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Top Articles

#TitleJournalYearCitations
1Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
2Atg2 mediates direct lipid transfer between membranes for autophagosome formationNature Structural and Molecular Biology2019312
3Phase separation organizes the site of autophagosome formationNature2020263
4Atg9 is a lipid scramblase that mediates autophagosomal membrane expansionNature Structural and Molecular Biology2020253
5Single nucleosome imaging reveals loose genome chromatin networks via active RNA polymerase IIJournal of Cell Biology2019162
6Cohesin and condensin extrude DNA loops in a cell cycle-dependent mannerELife2020158
7Wetting regulates autophagy of phase-separated compartments and the cytosolNature2021140
8A chromatin integration labelling method enables epigenomic profiling with lower inputNature Cell Biology2019121
9Liquidity Is a Critical Determinant for Selective Autophagy of Protein CondensatesMolecular Cell2020118
10HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndromeProceedings of the National Academy of Sciences of the United States of America201888
11Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2Molecular Cell201887
12Unveiling the molecular mechanisms of plant autophagy – from autophagosomes to vacuoles in plantsPlant and Cell Physiology201883
13Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live-cell analysisDevelopment (Cambridge)201981
14A genetically encoded probe for imaging nascent and mature HA-tagged proteins in vivoNature Communications201972
15Intrinsic Ribosome Destabilization Underlies Translation and Provides an Organism with a Strategy of Environmental SensingMolecular Cell201768
16Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cellsScience Advances202066
17The NSL complex maintains nuclear architecture stability via lamin A/C acetylationNature Cell Biology201961
18Proximity Histidine Labeling by Umpolung Strategy Using Singlet OxygenJournal of the American Chemical Society202160
19Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosomeNucleic Acids Research201858
20Autophagy induction under carbon starvation conditions is negatively regulated by carbon catabolite repressionJournal of Biological Chemistry201757
21Deubiquitinases USP5 and USP13 are recruited to and regulate heat-induced stress granules by deubiquitinating activitiesJournal of Cell Science201856
22Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranesNature Communications202054
23Protein Nanotube Selectively Cleavable with DNA: Supramolecular Polymerization of “DNA-Appended Molecular Chaperones”Journal of the American Chemical Society201853
24Membrane perturbation by lipidated Atg8 underlies autophagosome biogenesisNature Structural and Molecular Biology202151
25Ub-ProT reveals global length and composition of protein ubiquitylation in cellsNature Communications201850
26H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2Genome Research201843
27Single-molecule imaging reveals control of parental histone recycling by free histones during DNA replicationScience Advances202043
28H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencingEMBO Reports202140
29The first successful observation of in-cell NMR signals of DNA and RNA in living human cellsPhysical Chemistry Chemical Physics201837
30Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cellsEMBO Journal202037
31Selectivity of mRNA degradation by autophagy in yeastNature Communications202135
32JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin statesEpigenetics201832
33Analysis of autophagy activated during changes in carbon source availability in yeast cellsJournal of Biological Chemistry201931
34C9orf72-derived arginine-rich poly-dipeptides impede phase modifiersNature Communications202131
35The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphismNature Communications201928
36Single-cell profiling of transcriptome and histone modifications with EpiDamIDMolecular Cell202228
37Large-scale aggregation analysis of eukaryotic proteins reveals an involvement of intrinsically disordered regions in protein foldingScientific Reports201826
38Reduction in chromosome mobility accompanies nuclear organization during early embryogenesis in Caenorhabditis elegansScientific Reports201724
39Inhibition of RIF1 by SCAI Allows BRCA1-Mediated RepairCell Reports201724
40Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcriptionCommunications Biology201924
41Live-cell epigenome manipulation by synthetic histone acetylation catalyst systemProceedings of the National Academy of Sciences of the United States of America202124
42Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regenerationNature Communications201823
43The integral function of endocytic recycling compartment is regulated by RFFL-mediated ubiquitination of Rab11 effectorsJournal of Cell Science201923
44Kinase inhibition profiles as a tool to identify kinases for specific phosphorylation sitesNature Communications202022
45Live imaging of transcription sites using an elongating RNA polymerase II–specific probeJournal of Cell Biology202222
46Autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolismNature Communications202021
47Cyclization of Single-Chain Fv Antibodies Markedly Suppressed Their Characteristic Aggregation Mediated by Inter-Chain VH-VL InteractionsMolecules201920
48Escherichia coli small heat shock protein IbpA is an aggregation‐sensor that self‐regulates its own expression at posttranscriptional levelsMolecular Microbiology202119
49High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq)Journal of Cell Biology202119
50Incorporation and influence of Leishmania histone H3 in chromatinNucleic Acids Research201918