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top-articles
Medical Department
958
(top 1%)
papers
62.0K
(top 0.1%)
citations
115
(top 0.1%)
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221
(top 0.1%)
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1.0K
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64.5K
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5.8K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
A simple technique for quantitation of low levels of DNA damage in individual cells
Experimental Cell Research
1988
9,283
2
Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications
Nature Reviews Neuroscience
2011
2,029
3
Dopamine in drug abuse and addiction: results from imaging studies and treatment implications
Molecular Psychiatry
2004
870
4
Low Level of Brain Dopamine D2Receptors in Methamphetamine Abusers: Association With Metabolism in the Orbitofrontal Cortex
American Journal of Psychiatry
2001
840
5
Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers
Synapse
1993
836
6
Dopamine Transporter Occupancies in the Human Brain Induced by Therapeutic Doses of Oral Methylphenidate
American Journal of Psychiatry
1998
826
7
Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects
Nature
1997
794
8
Addiction: Beyond dopamine reward circuitry
Proceedings of the National Academy of Sciences of the United States of America
2011
733
9
Relationship between subjective effects of cocaine and dopamine transporter occupancy
Nature
1997
663
10
Obesity and addiction: neurobiological overlaps
Obesity Reviews
2013
622
11
Association between decline in brain dopamine activity with age and cognitive and motor impairment in healthy individuals
American Journal of Psychiatry
1998
591
12
Salt and hypertension
American Journal of Clinical Nutrition
1972
567
13
Decreases in Dopamine Receptors but not in Dopamine Transporters in Alcoholics
Alcoholism: Clinical and Experimental Research
1996
530
14
The addicted human brain viewed in the light of imaging studies: brain circuits and treatment strategies
Neuropharmacology
2004
523
15
Addiction Circuitry in the Human Brain
Annual Review of Pharmacology and Toxicology
2012
461
16
Similarity Between Obesity and Drug Addiction as Assessed by Neurofunctional Imaging
Journal of Addictive Diseases
2004
458
17
Role of Dopamine, the Frontal Cortex and Memory Circuits in Drug Addiction: Insight from Imaging Studies
Neurobiology of Learning and Memory
2002
441
18
Sister-chromatid exchanges: A report of the GENE-TOX program
Mutation Research - Reviews in Genetic Toxicology
1981
436
19
Changes in brain glucose metabolism in cocaine dependence and withdrawal
American Journal of Psychiatry
1991
409
20
Addiction: Decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain's control circuit
BioEssays
2010
404
21
?Nonhedonic? food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect
Synapse
2002
400
22
Association of Methylphenidate-Induced Craving With Changes in Right Striato-orbitofrontal Metabolism in Cocaine Abusers: Implications in Addiction
American Journal of Psychiatry
1999
384
23
Effects of chronic cocaine abuse on postsynaptic dopamine receptors
American Journal of Psychiatry
1990
375
24
Imaging endogenous dopamine competition with [11C]raclopride in the human brain
Synapse
1994
362
25
Role of dopamine in drug reinforcement and addiction in humans: results from imaging studies
Behavioural Pharmacology
2002
342
26
Gold nanoparticle imaging and radiotherapy of brain tumors in mice
Nanomedicine
2013
341
27
Food and Drug Reward: Overlapping Circuits in Human Obesity and Addiction
Current Topics in Behavioral Neurosciences
2011
339
28
Exposure to appetitive food stimuli markedly activates the human brain
NeuroImage
2004
330
29
The Addictive Dimensionality of Obesity
Biological Psychiatry
2013
314
30
Regional brain metabolic activation during craving elicited by recall of previous drug experiences
Life Sciences
1999
311
31
Imaging the Effects of Methylphenidate on Brain Dopamine: New Model on Its Therapeutic Actions for Attention-Deficit/Hyperactivity Disorder
Biological Psychiatry
2005
308
32
Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway
Molecular Psychiatry
2011
308
33
Mechanism of action of methylphenidate: Insights from PET imaging studies
Journal of Attention Disorders
2002
296
34
The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence
Brain Research Reviews
2005
296
35
Expectation Enhances the Regional Brain Metabolic and the Reinforcing Effects of Stimulants in Cocaine Abusers
Journal of Neuroscience
2003
293
36
Inverse Association Between BMI and Prefrontal Metabolic Activity in Healthy Adults
Obesity
2009
276
37
Enhanced Striatal Dopamine Release During Food Stimulation in Binge Eating Disorder
Obesity
2011
260
38
Microbeam radiation therapy
Medical Physics
1992
256
39
Abundant alkali-sensitive sites in DNA of human and mouse sperm
Experimental Cell Research
1989
246
40
Neuropathology of ablation of rat gliosarcomas and contiguous brain tissues using a microplanar beam of synchrotron-wiggler-generated X rays
International Journal of Cancer
1998
246
41
Brain DA D2 receptors predict reinforcing effects of stimulants in humans: Replication study
Synapse
2002
242
42
Computed tomography of x-ray index of refraction using the diffraction enhanced imaging method
Physics in Medicine and Biology
2000
241
43
The role of dopamine in motivation for food in humans: implications for obesity
Expert Opinion on Therapeutic Targets
2002
241
44
Subacute neuropathological effects of microplanar beams of x-rays from a synchrotron wiggler.
Proceedings of the National Academy of Sciences of the United States of America
1995
237
45
123I-labeled AM251: a radioiodinated ligand which binds in vivo to mouse brain cannabinoid CB1 receptors
European Journal of Pharmacology
1996
222
46
Common deactivation patterns during working memory and visual attention tasks: An intra-subject fMRI study at 4 Tesla
Human Brain Mapping
2006
218
47
Cigarette smoke inhalation decreases alpha 1-antitrypsin activity in rat lung
Science
1979
215
48
Brain Monoamine Oxidase A Activity Predicts Trait Aggression
Journal of Neuroscience
2008
215
49
Partial Recovery of Brain Metabolism in Methamphetamine Abusers After Protracted Abstinence
American Journal of Psychiatry
2004
210
50
Dopamine increases in striatum do not elicit craving in cocaine abusers unless they are coupled with cocaine cues
NeuroImage
2008
208
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