatin Remodeler CHD4
Journal of Molecular Biology
2012
68
26
MitoLoc: A method for the simultaneous quantification of mitochondrial network morphology and membrane potential in single cells
Mitochondrion
2015
68
27
Cost-effective generation of precise label-free quantitative proteomes in high-throughput by microLC and data-independent acquisition
Scientific Reports
2018
66
28
Deletion of Stearoyl-CoA Desaturase-1 From the Intestinal Epithelium Promotes Inflammation and Tumorigenesis, Reversed by Dietary Oleate
Gastroenterology
2018
66
29
Conditional iron and pH-dependent activity of a non-enzymatic glycolysis and pentose phosphate pathway
Science Advances
2016
65
30
Dietary inorganic nitrate: From villain to hero in metabolic disease?
Molecular Nutrition and Food Research
2016
59
31
Liver‐Specific Deletion of Mouse Tm6sf2 Promotes Steatosis, Fibrosis, and Hepatocellular Cancer
Hepatology
2021
57
32
A gatekeeper helix determines the substrate specificity of Sjögren–Larsson Syndrome enzyme fatty aldehyde dehydrogenase
Nature Communications
2014
55
33
An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors
Journal of Proteome Research
2019
55
34
Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome
Proceedings of the National Academy of Sciences of the United States of America
2015
50
35
Nonenzymatic gluconeogenesis-like formation of fructose 1,6-bisphosphate in ice
Proceedings of the National Academy of Sciences of the United States of America
2017
48
36
Liquid Extraction Surface Analysis Mass Spectrometry Method for Identifying the Presence and Severity of Nonalcoholic Fatty Liver Disease
Analytical Chemistry
2017
47
37
N‐terminomics reveals control of Arabidopsis seed storage proteins and proteases by the Arg/N‐end rule pathway
New Phytologist
2018
44
38
Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation
JCI Insight
2017
42
39
FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle
Cell
2020
42
40
A role for vaccinia virus protein C16 in reprogramming cellular energy metabolism
Journal of General Virology
2015
41
41
Cell‐to‐cell heterogeneity emerges as consequence of metabolic cooperation in a synthetic yeast community
Biotechnology Journal
2016
41
42
KniMet: a pipeline for the processing of chromatography–mass spectrometry metabolomics data
Metabolomics
2018
40
43
A Comprehensive UHPLC Ion Mobility Quadrupole Time-of-Flight Method for Profiling and Quantification of Eicosanoids, Other Oxylipins, and Fatty Acids
Analytical Chemistry
2019
40
44
Italian cohort of patients affected by inflammatory bowel disease is characterised by variation in glycerophospholipid, free fatty acids and amino acid levels
Metabolomics
2018
39
45
Sacrifice for survival
Nature
2011
35
46
Inorganic Nitrate Mimics Exercise-Stimulated Muscular Fiber-Type Switching and Myokine and γ-Aminobutyric Acid Release
Diabetes
2017
35
47
A gas chromatography-mass spectrometry untargeted metabolomics approach to discriminate Fiore Sardo cheese produced from raw or thermized ovine milk
Journal of Dairy Science
2019
31
48
Metabolomic and lipidomic plasma profile changes in human participants ascending to Everest Base Camp
Scientific Reports
2019
31
49
Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis
Nature Metabolism
2020
31
50
An Integrated Model of Transcription Factor Diffusion Shows the Importance of Intersegmental Transfer and Quaternary Protein Structure for Target Site Finding
PLoS ONE
2014
31
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