| # | Title | Journal | Year | Citations |
|---|
| 1 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 9,397 |
| 2 | Multiple imputation using chained equations: Issues and guidance for practice | Statistics in Medicine | 2011 | 6,168 |
| 3 | Global prevalence of dementia: a Delphi consensus study | Lancet, The | 2005 | 4,496 |
| 4 | Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator | Genetic Epidemiology | 2016 | 4,142 |
| 5 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 6 | Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies | Lancet, The | 2010 | 3,807 |
| 7 | The MR-Base platform supports systematic causal inference across the human phenome | ELife | 2018 | 3,639 |
| 8 | Process evaluation of complex interventions: Medical Research Council guidance | BMJ, The | 2015 | 3,602 |
| 9 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,249 |
| 10 | Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data | Genetic Epidemiology | 2013 | 2,705 |
| 11 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 12 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,634 |
| 13 | C-Reactive Protein and Other Circulating Markers of Inflammation in the Prediction of Coronary Heart Disease | New England Journal of Medicine | 2004 | 2,608 |
| 14 | Genome-wide association study identifies novel breast cancer susceptibility loci | Nature | 2007 | 2,165 |
| 15 | C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis | Lancet, The | 2010 | 1,946 |
| 16 | Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study | Lancet, The | 2012 | 1,937 |
| 17 | Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers | JAMA - Journal of the American Medical Association | 2017 | 1,898 |
| 18 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 19 | Serious mental disorder in 23 000 prisoners: a systematic review of 62 surveys | Lancet, The | 2002 | 1,783 |
| 20 | 2019 ESC/EAS guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk | Atherosclerosis | 2019 | 1,753 |
| 21 | Prevalence of serious mental disorder in 7000 refugees resettled in western countries: a systematic review | Lancet, The | 2005 | 1,708 |
| 22 | Interpreting findings from Mendelian randomization using the MR-Egger method | European Journal of Epidemiology | 2017 | 1,696 |
| 23 | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease | Nature Genetics | 2011 | 1,685 |
| 24 | Large-scale association analysis identifies new risk loci for coronary artery disease | Nature Genetics | 2013 | 1,439 |
| 25 | Interpretation of the evidence for the efficacy and safety of statin therapy | Lancet, The | 2016 | 1,399 |
| 26 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 27 | Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials | Lancet, The | 2009 | 1,234 |
| 28 | Triglycerides and the Risk of Coronary Heart Disease | Circulation | 2007 | 1,216 |
| 29 | Genomic atlas of the human plasma proteome | Nature | 2018 | 1,180 |
| 30 | Common variants near MC4R are associated with fat mass, weight and risk of obesity | Nature Genetics | 2008 | 1,179 |
| 31 | MendelianRandomization: an R package for performing Mendelian randomization analyses using summarized data | International Journal of Epidemiology | 2017 | 1,178 |
| 32 | A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25 | Nature | 2008 | 1,169 |
| 33 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,124 |
| 34 | British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus | Gut | 2014 | 1,116 |
| 35 | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture | Nature Genetics | 2012 | 1,100 |
| 36 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
| 37 | A systematic review of prevalence studies of dementia in Parkinson's disease | Movement Disorders | 2005 | 1,060 |
| 38 | The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease | Cell | 2016 | 1,052 |
| 39 | PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations | Bioinformatics | 2019 | 1,036 |
| 40 | PhenoScanner: a database of human genotype–phenotype associations | Bioinformatics | 2016 | 983 |
| 41 | Bias due to participant overlap in two‐sample Mendelian randomization | Genetic Epidemiology | 2016 | 961 |
| 42 | Large-scale genotyping identifies 41 new loci associated with breast cancer risk | Nature Genetics | 2013 | 960 |
| 43 | Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility | Nature Genetics | 2014 | 959 |
| 44 | The genetic architecture of type 2 diabetes | Nature | 2016 | 952 |
| 45 | Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies | Lancet, The | 2011 | 941 |
| 46 | Plasma Fibrinogen Level and the Risk of Major Cardiovascular Diseases and Nonvascular Mortality | JAMA - Journal of the American Medical Association | 2005 | 925 |
| 47 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 48 | Prevalence of Depression and Depressive Symptoms Among Resident Physicians | JAMA - Journal of the American Medical Association | 2015 | 886 |
| 49 | Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies | Lancet, The | 2018 | 858 |
| 50 | The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort | Brain | 2009 | 842 |
