| # | Title | Journal | Year | Citations |
|---|
| 1 | Features and development of Coot | Acta Crystallographica Section D: Biological Crystallography | 2010 | 22,799 |
| 2 | A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid | Biochemical Journal | 1956 | 13,891 |
| 3 | Overview of theCCP4 suite and current developments | Acta Crystallographica Section D: Biological Crystallography | 2011 | 11,098 |
| 4 | Universal control mechanism regulating onset of M-phase | Nature | 1990 | 2,904 |
| 5 | Glycobiology: Toward Understanding the Function of Sugars | Chemical Reviews | 1996 | 2,750 |
| 6 | Active genes are tri-methylated at K4 of histone H3 | Nature | 2002 | 1,871 |
| 7 | Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides | Nature | 1988 | 1,730 |
| 8 | Identification of the haemoglobin scavenger receptor | Nature | 2001 | 1,488 |
| 9 | Glycosylation and the Immune System | Science | 2001 | 1,487 |
| 10 | Cell-Surface Anchoring of Proteins via Glycosyl-Phosphatidylinositol Structures | Annual Review of Biochemistry | 1988 | 1,305 |
| 11 | Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. | Proceedings of the National Academy of Sciences of the United States of America | 1987 | 1,270 |
| 12 | Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis | Nature | 1989 | 1,261 |
| 13 | Animal Cell Cycles and Their Control | Annual Review of Biochemistry | 1992 | 1,226 |
| 14 | Glycobiology | Annual Review of Biochemistry | 1988 | 1,195 |
| 15 | The Impact of Glycosylation on the Biological Function and Structure of Human Immunoglobulins | Annual Review of Immunology | 2007 | 1,180 |
| 16 | A brave new world of RNA-binding proteins | Nature Reviews Molecular Cell Biology | 2018 | 1,172 |
| 17 | Making sense of it all: bacterial chemotaxis | Nature Reviews Molecular Cell Biology | 2004 | 1,167 |
| 18 | Protein Kinase Inhibitors: Insights into Drug Design from Structure | Science | 2004 | 1,164 |
| 19 | Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG | Nature | 1985 | 1,147 |
| 20 | Presenting your structures: theCCP4mgmolecular-graphics software | Acta Crystallographica Section D: Biological Crystallography | 2011 | 1,133 |
| 21 | Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 1,131 |
| 22 | Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. | EMBO Journal | 1987 | 1,096 |
| 23 | Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin | Nature Immunology | 2005 | 1,055 |
| 24 | The importance of repairing stalled replication forks | Nature | 2000 | 1,008 |
| 25 | Mapping of metabolites in whole animals by 31P NMR using surface coils | Nature | 1980 | 998 |
| 26 | Design principles of biochemical oscillators | Nature Reviews Molecular Cell Biology | 2008 | 970 |
| 27 | The C-type lectin superfamily in the immune system | Immunological Reviews | 1998 | 964 |
| 28 | Crystal Structure of a Neutralizing Human IgG Against HIV-1: A Template for Vaccine Design | Science | 2001 | 870 |
| 29 | Cohesin: Its Roles and Mechanisms | Annual Review of Genetics | 2009 | 869 |
| 30 | Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor | Nature | 1997 | 856 |
| 31 | The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases | EMBO Reports | 2011 | 851 |
| 32 | Integrin Structure, Activation, and Interactions | Cold Spring Harbor Perspectives in Biology | 2011 | 845 |
| 33 | Somatic mutant clones colonize the human esophagus with age | Science | 2018 | 805 |
| 34 | Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: Differentiation antigens of rat lymphocytes | Cell | 1977 | 790 |
| 35 | Crystal Structure of the Potassium Channel KirBac1.1 in the Closed State | Science | 2003 | 763 |
| 36 | Super-resolution microscopy demystified | Nature Cell Biology | 2019 | 754 |
| 37 | Glycosyl-phosphatidylinositol moiety that anchors Trypanosoma brucei variant surface glycoprotein to the membrane | Science | 1988 | 737 |
| 38 | Glycosylation changes of IgG associated with rheumatooid arthritis can activate complement via the mannose-binding protein | Nature Medicine | 1995 | 729 |
| 39 | Molecular interactions on microarrays | Nature Genetics | 1999 | 720 |
| 40 | A transient three-plasmid expression system for the production of high titer retroviral vectors | Nucleic Acids Research | 1995 | 705 |
| 41 | Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis | Lancet, The | 2000 | 700 |
| 42 | Ultraviolet radiation screening compounds | Biological Reviews | 1999 | 677 |
| 43 | Utrophin-Dystrophin-Deficient Mice as a Model for Duchenne Muscular Dystrophy | Cell | 1997 | 667 |
| 44 | Refinement of severely incomplete structures with maximum likelihood inBUSTER–TNT | Acta Crystallographica Section D: Biological Crystallography | 2004 | 666 |
| 45 | The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120 | Journal of Virology | 2002 | 664 |
| 46 | Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene | Nature Neuroscience | 2001 | 661 |
| 47 | Amyloid fibril formation by an SH3 domain | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 654 |
| 48 | Evaluation of Y-chromosomal STRs: a multicenter study | International Journal of Legal Medicine | 1997 | 648 |
| 49 | A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield | Science | 2011 | 644 |
| 50 | Molecular analysis of the association of HLA-B53 and resistance to severe malaria | Nature | 1992 | 638 |
