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Top Articles

#TitleJournalYearCitations
1Derivation of pluripotent epiblast stem cells from mammalian embryosNature20071,842
2Human primary liver cancer–derived organoid cultures for disease modeling and drug screeningNature Medicine2017905
3Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cellsJournal of Cell Science2005852
4Cells of the adult human heartNature2020852
5Induction of Immunological Tolerance by Porcine Liver AllograftsNature1969818
6A randomized trial of normothermic preservation in liver transplantationNature2018804
7Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cellsNature2011635
8A cellular census of human lungs identifies novel cell states in health and in asthmaNature Medicine2019631
9scRNA-seq assessment of the human lung, spleen, and esophagus tissue stability after cold preservationGenome Biology2020572
10The generation of transgenic pigs as potential organ donors for humansNature Medicine1995563
11ORTHOTOPIC LIVER TRANSPLANTATION IN THE RATTransplantation1979549
12The Cell-Cycle State of Stem Cells Determines Cell Fate PropensityCell2013541
13Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumorsScience2018511
14Common genetic variation drives molecular heterogeneity in human iPSCsNature2017491
15The landscape of somatic mutation in normal colorectal epithelial cellsNature2019468
16Banking on human embryonic stem cells: estimating the number of donor cell lines needed for HLA matchingLancet, The2005456
17Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transitionNature2016443
18Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx RenalCell2018398
19A cell atlas of human thymic development defines T cell repertoire formationScience2020368
20Immunosuppressive agents in solid organ transplantation: Mechanisms of action and therapeutic efficacyCritical Reviews in Oncology/Hematology2005363
21Generating an iPSC Bank for HLA-Matched Tissue Transplantation Based on Known Donor and Recipient HLA TypesCell Stem Cell2012350
22The mutational landscape of normal human endometrial epitheliumNature2020338
23Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathwayDevelopmental Biology2004330
24GDF15 mediates the effects of metformin on body weight and energy balanceNature2020326
25Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validationNature Biotechnology2015318
26Genome editing reveals a role for OCT4 in human embryogenesisNature2017315
27Analysis of factors that affect outcome after transplantation of kidneys donated after cardiac death in the UK: a cohort studyLancet, The2010306
28Production of hepatocyte-like cells from human pluripotent stem cellsNature Protocols2013292
29The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotencyNature2018283
30High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitisNature Genetics2015280
31Cells of the human intestinal tract mapped across space and timeNature2021266
32Cross-tissue immune cell analysis reveals tissue-specific features in humansScience2022265
33Kidney donation after circulatory death (DCD): state of the artKidney International2015264
34Observations on the ex situ perfusion of livers for transplantationAmerican Journal of Transplantation2018260
35Compromised lymphocytes infiltrate hepatocellular carcinoma: The role of T-regulatory cellsHepatology2005255
36Somatic mutation landscapes at single-molecule resolutionNature2021254
37Effect of sirolimus on malignancy and survival after kidney transplantation: systematic review and meta-analysis of individual patient dataBMJ, The2014252
38LIFE-SUPPORTING PIG-TO-PRIMATE RENAL XENOTRANSPLANTATION USING GENETICALLY MODIFIED DONORSTransplantation1998247
39Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viabilityNature Communications2015241
40Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitroNature Genetics2021238
41Outcome after heart transplantation from donation after circulatory-determined death donorsJournal of Heart and Lung Transplantation2017235
42Interaction of Salmonella enterica Serovar Typhimurium with Intestinal Organoids Derived from Human Induced Pluripotent Stem CellsInfection and Immunity2015221
43Alemtuzumab (CAMPATH 1H) Induction Therapy in Cadaveric Kidney Transplantation-Efficacy and Safety at Five YearsAmerican Journal of Transplantation2005213
44Effect of donor age and cold storage time on outcome in recipients of kidneys donated after circulatory death in the UK: a cohort studyLancet, The2013212
45Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoidsNature Medicine2017210
46Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programmingNature Communications2016199
47Extensive heterogeneity in somatic mutation and selection in the human bladderScience2020195
48Cold Machine Perfusion Versus Static Cold Storage of Kidneys Donated After Cardiac Death: A UK Multicenter Randomized Controlled TrialAmerican Journal of Transplantation2010190
49In situ normothermic perfusion of livers in controlled circulatory death donation may prevent ischemic cholangiopathy and improve graft survivalAmerican Journal of Transplantation2019190
50SIROLIMUS: A POTENT NEW IMMUNOSUPPRESSANT FOR LIVER TRANSPLANTATIONTransplantation1999190