| # | Title | Journal | Year | Citations |
|---|
| 1 | The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups | Nature | 2012 | 4,708 |
| 2 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 3 | Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies | American Journal of Human Genetics | 2003 | 3,105 |
| 4 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,634 |
| 5 | Genome-wide association study identifies novel breast cancer susceptibility loci | Nature | 2007 | 2,165 |
| 6 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 7 | Hundreds of variants clustered in genomic loci and biological pathways affect human height | Nature | 2010 | 1,789 |
| 8 | Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial | Lancet, The | 2010 | 1,596 |
| 9 | Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial | Lancet, The | 2010 | 1,584 |
| 10 | Relative Impact of Nucleotide and Copy Number Variation on Gene Expression Phenotypes | Science | 2007 | 1,546 |
| 11 | Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 1,471 |
| 12 | A framework for oligonucleotide microarray preprocessing | Bioinformatics | 2010 | 1,327 |
| 13 | The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes | Nature Communications | 2016 | 1,221 |
| 14 | Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1 | Nature Genetics | 2008 | 1,189 |
| 15 | The evolutionary history of lethal metastatic prostate cancer | Nature | 2015 | 1,185 |
| 16 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
| 17 | Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA | Science Translational Medicine | 2012 | 1,086 |
| 18 | Population genomics of human gene expression | Nature Genetics | 2007 | 1,072 |
| 19 | Large-scale genotyping identifies 41 new loci associated with breast cancer risk | Nature Genetics | 2013 | 960 |
| 20 | A comparison of background correction methods for two-colour microarrays | Bioinformatics | 2007 | 829 |
| 21 | MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype | Genome Biology | 2007 | 828 |
| 22 | Multiple newly identified loci associated with prostate cancer susceptibility | Nature Genetics | 2008 | 796 |
| 23 | Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies | PLoS Medicine | 2010 | 764 |
| 24 | CD133, a novel marker for human prostatic epithelial stem cells | Journal of Cell Science | 2004 | 714 |
| 25 | Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes | American Journal of Human Genetics | 2019 | 711 |
| 26 | Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data | Lancet Oncology, The | 2014 | 703 |
| 27 | Beyond GWASs: Illuminating the Dark Road from Association to Function | American Journal of Human Genetics | 2013 | 688 |
| 28 | Genome-wide association study identifies five new breast cancer susceptibility loci | Nature Genetics | 2010 | 653 |
| 29 | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci | Nature Genetics | 2018 | 652 |
| 30 | A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis | Nature Biotechnology | 2008 | 619 |
| 31 | Maximizing mouse cancer models | Nature Reviews Cancer | 2007 | 617 |
| 32 | A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2 | Nature Medicine | 2003 | 616 |
| 33 | Toward understanding and exploiting tumor heterogeneity | Nature Medicine | 2015 | 604 |
| 34 | Progress in matrix metalloproteinase research | Molecular Aspects of Medicine | 2008 | 593 |
| 35 | AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol | Cancer Cell | 2003 | 585 |
| 36 | Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families | Gastroenterology | 2001 | 579 |
| 37 | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture | Nature Genetics | 2013 | 578 |
| 38 | Polygenes, Risk Prediction, and Targeted Prevention of Breast Cancer | New England Journal of Medicine | 2008 | 558 |
| 39 | Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche | Nature | 2014 | 548 |
| 40 | Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution | Nature | 2015 | 545 |
| 41 | Rare and low-frequency coding variants alter human adult height | Nature | 2017 | 544 |
| 42 | Mutations truncating the EP300 acetylase in human cancers | Nature Genetics | 2000 | 543 |
| 43 | Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 | Nature Genetics | 2008 | 542 |
| 44 | Waves of Retrotransposon Expansion Remodel Genome Organization and CTCF Binding in Multiple Mammalian Lineages | Cell | 2012 | 528 |
| 45 | Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer | Nature Genetics | 2015 | 513 |
| 46 | Common 5p15.33 and 6p21.33 variants influence lung cancer risk | Nature Genetics | 2008 | 510 |
| 47 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer | Nature Genetics | 2013 | 493 |
| 48 | Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array | Nature Genetics | 2013 | 492 |
| 49 | A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma | American Journal of Human Genetics | 2009 | 489 |
| 50 | Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germlineCDH1mutation carriers | Journal of Medical Genetics | 2015 | 479 |
